Results 71 to 80 of about 786,111 (330)

Advanced dosimetry systems for the space transport and space station [PDF]

open access: yes, 1972
Advanced dosimetry system concepts are described that will provide automated and instantaneous measurement of dose and particle spectra. Systems are proposed for measuring dose rate from cosmic radiation background to greater than 3600 rads/hr.
Clark, B. C.   +2 more
core   +1 more source

An interpretation for the entropy of a black hole

open access: yes, 2011
We investigate the meaning of the entropy carried away by Hawking radiations from a black hole. We propose that the entropy for a black hole measures the uncertainty of the information about the black hole forming matter's precollapsed configurations ...
A. Strominger   +29 more
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Mitotic dynamics of the nuclear lamina behind the scenes of chromosome separation

open access: yesCommunications Biology
The regulation of mitosis is essential for genome inheritance and stability. In mammals, many cellular ultrastructures, including the nuclear envelope, undergo significant morphological changes to facilitate chromosome separation.
Julien Picotto   +2 more
doaj   +1 more source

Positron-based attenuation correction for Positron Emission Tomography data using MCNP6 code

open access: yesJournal of Radiation Research and Applied Sciences, 2016
This paper presents the Monte Carlo simulation of the attenuation correction for Positron Emission Tomography (PET) data using MCNP6 code. Two attenuation correction maps have been generated, one for correcting the attenuation effect in a homogeneous ...
M. Saeed   +6 more
doaj   +1 more source

Experimental active and passive dosimetry systems for the NASA Skylab program [PDF]

open access: yes, 1972
Active and passive dosimetry instrumentation to measure absorbed dose, charged particle spectra, and linear energy transfer spectra inside the command module and orbital workshop on the Skylab program were developed and tested.
Ainsworth, G. C.   +2 more
core   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Influence of Individual Radiosensitivity on the Hormesis Phenomenon: Toward a Mechanistic Explanation Based on the Nucleoshuttling of ATM Protein

open access: yesDose-Response, 2020
Hormesis is a low-dose phenomenon that has been reported to occur, to different extents, in animals, plants, and microorganisms. However, a review of the literature shows that only a few reports describe it in humans.
Clément Devic   +3 more
doaj   +1 more source

Space-time Structure of Initial Parton Production in Ultrarelativistic Heavy Ion Collisions

open access: yes, 1993
The space and time evolution of initial parton production in ultrarelativistic heavy ion collisions is investigated within the framework of perturbative QCD which includes both initial and final state radiations.
A. Capella   +44 more
core   +2 more sources

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

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