Results 81 to 90 of about 6,862,572 (354)

miR-142-3p attenuates breast cancer stem cell characteristics and decreases radioresistance in vitro

open access: yesTumor Biology, 2018
Effectively targeting cancer stem cells, a subpopulation of tumorigenic, aggressive, and radioresistant cells, holds therapeutic promise. However, the effects of the microRNA miR-142-3p, a small endogenous regulator of gene expression on breast cancer ...
Fabian M Troschel   +8 more
doaj   +1 more source

Fractionation in radiation therapy

open access: yesInternational Journal of Radiation Oncology*Biology*Physics, 1987
Variations in schedule from the usual 200 cGy daily, 5 days a week, for six or seven weeks, will be reviewed with both the radiobiological basis and clinical results so far. Hyperfractionated schedules (e.g., 1.15 Gy b.i.d. for 7 weeks) have given lo-15% better local control than the conventional 7-week schedule, with no extra late effects, both in ...
openaire   +2 more sources

Antioxidants and Radiation Therapy [PDF]

open access: yesThe Journal of Nutrition, 2004
The American Cancer Society estimates 1,368,050 new cancer cases in 2004 and 536,700 deaths from the disease. Although cancer rates for different sites vary widely, the 5-year relative survival rate for all cancers combined is estimated at 63%. Among the many possible causes of cancer, reactive oxygen species (ROS) have been implicated in the onset and
openaire   +3 more sources

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

open access: yesMolecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon   +13 more
wiley   +1 more source

The scenario-based generalization of radiation therapy margins

open access: yes, 2015
We give a scenario-based treatment plan optimization formulation that is equivalent to planning with geometric margins if the scenario doses are calculated using the static dose cloud approximation.
Bokrantz, Rasmus, Fredriksson, Albin
core   +1 more source

Pro-con of proton: Dosimetric advantages of intensity-modulation over passive scatter for thoracic malignancies

open access: yesTechnical Innovations & Patient Support in Radiation Oncology, 2020
The use of passively scattered proton therapy (PSPT) or intensity modulated proton therapy (IMPT) opens the potential for dose escalation or critical structure sparing in thoracic malignancies.
Ang Wei Jie, Laure Marignol
doaj   +1 more source

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

open access: yesMolecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim   +11 more
wiley   +1 more source

Efficacy and Safety Of Radiation Synovectomy with Yttrium-90 [PDF]

open access: yes, 1993
In this long term retrospective study of radiation synovectomy with Yttrium-90 (Y90), we evaluated the results of 164 applications in 82 patients with RA, OA with synovitis, ankylosing spondylitis and psoriatic arthritis.
Bozzone, P.   +4 more
core  

Psoriasis Vulgaris Successfully Treated with Goeckerman Treatment at Home: A Patient and Physician's Experience. [PDF]

open access: yes, 2020
Goeckerman therapy is a highly effective treatment regimen for moderate-to-severe psoriasis. It involves regular exposure to ultraviolet B radiation and the application of crude coal tar.
Bhutani, Tina   +5 more
core  

Ablative radiation therapy for locally advanced pancreatic cancer: techniques and results

open access: yesRadiation Oncology, 2019
Standard doses of conventionally fractionated radiation have had minimal to no impact on the survival duration of patients with locally advanced unresectable pancreatic cancer (LAPC).
M. Reyngold, P. Parikh, C. Crane
semanticscholar   +1 more source

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