Results 1 to 10 of about 6,788,828 (423)

Deep learning method for prediction of patient-specific dose distribution in breast cancer

Radiation Oncology, 2021
Background Patient-specific dose prediction improves the efficiency and quality of radiation treatment planning and reduces the time required to find the optimal plan. In this study, a patient-specific dose prediction model was developed for a left-sided
Sang Hee Ahn, EunSook Kim, Chankyu Kim, Wonjoong Cheon, Myeongsoo Kim, Se Byeong Lee, Young Kyung Lim, Haksoo Kim, Dongho Shin, Dae Yong Kim, Jong Hwi Jeong   +10 more
doaj   +1 more source

Bio-Inspired Strategies for Optimizing Radiation Therapy under Uncertainties [PDF]

2023, 2023
Radiation therapy is a critical component of cancer treatment. However, the delivery of radiation poses inherent challenges, particularly in minimizing radiation exposure to healthy organs surrounding the tumor site. One significant contributing factor to this challenge is the patient's respiration, which introduces uncertainties in the precise ...
arxiv   +1 more source

Feasibility of linac-based fractionated stereotactic radiotherapy and stereotactic radiosurgery for patients with up to ten brain metastases

Radiation Oncology, 2022
Background Linac-based fractionated stereotactic radiotherapy (fSRT) and stereotactic radiosurgery (SRS) are increasingly being used to manage patients with multiple metastases.
Masanori Hirata, Kazuaki Yasui, Naofumi Oota, Hirofumi Ogawa, Tsuyoshi Onoe, Sayo Maki, Yusuke Ito, Kenji Hayashi, Hirofumi Asakura, Shigeyuki Murayama, Koichi Mitsuya, Shoichi Deguchi, Katsumasa Nakamura, Nakamasa Hayashi, Tetsuo Nishimura, Hideyuki Harada   +15 more
doaj   +1 more source

Long-term survival after definitive proton beam therapy for oligorecurrent esophageal squamous cell carcinoma: a case report

Journal of Medical Case Reports, 2022
Background Radical esophagectomy for esophageal squamous cell carcinoma has improved survival, but the rate of recurrence is high. Patients of recurrent esophageal squamous cell carcinoma after failure of chemotherapy have a poor prognosis.
Yojiro Ishikawa, Motohisa Suzuki, Hisashi Yamaguchi, Ichiro Seto, Masanori Machida, Yoshiaki Takagawa, Keiichi Jingu, Yasuyuki Kikuchi, Masao Murakami   +8 more
doaj   +1 more source

Successful treatment with proton beam therapy for a solitary sternal metastasis of breast cancer: a case report

Journal of Medical Case Reports, 2022
Background Breast cancer infrequently metastasizes to the sternum as solitary metastasis. We experienced successful treatment with proton beam therapy for a case of sternal metastasis of breast cancer.
Yojiro Ishikawa, Motohisa Suzuki, Hisashi Yamaguchi, Ichiro Seto, Masanori Machida, Yoshiaki Takagawa, Keiichi Jingu, Yasuyuki Kikuchi, Masao Murakami   +8 more
doaj   +1 more source

Microenvironment and Radiation Therapy [PDF]

BioMed Research International, 2013
Dependency on tumor oxygenation is one of the major features of radiation therapy and this has led many radiation biologists and oncologists to focus on tumor hypoxia. The first approach to overcome tumor hypoxia was to improve tumor oxygenation by increasing oxygen delivery and a subsequent approach was the use of radiosensitizers in combination with ...
Yoshimura, Michio, Itasaka, Satoshi, Harada, Hiroshi, Hiraoka, Masahiro   +3 more
openaire   +3 more sources

The Use of Biomaterials in Internal Radiation Therapy [PDF]

, 2020
Radiotherapy has become one of the most prominent and effective modalities for cancer treatment and care. Ionising radiation, delivered either from external or internal sources, can be targeted to cancerous cells causing damage to DNA that can induce ...
Ahmed, Ifty, Arafat, Abul, Layfield, Rob, Milborne, Ben, Thompson, Alexander   +4 more
core   +2 more sources

Pomiferin Exerts Antineuroinflammatory Effects through Activating Akt/Nrf2 Pathway and Inhibiting NF-κB Pathway

Mediators of Inflammation, 2022
Background. Neurodegenerative diseases, including Alzheimer’s disease, Parkinson’s disease, and Huntington’s disease, are mainly characterized by progressive motor, sensory, or cognitive dysfunction in patients.
Yan Zhao, Yuxuan Sang, Yanan Sun, Jie Wu
doaj   +1 more source

The use of hyperbaric oxygen to treat actinic rectal fistula after SpaceOAR use and radiotherapy for prostate cancer: a case report

BMC Urology, 2020
Background In definitive radiation therapy for prostate cancer, the SpaceOAR® System, a hydrogel spacer, is widely used to decrease the irradiated dose and toxicity of rectum.
Tairo Kashihara, Koji Inaba, Motokiyo Komiyama, Hiroki Nakayama, Kotaro Iijima, Shie Nishioka, Hiroyuki Okamoto, Nao Kikkawa, Yuko Kubo, Satoshi Shima, Satoshi Nakamura, Ayaka Takahashi, Kana Takahashi, Kae Okuma, Naoya Murakami, Hiroshi Igaki, Yuko Nakayama, Arinobu Fukunaga, Yoshiyuki Matsui, Hiroyuki Fujimoto, Jun Itami   +20 more
doaj   +1 more source

Factors associated with overall survival, progression-free survival and toxicity in patients with small cell lung cancer and thoracic irradiation in a clinical real-world setting

Radiation Oncology, 2023
Background Small-cell lung cancer (SCLC) is a malignant tumor known for its poor prognosis. In addition to chemotherapy and immunotherapy irradiation plays a big role especially in inoperability.
Marie-Theres Kassik, Dirk Vordermark, Christine Kornhuber, Daniel Medenwald   +3 more
doaj   +1 more source