Results 81 to 90 of about 6,899,989 (399)
Clinical results of proton beam therapy for twenty older patients with esophageal cancer
Radiology and Oncology, 2015 Background. In an aging society, increasing number of older patients are diagnosed with esophageal cancer. The purpose of this study was to assess the clinical efficacy and safety of proton beam therapy for older patients with esophageal cancer.
Ono Takashi +10 more
doaj +1 more source
Fractionation in radiation therapy
International Journal of Radiation Oncology*Biology*Physics, 1987 Variations in schedule from the usual 200 cGy daily, 5 days a week, for six or seven weeks, will be reviewed with both the radiobiological basis and clinical results so far. Hyperfractionated schedules (e.g., 1.15 Gy b.i.d. for 7 weeks) have given lo-15% better local control than the conventional 7-week schedule, with no extra late effects, both in ...
openaire +2 more sources
TRPM8 levels determine tumor vulnerability to channel agonists
Molecular Oncology, EarlyView.TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo +18 more
wiley +1 more source
CRISPRi-based radiation modifier screen identifies long non-coding RNA therapeutic targets in glioma. [PDF]
, 2020 BackgroundLong non-coding RNAs (lncRNAs) exhibit highly cell type-specific expression and function, making this class of transcript attractive for targeted cancer therapy.
Akeson, Mark +20 more
core +1 more source
Antioxidants and Radiation Therapy [PDF]
The Journal of Nutrition, 2004 The American Cancer Society estimates 1,368,050 new cancer cases in 2004 and 536,700 deaths from the disease. Although cancer rates for different sites vary widely, the 5-year relative survival rate for all cancers combined is estimated at 63%. Among the many possible causes of cancer, reactive oxygen species (ROS) have been implicated in the onset and
openaire +3 more sources
Ablative radiation therapy for locally advanced pancreatic cancer: techniques and results
Radiation Oncology, 2019 Standard doses of conventionally fractionated radiation have had minimal to no impact on the survival duration of patients with locally advanced unresectable pancreatic cancer (LAPC).
M. Reyngold, P. Parikh, C. Crane
semanticscholar +1 more source
Molecular Oncology, EarlyView.Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed +8 more
wiley +1 more source
miR-142-3p attenuates breast cancer stem cell characteristics and decreases radioresistance in vitro
Tumor Biology, 2018 Effectively targeting cancer stem cells, a subpopulation of tumorigenic, aggressive, and radioresistant cells, holds therapeutic promise. However, the effects of the microRNA miR-142-3p, a small endogenous regulator of gene expression on breast cancer ...
Fabian M Troschel +8 more
doaj +1 more source
A statistical shape model for deformable surface [PDF]
, 2010 This short paper presents a deformable surface registration scheme which is based on the statistical shape modelling technique. The method consists of two major processing stages, model building and model fitting.
Matuszewski, Bogdan +2 more
core
Toxic Epidermal Necrolysis after Pemetrexed and Cisplatin for Non-Small Cell Lung Cancer in a Patient with Sharp Syndrome [PDF]
, 2012 Background: Pemetrexed is an antifolate drug approved for maintenance and second-line therapy, and, in combination with cisplatin, for first-line treatment of advanced nonsquamous non-small cell lung cancer.
Aguiar D +28 more
core +1 more source