Results 71 to 80 of about 972,051 (351)
Molecular Oncology, EarlyView.Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed +8 more
wiley +1 more source
Frontiers in Oncology, 2020 Background: Radiobiological model-based studies of photon-modulated radiotherapy for pancreatic cancer have reported reduced gastrointestinal (GI) toxicity, although the risk is still high. The purpose of this study was to investigate the potential of 3D-
Vijay P. Raturi +17 more
doaj +1 more source
Antioxidants and Radiation Therapy [PDF]
The Journal of Nutrition, 2004 The American Cancer Society estimates 1,368,050 new cancer cases in 2004 and 536,700 deaths from the disease. Although cancer rates for different sites vary widely, the 5-year relative survival rate for all cancers combined is estimated at 63%. Among the many possible causes of cancer, reactive oxygen species (ROS) have been implicated in the onset and
openaire +3 more sources
Computationally Modeling Compton Scattering to Understand Radiation Therapy [PDF]
, 2012 Radiation therapy is becoming a popular method of cancer treatment due to its effectiveness and precision. Improvements in radiation therapy treatments rise from an increased understanding of the interactions between radiation and matter, where Compton ...
Nicewonger, Daniel
core +1 more source
Molecular Oncology, EarlyView.This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau +9 more
wiley +1 more source
Proton therapy- the modality of choice for future radiation therapy management of Prostate Cancer?
Technical Innovations & Patient Support in Radiation Oncology, 2019 Background: Proton Therapy (PR) is an emerging treatment for prostate cancer (Pca) patients. However, limited and conflicting data exists regarding its ability to result in fewer bladder and rectal toxicities compared to Photon Therapy (PT), as well as ...
Sophie Mangan, Michelle Leech
doaj
Thoracic Cancer, 2019 Background The purpose of the present study was to retrospectively evaluate the safety and efficacy of proton beam therapy (PBT) in patients with second primary lung cancer after lung resection.
Takashi Ono +7 more
doaj +1 more source
Eccrine poromatosis following chemotherapy and radiation therapy [PDF]
, 2019 Eccrine poroma presents as a single, symptomless erythematous papule in areas with a high density of eccrine sweat glands. Although rare, eccrine poromas can present as multiple lesions, otherwise known as eccrine poromatosis.
Chiu, Melvin, Kim, Gene, Nguyen, Khoa
core
Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
Technical Innovations & Patient Support in Radiation Oncology, 2018 This guideline details the European Higher Education Area Levels 7 and 8 Postgraduate benchmarking document for Radiation TherapisTs (RTTs). The purpose of this benchmarking document is to assist higher education institutes in the development of ...
Mary Coffey, Michelle Leech
doaj