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Radiation exposure in recurrent medical imaging: identifying drivers and high-risk populations [PDF]

open access: yesFrontiers in Public Health
Medical imaging modalities constitute indispensable diagnostic and therapeutic decision-making tools in contemporary clinical practice. These modalities are pivotal in disease detection, longitudinal monitoring, and treatment response assessment. However,
Juan Chen   +6 more
doaj   +2 more sources

Centella asiatica-Derived Endothelial Paracrine Restores Epithelial Barrier Dysfunction in Radiation-Induced Enteritis

open access: yesCells, 2022
Radiation-induced enteritis is frequently observed following radiotherapy for cancer or occurs due to radiation exposure in a nuclear accident. The loss of the epithelial integrity leads to ‘leaky gut’, so recovery of damaged epithelium is an important ...
Seo Young Kwak   +9 more
doaj   +1 more source

Radiation-Activated PI3K/AKT Pathway Promotes the Induction of Cancer Stem-Like Cells via the Upregulation of SOX2 in Colorectal Cancer

open access: yesCells, 2021
The current treatment strategy for patients with aggressive colorectal cancer has been hampered by resistance to radiotherapy and chemotherapy due to the existence of cancer stem-like cells (CSCs).
Ji-Hye Park   +10 more
doaj   +1 more source

Radiation-Induced Overexpression of TGFβ and PODXL Contributes to Colorectal Cancer Cell Radioresistance through Enhanced Motility

open access: yesCells, 2021
The primary cause of colorectal cancer (CRC) recurrence is increased distant metastasis after radiotherapy, so there is a need for targeted therapeutic approaches to reduce the metastatic-relapse risk.
Hyunjung Lee   +3 more
doaj   +1 more source

Expansion of monocytic myeloid-derived suppressor cells ameliorated intestinal inflammatory response by radiation through SOCS3 expression

open access: yesCell Death and Disease, 2021
Radiation-induced colitis is a common clinical problem after radiation therapy and accidental radiation exposure. Myeloid-derived suppressor cells (MDSCs) have immunosuppressive functions that use a variety of mechanisms to alter both the innate and the ...
You Yeon Choi   +4 more
doaj   +1 more source

ABCA1-Mediated EMT Promotes Papillary Thyroid Cancer Malignancy through the ERK/Fra-1/ZEB1 Pathway

open access: yesCells, 2023
Papillary thyroid cancer (PTC) is the most prevalent histological type of thyroid cancer (TC) worldwide. Although tumor metastasis occurs in regional lymph nodes, distant metastasis (DM) may also occur.
Ji-Hye Park   +11 more
doaj   +1 more source

StemRegenin 1 Mitigates Radiation-Mediated Hematopoietic Injury by Modulating Radioresponse of Hematopoietic Stem/Progenitor Cells

open access: yesBiomedicines, 2023
Hematopoietic injury resulting from the damage of hematopoietic stem/progenitor cells (HSPCs) can be induced by either nuclear accident or radiotherapy.
You Jung Hwang   +9 more
doaj   +1 more source

Radiation exposure of anesthesiologists [PDF]

open access: yesJournal of Clinical Anesthesia, 1991
To determine the level of radiation exposure of anesthesiologists in the operating rooms and cardiac catheterization laboratory.Prospective study of all anesthesia fellows.Operating rooms (ORs) and radiology department of a tertiary care pediatric hospital.Anesthesiologists caring for patients in a pediatric hospital requiring anesthesia or monitored ...
K H, Henderson   +4 more
openaire   +2 more sources

Metallothionein 2 activation by pravastatin reinforces epithelial integrity and ameliorates radiation-induced enteropathy

open access: yesEBioMedicine, 2021
: Background: Radiotherapy or accidental exposure to ionizing radiation causes severe damage of healthy intestinal tissues. Intestinal barrier function is highly sensitive to ionizing radiation, and loss of epithelial integrity results in mucosal ...
Seo Young Kwak   +8 more
doaj   +1 more source

Deep models of integrated multiscale molecular data decipher the endothelial cell response to ionizing radiation

open access: yesiScience, 2022
Summary: The vascular endothelium is a hot spot in the response to radiation therapy for both tumors and normal tissues. To improve patient outcomes, interpretable systemic hypotheses are needed to help radiobiologists and radiation oncologists propose ...
Ian Morilla   +16 more
doaj   +1 more source

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