This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu+12 more
wiley +1 more source
Perioperative Outcomes After Radical Nephrectomy with Inferior Vena Cava Thrombectomy. [PDF]
Pyrgidis N+6 more
europepmc +1 more source
Comment on "Peripheral T Lymphocyte Predicts the Prognosis of Gastric Cancer Patients Undergoing Radical Gastrectomy: A Multicenter Retrospective Cohort Study" [Response to Letter]. [PDF]
Xiao H, Luo J.
europepmc +1 more source
Understanding and measuring mechanical signals in the tumor stroma
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz+3 more
wiley +1 more source
CoO<sub>x</sub> clusters-decorated IrO<sub>2</sub> electrocatalyst activates NO<sub>3</sub><sup>-</sup> mediator for benzylic C-H activation. [PDF]
Mi Z+7 more
europepmc +1 more source
Phenyl Radical-Mediated Fluorogenic Cyclization for Specific Detection of Peroxynitrite. [PDF]
Grzelakowska A+2 more
europepmc +1 more source
3-Center-3-Electron σ-Adduct Enables Silyl Radical Transfer below the Minimum Barrier for Silyl Radical Formation. [PDF]
Qiu Z+9 more
europepmc +1 more source
Synthesis of trypsin-protected CsPbCl<sub>3</sub> fluorescent nanocrystals for hydroxyl radical sensing. [PDF]
Kailasa SK+6 more
europepmc +1 more source
The two-stage approach for treating combined pulmonary and hepatic hydatid cyst: A case report. [PDF]
Mohamed G+4 more
europepmc +1 more source