Results 71 to 80 of about 2,417,103 (345)
ComFC mediates transport and handling of single-stranded DNA during natural transformation
Nature Communications, 2022 The ComFC protein is essential for natural transformation, a process that plays a major role in the spread of antibiotic resistance genes. Here the authors show that ComFC is a membrane-associated protein that participates in the transport of DNA through
Prashant P. Damke +12 more
doaj +1 more source
Ancient River Inference Explains Exceptional Oriental Freshwater Mussel Radiations
Scientific Reports, 2017 The concept of long-lived (ancient) lakes has had a great influence on the development of evolutionary biogeography. According to this insight, a number of lakes on Earth have existed for several million years (e.g., Baikal and Tanganyika) and represent ...
I. Bolotov +10 more
semanticscholar +1 more source
Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence
Molecular Oncology, EarlyView.The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova +18 more
wiley +1 more source
Positron-based attenuation correction for Positron Emission Tomography data using MCNP6 code
Journal of Radiation Research and Applied Sciences, 2016 This paper presents the Monte Carlo simulation of the attenuation correction for Positron Emission Tomography (PET) data using MCNP6 code. Two attenuation correction maps have been generated, one for correcting the attenuation effect in a homogeneous ...
M. Saeed +6 more
doaj +1 more source
Evolutionary radiations in the species-rich mountain genus Saxifraga L.
BMC Evolutionary Biology, 2017 BackgroundA large number of taxa have undergone evolutionary radiations in mountainous areas, rendering alpine systems particularly suitable to study the extrinsic and intrinsic factors that have shaped diversification patterns in plants.
J. Ebersbach +3 more
semanticscholar +1 more source
Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren +16 more
wiley +1 more source
Results in Physics, 2018 The MNSR is a pool type research reactor, which is difficult to model because of the importance of neutron leakage. The aim of this study is to evaluate a 2-D transport model for the reactor compatible with the latest release of the DRAGON code and 3-D ...
Jamal Al Zain +4 more
doaj
Convergence of gut microbiotas in the adaptive radiations of African cichlid fishes
The ISME Journal, 2017 Ecoevolutionary dynamics of the gut microbiota at the macroscale level, that is, in across-species comparisons, are largely driven by ecological variables and host genotype.
L. Baldo +5 more
semanticscholar +1 more source
TRPM8 levels determine tumor vulnerability to channel agonists
Molecular Oncology, EarlyView.TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo +18 more
wiley +1 more source