Results 71 to 80 of about 65,131 (260)

Extracellular Vesicles for the Treatment of Radiation Injuries. [PDF]

Front Pharmacol, 2021
Nanduri LSY, Duddempudi PK, Yang WL, Tamarat R, Guha C.   +4 more
europepmc   +1 more source

Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing

Advanced Science, EarlyView.
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale, Marie Celine Lefevre, Alessio Carmignani, Maria Cristina Ceccarelli, Matteo Battaglini, Attilio Marino, Gianni Ciofani   +6 more
wiley   +1 more source

In Situ Genetic Engineering Facilitates MMP‐9‐Responsive TIMP1 Release Through Proteolytic Cleavage to Boost Diabetic Wound Healing

Advanced Science, EarlyView.
This study develops an MMP‐9‐responsive protein release system that transforms resident cells into drug depots through in situ genetic engineering. Anchored to the membrane, the therapeutic protein TIMP1 is selectively released upon MMP‐9 cleavage.
Yuan Zhang, Jiani Deng, Man Yee Cheung, Tingting Fu, Xufeng Qi, Dongqing Cai, Jianmin Sun, Gang Lu, Peng Shi, Wai‐Yee Chan, Xu Li, Hui Zhao   +11 more
wiley   +1 more source

Which place for stem cell therapy in the treatment of acute radiation syndrome?

Folia Histochemica et Cytobiologica, 2005
Radiation-induced (RI) tissue injuries can be caused by radiation therapy, nuclear accidents or radiological terrorism. Notwithstanding the complexity of RI pathophysiology, there are some effective approaches to treatment of both acute and chronic ...
Jean-François Mayol, Francis HĂŠrodin, FrĂŠdĂŠric Mourcin, Michel Drouet   +3 more
doaj   +1 more source

Radiation Injuries [PDF]

The International Journal of Lower Extremity Wounds, 2011
Chunmeng, Shi, Shuliang, Lu
openaire   +2 more sources

Ultrasound‐Activatable Piezoelectric Hydrogel Reprograms Mitochondrial Epigenetics for Osteoarthritis Therapy via the mTOR/GATD3A Axis

Advanced Science, EarlyView.
An ultrasound‐activatable piezoelectric hydrogel reprograms chondrocyte mitochondrial epigenetics via the mTOR/GATD3A axis, clearing damaged mitochondria and alleviating osteoarthritis progression in both mouse models and human cartilage explants. ABSTRACT The avascular nature of cartilage hinders drug delivery for osteoarthritis (OA) therapy.
Hui Zheng, Pengfei Yan, Peng Liu, Chang Yan, Mengqi Zhao, Zuyong Wang, Chao Ma, Rongkai Zhang, Xi Cui, Swee Hin Teoh   +9 more
wiley   +1 more source

Radiation-induced intestinal injury

Терапевтический архив
This article addresses theoretical and clinical aspects of radiation-induced intestinal injuries, which complicate radiation therapy for malignant neoplasms of the abdominal and pelvic organs. Many clinical aspects of this issue remain unknown due to the
Asfold I. Parfenov, Lilia K. Indejkina, Elena A. Sabelnikova, Aleksandr V. Leontiev, Alina A. Makarova   +4 more
doaj   +1 more source

Effects of captopril against radiation injuries in the Göttingen minipig model of hematopoietic-acute radiation syndrome. [PDF]

PLoS One, 2021
Rittase WB, McCart EA, Muir JM, Bouten RM, Slaven JE, Mungunsukh O, Bylicky MA, Wilkins WL, Lee SH, Gudmundsson KO, Di Pucchio T, Olsen CH, Du Y, Day RM.   +13 more
europepmc   +1 more source

Ultra‐Radiostable Covalent Conformationally Interlocked Networks Enabling a Universal Radiometal‐Labeling Platform for Cancer Radioembolization

Advanced Science, EarlyView.
Conjugated poly(imide dioxime)‐based microspheres establish a radiometal coordination‐driven conformational interlocked network with ultra‐high radiostability. This platform enables low‐temperature, multi‐radionuclide labeling for SPECT/PET/MRI imaging and radionuclide therapy. Mechanistic insights from EXAFS and DFT reveal enhanced stability, while in
Xiao Xu, Zhenwen Zhao, Yangjie Wang, Zhigang Liu, Zhijie Liu, Xiaoling Li, Zhichen Mao, Lu Xu, Gan Lin, Gang Liu, Hongjuan Ma   +10 more
wiley   +1 more source

From Mechanism to Therapy: The Role of MSC-EVs in Alleviating Radiation-Induced Injuries

Pharmaceutics
Radiation injury is a severe issue in both nuclear accidents and cancer radiotherapy. Ionizing radiation impairs the regenerative and repair capabilities of tissues and organs, resulting in a scarcity of effective therapeutic approaches to prevent or ...
Chong Huang, Heng Li, Zhiyue Zhang, Ting Mou, Dandan Wang, Chenlu Li, Lei Tian, Chunlin Zong   +7 more
doaj   +1 more source