Isolation of five different primary cell types from a single sample of human skin
Summary: We have developed a technique to isolate primary keratinocytes, melanocytes, fibroblasts, preadipocytes, and microvascular endothelial cells from an individual sample of human skin. The protocol describes step-by-step instructions for processing,
Sylwia Kabacik+5 more
doaj
Doppler effect in vacuum and medium in X-ray range [PDF]
This paper discusses the Doppler effect for radiation emitted by a relativistic oscillator in vacuum described geometrically as an ellipsoid in momentum space. Spectral and angular properties of the Doppler X-ray radiation emitted by a relativistic oscillator moving through a homogeneous medium are considered.
arxiv +1 more source
Bystander effects and their implications for clinical radiation therapy: Insights from multiscale in silico experiments [PDF]
Radiotherapy is a commonly used treatment for cancer and is usually given in varying doses. At low radiation doses relatively few cells die as a direct response to radiation but secondary radiation effects such as DNA mutation or bystander effects affect many cells.
arxiv +1 more source
Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi+6 more
wiley +1 more source
Risk Factors for Childhood Leukemia: Radiation and Beyond
Childhood leukemia (CL) is undoubtedly caused by a multifactorial process with genetic as well as environmental factors playing a role. But in spite of several efforts in a variety of scientific fields, the causes of the disease and the interplay of ...
Janine-Alison Schmidt+7 more
doaj +1 more source
Quantum radiation produced by a uniformly accelerating charged particle in thermal random motion [PDF]
We investigate the properties of quantum radiation produced by a uniformly accelerating charged particle undergoing thermal random motions, which originates from the coupling to the vacuum fluctuations of the electromagnetic field. Because the thermal random motions are regarded to result from the Unruh effect, this quantum radiation is termed Unruh ...
arxiv +1 more source
Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park+6 more
wiley +1 more source
The cognitive consequences of postnatal brain exposure to ionizing radiation (IR) at low to moderate doses in the adult are not fully established. Because of the advent of pediatric computed tomography scans used for head exploration, improving our ...
Céline Serrano+6 more
doaj +1 more source
The effect of Joule heating on the terahertz radiation in the superconductor media [PDF]
Moving vortex lattice in type-II superconductors can result in the radiation of electromagnetic waves in the range of terahertz frequency. The vortex flow dynamics in superconductors follow the London equation. In this paper, the effects of the superconductor coherence length and the London penetration depth on the radiated power is investigated by ...
arxiv +1 more source
Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi+26 more
wiley +1 more source