Results 31 to 40 of about 152,593 (307)
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Scientific Reports, 2017 Passive radiation shielding is a mandatory element in the design of an integrated solution to mitigate the effects of radiation during long deep space voyages for human exploration.
Livio Narici +6 more
doaj +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Nuclear Engineering and Technology, 2022 Advanced radiation applications have been widely used and extended to many fields. As a result of this fact, choosing an appropriate shielding material based on the radiation application has become vital.
Ferdi. Akman +6 more
doaj +1 more source
Aging and Cancer, EarlyView.ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef +2 more
wiley +1 more source
IEC Fusor Mobile Shielding Unit [PDF]
, 2017 The VCU Inertial Electrostatic Confinement (IEC) Fusor Senior Design Project provides Virginia Commonwealth University (VCU) with a mobile fusor complete with the necessary shielding to protect operators as well as the general public from potentially ...
Balducci, Dominic +4 more
core +1 more source
, 2016 We develop a general model of coherent synchrotron radiation (CSR) impedance with shielding provided by two parallel conducting plates. This model allows us to easily reproduce all previously known analytical CSR wakes and to expand the analysis to the ...
Stupakov, Gennady, Zhou, Demin
core +2 more sources
Photodissociation and photoionisation of atoms and molecules of astrophysical interest [PDF]
, 2017 A new collection of photodissociation and photoionisation cross sections for 102 atoms and molecules of astrochemical interest has been assembled, along with a brief review of the basic processes involved.
Bosman, A. D. +2 more
core +3 more sources
Advanced Engineering Materials, EarlyView.The growing demand for lightweight, nontoxic, and multifunctional gamma shielding materials has intensified efforts to find alternatives to conventional lead and aluminum‐based protectants. In this work, we develop epoxy quartz fabric composites reinforced with cobalt chloride (CoCl2) microparticles, fabricated via hand lay‐up with varying filler ...
Summan Urooge +7 more
wiley +1 more source
Influence of an Argon/Silane Atmosphere on the Temperature of a Thermal Plasma
Advanced Engineering Materials, EarlyView.The influence of a silane‐doped argon atmosphere on the chemical composition and temperature of a thermal nontransferring argon plasma is investigated using optical emission spectroscopy. As a result of the high amount of free electrons resulting from the stepwise ionization and dissociation of the silane molecule, even a silane addition of 0.01 vol ...
Lena Kreie +4 more
wiley +1 more source