Results 71 to 80 of about 634,083 (315)

Potential benefit of scanned proton beam versus photons as adjuvant radiation therapy in breast cancer

, 2015
Purpose: To investigate the feasibility of using scanned proton beams as adjuvant radiation therapy for breast cancer. Long-term cardiopulmonary complications may worsen the quality of life and reduce the positive contribution of radiation therapy, which
Josefsson, Dan,, Dohlmar, Frida, Flejmer, Anna M.,, Dasu, Alexandru, Dohlmar, Frida,, Flejmer, Anna M., Witt Nyström, Petra,, Dasu, Alexandru,, Witt Nyström, Petra, Josefsson, Dan   +9 more
core   +1 more source

Mean Heart Dose Is an Inadequate Surrogate for Left Anterior Descending Coronary Artery Dose and the Risk of Major Adverse Cardiac Events in Lung Cancer Radiation Therapy

, 2021
Purpose: Mean heart dose (MHD) over 10 Gy and left anterior descending (LAD) coronary artery volume (V) receiving 15 Gy (V15Gy) greater than 10% can significantly increase the risk of major adverse cardiac events (MACE) in patients with non-small cell ...
Aerts, Hugo J. W. L., Tamarappoo, Balaji K., Chaunzwa, Tafadzwa L., Mak, Raymond H., Atkins, Katelyn M., Baldini, Elizabeth H., Hoffmann, Udo, Nohria, Anju, Bitterman, Danielle S., Kozono, David E.   +9 more
core   +1 more source

miR-142-3p attenuates breast cancer stem cell characteristics and decreases radioresistance in vitro

Tumor Biology, 2018
Effectively targeting cancer stem cells, a subpopulation of tumorigenic, aggressive, and radioresistant cells, holds therapeutic promise. However, the effects of the microRNA miR-142-3p, a small endogenous regulator of gene expression on breast cancer ...
Fabian M Troschel, Nicolas Böhly, Katrin Borrmann, Timo Braun, Alexander Schwickert, Ludwig Kiesel, Hans Theodor Eich, Martin Götte, Burkhard Greve   +8 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Journal of Proton Therapy: Call for Papers

, 2015
Journal of Proton Therapy (JPT) is an international open access, peer-reviewed journal, which publishes original research, technical reports, reviews, case reports, editorials, and other materials on proton therapy with focus on radiation oncology ...
Proton Therapy, Journal of
core  

A review on photoneutrons characteristics in radiation therapy with high-energy photon beams

, 2010
In radiation therapy with high-energy photon beams (E[[ce:hsp sp="0.25"/]]>[[ce:hsp sp="0.25"/]]10[[ce:hsp sp="0.25"/]]MeV) neutrons are generated mainly in linacs head thorough (γ,n) interactions of photons with nuclei of high atomic number materials ...
Mesbahi, Asghar; Radiation Therapy Department, Imam Hospital, Tabriz University of Medical Sciences, Tabriz, Iran; Medical Physics Department, Medical School, Tabriz University of Medical Sciences, Tabriz, Iran, Naseri, Alireza; Radiation Therapy Department, Imam Hospital, Tabriz University of Medical Sciences, Tabriz, Iran   +1 more
core   +1 more source

Workforce planning, staffing and education requirements for radiation therapists (RTTs) in the European Union as part of the EU-REST project

Technical Innovations & Patient Support in Radiation Oncology
Background: The European Society for Radiotherapy and Oncology (ESTRO), together with other relevant European societies, took part in a recent project focused on workforce availability, education and staffing in medical applications of radiation in the ...
Mary Coffey, Michelle Leech
doaj   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Volumetric modulated arc therapy for spine SBRT patients to reduce treatment time and intrafractional motion

, 2015
Volumetric modulated arc therapy (VMAT) is an efficient technique to reduce the treatment time and intrafractional motion to treat spine patients presented with severe back pain. Five patients treated with spine stereotactic body radiation therapy (SBRT)
Huang, Ke; Department of Radiation Oncology, Georgia Regents University, Augusta, Georgia, Dalton, Allison; Department of Radiation Oncology, Georgia Regents University, Augusta, Georgia, Amoush, Ahmad; Department of Radiation Oncology, Georgia Regents University, Augusta, Georgia, Rabatic, Bryan; Department of Radiation Oncology, Georgia Regents University, Augusta, Georgia, Al-Basheer, Ahmad; Department of Radiation Oncology, Georgia Regents University, Augusta, Georgia   +4 more
core   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source