Results 71 to 80 of about 6,899,989 (399)

Chemoradiation for elderly patients (≥ 65 years) with esophageal cancer: a retrospective single-center analysis

open access: yesRadiation Oncology, 2022
Background Present studies on the efficacy and safety of curative chemoradiation therapy (CRT) with esophageal cancer reflect heterogenous results especially in elderly patients.
Philipp Linde   +8 more
doaj   +1 more source

Emerging role of MRI in radiation therapy

open access: yesJournal of Magnetic Resonance Imaging, 2018
Advances in multimodality imaging, providing accurate information of the irradiated target volume and the adjacent critical structures or organs at risk (OAR), has made significant improvements in delivery of the external beam radiation dose.
H. Chandarana   +3 more
semanticscholar   +1 more source

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

open access: yesMolecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen   +12 more
wiley   +1 more source

Selection Strategy of Jaw Tracking in VMAT Planning for Lung SBRT

open access: yesFrontiers in Oncology, 2022
PurposeThis study aimed to investigate the dosimetric effect and delivery reliability of jaw tracking (JT) with increasing planning target volume (PTV) for lung stereotactic body radiation therapy (SBRT) plans.
Wuji Sun   +12 more
doaj   +1 more source

Intensity-modulated radiation therapy: a review with a physics perspective

open access: yesRadiation Oncology Journal, 2018
Intensity-modulated radiation therapy (IMRT) has been considered the most successful development in radiation oncology since the introduction of computed tomography into treatment planning that enabled three-dimensional conformal radiotherapy in 1980s ...
B. Cho
semanticscholar   +1 more source

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

open access: yesMolecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova   +18 more
wiley   +1 more source

Oxygen Deprivation Modulates EGFR and PD-L1 in Squamous Cell Carcinomas of the Head and Neck

open access: yesFrontiers in Oncology, 2021
Abundance and signaling of the epidermal growth factor receptor (EGFR) and programmed cell death protein ligand 1 (PD-L1) in head and neck squamous cell carcinoma (HNSCC) are not only genetically determined but are also subject to the traits of the tumor
Sebastian Zahnreich   +6 more
doaj   +1 more source

Neuroticism and responses to social comparison among cancer patients [PDF]

open access: yes, 2009
The present study examined how the effects of three audiotapes containig different types of social comparison information on the mood of cancer patients depended on the level of neuroticism.
Bennenbroek, F.T.C.   +6 more
core   +3 more sources

Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren   +16 more
wiley   +1 more source

Intravenous contrast media in radiation therapy planning computed tomography scans – Current practice in Ireland

open access: yesTechnical Innovations & Patient Support in Radiation Oncology, 2019
Introduction: While Computerised Tomography (CT) remains the gold standard in radiation therapy (RT) planning, inferior soft tissue definition remains a challenge.
Shane Minogue   +3 more
doaj  

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