Results 61 to 70 of about 513,484 (358)

Residency Match Trends, Racial Disparity, and Matching Amid a Pandemic

Advances in Radiation Oncology, 2021
Purpose: Radiation oncology has been facing an evolving crisis in recruitment for several years, and the events of 2020 to 2021 will certainly add to that crisis with the urgency of addressing systemic racial injustice amid a global pandemic. The purpose
April Vassantachart, MD, Lindsay Hwang, MD, Andrew Vassantachart, BS, Richard Jennelle, MD   +3 more
doaj  

Treatment-Related Decisional Conflict, Quality of Life, and Comorbid Illness in Older Adults with Cancer [PDF]

, 2017
As the aging population in the nation increases, cancer diagnoses in this age group will also increase. The many chronic medical conditions associated with older adults are confounded by a diagnosis of cancer.
Kates, PhD, MSN, GNP-BC, Jeannette
core   +1 more source

SYSTEMS-2: a randomised phase II study of radiotherapy dose escalation for pain control in malignant pleural mesothelioma [PDF]

, 2018
SYSTEMS-2 is a randomised study of radiotherapy dose escalation for pain control in 112 patients with malignant pleural mesothelioma (MPM). Standard palliative (20Gy/5#) or dose escalated treatment (36Gy/6#) will be delivered using advanced radiotherapy ...
Alexander, L., Ashton, M., Chalmers, A.J., Currie, S., Franks, K., Kelly, C., Laird, B., Macleod, N., Moore, K., O'Rourke, N., Stobo, J., Valentine, R.   +11 more
core   +2 more sources

TRPM8 levels determine tumor vulnerability to channel agonists

Molecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo, Francesco Giuseppe Carbone, Kristi Buzo, Nicole Annesi, Sacha Genovesi, Annalisa Lorenzato, Karen Widmann, Michela Libergoli, Elisa Marmocchi, Giovanni Bertalot, Alberto Brolese, Mauro Giulio Papotti, Luca Molinaro, Orazio Caffo, Mattia Barbareschi, Alberto Bardelli, Alessandro Romanel, Sabrina Arena, Andrea Lunardi   +18 more
wiley   +1 more source

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

Molecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed, Lucas Mani, Muhammad Bilal Mirza, Ashtyn McAdoo, Takahito Kondo, Hidenori Tanaka, Nicole Meeks, Eben Rosenthal, Marisa Hom   +8 more
wiley   +1 more source

Radiotherapy for pelvic nodal recurrences after radical prostatectomy: patient selection in clinical practice

Radiation Oncology, 2019
Aim There is no general consensus on the optimal treatment for prostate cancer (PC) patients with intrapelvic nodal oligorecurrences after radical prostatectomy.
Cedric Panje, Thomas Zilli, Alan Dal Pra, Winfried Arnold, Kathrin Brouwer, Helena I. Garcia Schüler, Silvia Gomez, Fernanda Herrera, Kaouthar Khanfir, Alexandros Papachristofilou, Gianfranco Pesce, Christiane Reuter, Hansjörg Vees, Daniel Zwahlen, Paul Martin Putora   +14 more
doaj   +1 more source

Focal Spot, Fall/Winter 1991 [PDF]

, 1991
https://digitalcommons.wustl.edu/focal_spot_archives/1059/thumbnail ...

core   +1 more source

Recent advances in radiation oncology [PDF]

ecancermedicalscience, 2017
Radiotherapy (RT) is very much a technology-driven treatment modality in the management of cancer. RT techniques have changed significantly over the past few decades, thanks to improvements in engineering and computing. We aim to highlight the recent developments in radiation oncology, focusing on the technological and biological advances.
Anna Starzyńska, Delia Ciardo, Alessia Surgo, Damaris Patricia Rojas, Damaris Patricia Rojas, Giulia Marvaso, Rosalinda Ricotti, Cristina Garibaldi, Barbara Alicja Jereczek-Fossa, Maria Cristina Leonardi, Federica Cattani, Samantha Dicuonzo, Samantha Dicuonzo   +12 more
openaire   +3 more sources

The subcellular distribution of phosphorylated Y‐box‐binding protein‐1 at S102 in colorectal cancer patients, stratified by KRAS mutational status and clinicopathological features

Molecular Oncology, EarlyView.
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau, Stephan Forchhammer, Birgit Fehrenbacher, Lejla Mahmutovic, Marcus Scharpf, Gunnar Blumenstock, Martin Schaller, Irina Bonzheim, Shayan Khozooei, Mahmoud Toulany   +9 more
wiley   +1 more source

Pathways for Recruiting and Retaining Women and Underrepresented Minority Clinicians and Physician Scientists Into the Radiation Oncology Workforce: A Summary of the 2019 ASTRO/NCI Diversity Symposium Session at the ASTRO Annual Meeting

Advances in Radiation Oncology, 2020
Diversifying the radiation oncology workforce is an urgent and unmet need. During the American Society of Radiation Oncology (ASTRO) 2019 Annual Meeting, ASTRO's Committee on Health Equity, Diversity, and Inclusion (CHEDI) and the National Cancer ...
Gita Suneja, MD, MSHP, Malcolm D. Mattes, MD, Raymond B. Mailhot Vega, MD, MPH, Freddy E. Escorcia, MD, PhD, Colleen Lawton, MD, Joel Greenberger, MD, Aparna H. Kesarwala, MD, PhD, Alexander Spektor, MD, PhD, Bhadrasain Vikram, MD, Curtiland Deville, MD, Malika Siker, MD   +10 more
doaj