Results 1 to 10 of about 6,862,572 (354)

Radiation therapy‐associated toxicity: Etiology, management, and prevention

Ca, 2021
Radiation therapy (RT) is a curative treatment for many malignancies and provides effective palliation in patients with tumor‐related symptoms. However, the biophysical effects of RT are not specific to tumor cells and may produce toxicity due to ...
Kyle Wang, J. Tepper
semanticscholar   +1 more source

Nanoscale coordination polymers induce immunogenic cell death by amplifying radiation therapy mediated oxidative stress

Nature Communications, 2021
Radiation therapy can potentially induce immunogenic cell death, thereby priming anti-tumor adaptive immune responses. However, radiation-induced systemic immune responses are very rare and insufficient to meet clinical needs.
Zhusheng Huang, Yuxiang Wang, Dan Yao, Jinhui Wu, Yiqiao Hu, A. Yuan   +5 more
semanticscholar   +1 more source

The abscopal effect of radiation therapy.

Future Oncology, 2021
Radiation therapy (RT) in some cases results in a systemic anticancer response known as the abscopal effect. Multiple hypotheses support the role of immune activation initiated by RT-induced DNA damage.
D. J. Craig, Nisha S Nanavaty, Monika Devanaboyina, L. Stanbery, Danae Hamouda, G. Edelman, L. Dworkin, J. Nemunaitis   +7 more
semanticscholar   +1 more source

Feasibility of linac-based fractionated stereotactic radiotherapy and stereotactic radiosurgery for patients with up to ten brain metastases

Radiation Oncology, 2022
Background Linac-based fractionated stereotactic radiotherapy (fSRT) and stereotactic radiosurgery (SRS) are increasingly being used to manage patients with multiple metastases.
Masanori Hirata, Kazuaki Yasui, Naofumi Oota, Hirofumi Ogawa, Tsuyoshi Onoe, Sayo Maki, Yusuke Ito, Kenji Hayashi, Hirofumi Asakura, Shigeyuki Murayama, Koichi Mitsuya, Shoichi Deguchi, Katsumasa Nakamura, Nakamasa Hayashi, Tetsuo Nishimura, Hideyuki Harada   +15 more
doaj   +1 more source

Radiation therapy in head and neck cancer

Saudi Medical Journal, 2021
This review summarizes the beginning of radiotherapy, techniques of modern radiation therapy with different types, toxicities induced by radiotherapy and their management.
A. Alfouzan
semanticscholar   +1 more source

Deep learning method for prediction of patient-specific dose distribution in breast cancer

Radiation Oncology, 2021
Background Patient-specific dose prediction improves the efficiency and quality of radiation treatment planning and reduces the time required to find the optimal plan. In this study, a patient-specific dose prediction model was developed for a left-sided
Sang Hee Ahn, EunSook Kim, Chankyu Kim, Wonjoong Cheon, Myeongsoo Kim, Se Byeong Lee, Young Kyung Lim, Haksoo Kim, Dongho Shin, Dae Yong Kim, Jong Hwi Jeong   +10 more
doaj   +1 more source

Long-term survival after definitive proton beam therapy for oligorecurrent esophageal squamous cell carcinoma: a case report

Journal of Medical Case Reports, 2022
Background Radical esophagectomy for esophageal squamous cell carcinoma has improved survival, but the rate of recurrence is high. Patients of recurrent esophageal squamous cell carcinoma after failure of chemotherapy have a poor prognosis.
Yojiro Ishikawa, Motohisa Suzuki, Hisashi Yamaguchi, Ichiro Seto, Masanori Machida, Yoshiaki Takagawa, Keiichi Jingu, Yasuyuki Kikuchi, Masao Murakami   +8 more
doaj   +1 more source

Successful treatment with proton beam therapy for a solitary sternal metastasis of breast cancer: a case report

Journal of Medical Case Reports, 2022
Background Breast cancer infrequently metastasizes to the sternum as solitary metastasis. We experienced successful treatment with proton beam therapy for a case of sternal metastasis of breast cancer.
Yojiro Ishikawa, Motohisa Suzuki, Hisashi Yamaguchi, Ichiro Seto, Masanori Machida, Yoshiaki Takagawa, Keiichi Jingu, Yasuyuki Kikuchi, Masao Murakami   +8 more
doaj   +1 more source

Microenvironment and Radiation Therapy [PDF]

BioMed Research International, 2013
Dependency on tumor oxygenation is one of the major features of radiation therapy and this has led many radiation biologists and oncologists to focus on tumor hypoxia. The first approach to overcome tumor hypoxia was to improve tumor oxygenation by increasing oxygen delivery and a subsequent approach was the use of radiosensitizers in combination with ...
Yoshimura, Michio, Itasaka, Satoshi, Harada, Hiroshi, Hiraoka, Masahiro   +3 more
openaire   +3 more sources

Pomiferin Exerts Antineuroinflammatory Effects through Activating Akt/Nrf2 Pathway and Inhibiting NF-κB Pathway

Mediators of Inflammation, 2022
Background. Neurodegenerative diseases, including Alzheimer’s disease, Parkinson’s disease, and Huntington’s disease, are mainly characterized by progressive motor, sensory, or cognitive dysfunction in patients.
Yan Zhao, Yuxuan Sang, Yanan Sun, Jie Wu
doaj   +1 more source