Results 111 to 120 of about 1,165,688 (303)

Targeting the CRYAB/β‐Catenin Axis with an MMP‐9‐Responsive Hydrogel Disrupts CTC Clusters to Suppress Progression of Hepatocellular Carcinoma after Radiofrequency Ablation

open access: yesAdvanced Science, EarlyView.
The graphical abstract illustrates that sublethal thermal stress after iRFA upregulates the chaperone CRYAB in residual HCC cells, which stabilizes β‐catenin and drives a dual pathological program, including EMT and N2‐TAN polarization, thereby leading to heterotypic CTC cluster formation. The MMP‐9‐responsive hydrogel (XB@Gel) delivers XAV‐939 and BMS‐
Hui Chen   +8 more
wiley   +1 more source

Magnetically Guided Macrophage Immunobots Coordinate Iron‐Metabolic Cascades and Immunogenic Ferroptosis for Tumor Immunotherapy

open access: yesAdvanced Science, EarlyView.
Magnetically guided macrophage immunobots integrate active tumor targeting with immunometabolic therapy. After systemic administration, magnetic actuation enhances immunobot retention and tumor penetration, while LPS‐functionalized FePt microrollers sustain M1‐like polarization through inflammatory and iron‐amplified oxidative signaling and trigger ...
Xirui Zeng   +7 more
wiley   +1 more source

A Review of Sterilization Methods and Their Commercial Impacts on Polysaccharide-Based Biomaterials

open access: yesMacromol
The most significant barrier against biopolymers’ commercialization is their sensitivity to external factors and poor material properties. In recent years, significant progress has been made to enhance these materials so that they are able to provide ...
Evan Moore   +2 more
doaj   +1 more source

Characterizing Biopolymer Electrolytes in Zinc–Air Batteries: Challenges, Best Practices, and a Robust Workflow Guiding Future Research Paths

open access: yesAdvanced Energy Materials, EarlyView.
Bio‐based gel polymer electrolytes promise sustainable, mechanically adaptable zinc–air batteries, yet their progress is constrained by inconsistent characterization. This review critically links formulation, structure, interfaces, and cell performance, identifies methodological gaps under alkaline operating conditions, and proposes application ...
Matteo Milanesi   +6 more
wiley   +1 more source

Packaging used in radiation sterilization [PDF]

open access: yes, 2016
Przeznaczone do sterylizacji radiacyjnej opakowania muszą spełniać specjalne wymagania. Materiał z jakiego są wykonane, ich formy i kształty uzależnione są ściśle od jednostkowych potrzeb obiektu poddawanego procesowi sterylizacji.
Kornacka, E. M.
core  

Fluorescent Hydrogel‐Based Strain Sensor With Machine Learning‐Augmented Performance

open access: yesAdvanced Intelligent Discovery, EarlyView.
Fluorescent hydrogel strain sensor based on carbon quantum dots enabling optical readout of deformation through strain‐dependent emission changes, coupled with Random Forest analysis to capture nonlinear fluorescence‐concentration relationships and identify optimal sensing conditions. Hydrogels are ideal matrices for bio‐integrated wearable sensors due
Tailai Chen   +4 more
wiley   +1 more source

Zebrafish xenograft models as a fast platform for metastasis diagnosis and cisplatin response of head and neck squamous cell carcinoma

open access: yesAnimal Models and Experimental Medicine, EarlyView.
A zebrafish xenograft model accurately distinguishes metastatic from non‐metastatic HNSCC and recapitulates cisplatin sensitivity/resistance patterns. Using patient‐derived tumors, it predicts individual therapeutic responses, offering a rapid, clinically applicable platform for guiding personalized treatment. Abstract Background Head and neck squamous
Lu Chen   +11 more
wiley   +1 more source

Current Status of Non-Thermal Sterilization by Pet Food Raw Ingredients

open access: yesFood Science of Animal Resources
Recently, as the concept of pet food that satisfies both nutritional needs and the five senses has evolved, so too has the demand for effective pet food non-thermal sterilization methods.
Ui-Bin Baek, Hack-Youn Kim
doaj   +1 more source

Application evaluation of a polydimethylsiloxane low-viscosity for cryopreservation and radiation sterilization of human cadaveric vascular allografts. [PDF]

open access: yesСаратовский научно-медицинский журнал, 2016
Aim: to investigate potential cryo- and radioprotective properties of a polydimethylsiloxane of low viscosity to provide safe and reliable cryopreservation and radiation sterilization of human cadaveric vascular allografts. Material and methods.
Lauk-Dubitsky S.E.   +15 more
doaj  

Avaliação dos efeitos da esterilização por radiação gama na eficiência da ação antimicrobiana de poliamida 6 e PEAD aditivados com agentes antimicrobianos [PDF]

open access: yes, 2014
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-Graduação em Engenharia Química, Florianópolis, 2014.Desde as descobertas de Pasteur, a humanidade vem buscando formas de controlar os micro-organismos ...
Fernandes, Ramon Salvan
core  

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