Results 41 to 50 of about 3,589,018 (297)

Knowledge and attitude of dentists regarding radiation safety in government dental clinics in Khartoum, Sudan [PDF]

, 2015
Magister Scientiae Dentium - MSc(Dent)The level of knowledge and the attitude of dentists regarding radiation safety will have a direct impact on patient exposure to radiation.
Elmukhtar, Yasir Mohamed
core   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

The Evaluation of Frequencies of Cytogenetic Biomarkers in Lymphocyte of Residents from High Natural Radiation Area in West Sulawesi, Indonesia [PDF]

, 2022
Residents living in high natural radiation areas may pose health consequences such as cancer. The study aims to evaluate the frequencies of cytogenetic biomarkers covering micronuclei (MN), nucleoplasmic bridge (NPB), and nuclear bud (NBUD) with the ...
Purnami, Sofiati; Center for Technology of Radiation Safety and Metrology, National Nuclear Energy Agency of Indonesia, South Jakarta, 12440, Indonesia, Surniyantoro, Harry Nugroho Eko; Center for Technology of Radiation Safety and Metrology, National Nuclear Energy Agency of Indonesia, South Jakarta, 12440, Indonesia, Nurhayati, Siti; Center for Technology of Radiation Safety and Metrology, National Nuclear Energy Agency of Indonesia, South Jakarta, 12440, Indonesia, Ramadhani, Dwi; Center for Technology of Radiation Safety and Metrology, National Nuclear Energy Agency of Indonesia, South Jakarta, 12440, Indonesia, Rahajeng, Nastiti; Center for Technology of Radiation Safety and Metrology, National Nuclear Energy Agency of Indonesia, South Jakarta, 12440, Indonesia, Syaifudin, Mukh; Center for Technology of Radiation Safety and Metrology, National Nuclear Energy Agency of Indonesia, South Jakarta, 12440, Indonesia   +5 more
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Obtaining stable strains of microorganisms with increased production of hydrolytic enzymes by methods of induced mutagenesis and their characteristics [PDF]

BIO Web of Conferences
In order to increase the level of production of hydrolytic enzymes of natural producers and select highly productive microorganisms, a study was carried out on the effectiveness of various approaches to induced mutagenesis, as well as a comparative study
Valiullin L. R., Mukhammadiev Rin S., Mukhammadiev Rish S., Saifullin A. S., Samsonov A. I., Gumerov V. G., Yarullin A. I., Baryshev M. G.   +7 more
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Status and Assessment Method of Nuclear Safety Analysis Software in China

Frontiers in Energy Research, 2021
In recent years, China’s nuclear power industry has enjoyed a good momentum of development, and related companies have also developed many nuclear analysis software applications.
Xinli Gao, Xinli Gao, Jianping Jing, Jianping Jing, Xiangzhen Han, Xiangzhen Han, Bin Jia, Bin Jia, Xinlu Tian, Xinlu Tian, Fudong Liu, Fudong Liu, Chunming Zhang   +12 more
doaj   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

Further Characterization of the Mitigation of Radiation Lethality by Protective Wounding

, 2017
There continues to be a major effort in the United States to develop mitigators for the treatment of mass casualties that received high-intensity acute ionizing radiation exposures from the detonation of an improvised nuclear device during a radiological
Joy Garrett, Katharina Lane, Marc S. Mendonca, Lane, Katharina, Garrett, Joy, Rebecca Joel, Joel, Rebecca, Orschell, Christie M., Christie M. Orschell, Mendonca, Marc S., Joseph R. Dynlacht, Dynlacht, Joseph R.   +11 more
core   +1 more source

Use of HRM-Analysis of the Melting Curves Obtained after Amplification of VNTR-Loci for Identification and Differentiation of Brucella Strains

Проблемы особо опасных инфекций
The aim of the present study was to evaluate the effectiveness of analysis of the high resolution melting curves obtained after amplification of VNTR loci for the identification and differentiation of Brucella strains.Materials and methods. 16 strains of
E. A. Anisimova, D. A. Mirgazov, E. A. Dodonova, I. A. Elizarova, E. V. Pankova, K. A. Osyanin   +5 more
doaj   +1 more source