Results 261 to 270 of about 4,601,498 (378)

Thermally-Induced in Situ Synthesisof Ethylene-Linked Viologen Ionic Radical Polymers for PhotocatalyticCO₂ Cycloaddition

Shuo Wang (143908), Qing Shi (161182), Yulong Lin (11611510), Juan Chen (61123), Yunjie Mao (10258477), Xiaomeng Bai (15473473), Jinfeng Yu (6430805), Yanli Gai (1797142), Zhouyang Long (1783435), Guojian Chen (1543039)   +9 more
openalex   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Robotic assisted radical prostatectomy improves biochemical recurrence-free survival: The PROCA-life study. [PDF]

J Robot Surg
Knutsen T, Aarsaether E, Wilsgaard T, Støyten M, Stikbakke E, Richardsen E, Larsen M, Thune I, Haugnes HS.   +8 more
europepmc   +1 more source

Educating nurses: A call for radical transformation

, 2011
S. Izumi
semanticscholar   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Heterogeneous collaboration patterns and radical innovation performance-a data-driven analysis from specialized, refined, differentiated, and innovative enterprises. [PDF]

Sci Rep
Zhang L, Zhang Y, Huang Z, Li H.
europepmc   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Light-Induced Orthogonal Reactivity of Photoinitiators from One-Electron Reduction to Nanocomposites. [PDF]

Angew Chem Int Ed Engl
Schmallegger M, Wiech M, Gescheidt G.
europepmc   +1 more source

El imaginario en Cornelius Castoriadis y Gilbert Durand. Un distanciamiento radical [PDF]

Ignacio Riffo-Pavón, Enrique Carretero
openalex   +1 more source