Results 61 to 70 of about 786,111 (330)

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Propiedades termoluminiscentes de una albita de minas Geraes (Brasil)

Boletín de la Sociedad Española de Cerámica y Vidrio, 2004
Albite sodium feldspar is studied by thermoluminescent methods using the blue region of the spectra (circa 400nm) and the possible uses as a dosimeter are explored.
García-Guinea, J., Pitalua, F., Correcher, V., Sánchez-Muñoz, L., Valle-Fuentes, F. J., Lopez-Arce, P.   +5 more
doaj  

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

ComFC mediates transport and handling of single-stranded DNA during natural transformation

Nature Communications, 2022
The ComFC protein is essential for natural transformation, a process that plays a major role in the spread of antibiotic resistance genes. Here the authors show that ComFC is a membrane-associated protein that participates in the transport of DNA through
Prashant P. Damke, Louisa Celma, Sumedha M. Kondekar, Anne Marie Di Guilmi, Stéphanie Marsin, Jordane Dépagne, Xavier Veaute, Pierre Legrand, Hélène Walbott, Julien Vercruyssen, Raphaël Guérois, Sophie Quevillon-Cheruel, J. Pablo Radicella   +12 more
doaj   +1 more source

Electromagnetic Radiation* [PDF]

, 1999
Electromagnetic radiation, commonly referred to as light, underpins all spectroscopic techniques, ranging from the highly energetic gamma rays, through x-rays, ultraviolet, visible, infrared, microwaves to the low-energy radio waves. The principles of wave- and particle-like behaviour determine the nature of the radiation and its interaction with ...
openaire   +4 more sources

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Constraints on power law and exponential models in f(Q) gravity

Physics Letters B
In this paper, we observationally test the f(Q) gravity model at both background and perturbation levels using Pantheon+, Hubble measurements, and Redshift Space Distortion Data.
Dalale Mhamdi, Farida Bargach, Safae Dahmani, Amine Bouali, Taoufik Ouali   +4 more
doaj   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

A comparative analysis of the NaI detector response function using GAMOS and FLUKA Monte Carlo simulations

Nuclear Analysis
This work aims to study the response function of a 2″×2″ NaI(Tl) scintillation detector using Monte Carlo simulations. A precise mathematical model of the NaI(Tl) scintillator was developed using both FLUKA and GAMOS Monte Carlo simulation software.
A. Arectout, H. Boukhal, E. Chakir, M. Jarmouni, M. Assalmi, T. El Ghalbzouri, O.E. Belhaj, Mohamed Drissi El-Bouzaidi, A. Nouayti, I. Zidouh, H. El Yaakoubi   +10 more
doaj   +1 more source

The discrete ordinate method for angular flux calculations in slab geometry

Heliyon, 2019
In many deterministic methods, concerning the resolution of the neutron transport equation, a more global and practical representation of the angular flux is needed to provide us with useful and complete information on the neutron population in a reactor
M. Lahdour, T. El Bardouni, M. Mohammed, S. El Ouahdani   +3 more
doaj   +1 more source