Results 91 to 100 of about 30,338 (309)

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Ontology, ‘hauntology’ and the ‘turn’ that keeps anthropology turning [PDF]

open access: yes, 2016
© 2016, © The Author(s) 2016. Twentieth-century anthropology has been operating with the assumption of one nature and many cultures, one reality experienced and lived in many different ways. Its primary job, therefore, has been to render the otherness of
Argyrou, Vassos
core   +1 more source

The Radical Desire for Life. From Immanence in Michel Henry to Alterity in Saint Augutine

open access: yesPensamiento. Revista de Investigación e Información Filosófica, 2013
The principal purpose of this text is to show that Michel Henry’s radicalization of phenomenology conduces to a problematic interpretation of the world and human desire, and to proposea solution to the problem from the philosophy of Augustine of Hippo ...
Diego I. Rosales Meana
doaj  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

The Literary Labour of Ants

open access: yesHumanimalia
This essay considers the literary labour carried out by ants in Daniel Sada’s Porque parece mentira la verdad nunca se sabe (1999), considered one of the most significant works of Mexican literature in the last decade of the twentieth century. This essay
Sergio Gutiérrez Negrón
doaj   +1 more source

Let Go of Laqueur: Towards New Histories of the Sexed Body

open access: yesEugesta, 2019
Once upon a time, the body had no sex. This is the story that has long been told about the history of the sexed body in “the West” under the influence of Thomas Laqueur’s book Making Sex: Body and Gender from the Greeks to Freud, published in 1990.
Brooke Holmes
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Afterword [PDF]

open access: yes, 2008
Book description: Luce Irigaray: Teaching explores ways to confront new issues in education. Three essays by Irigaray herself present the outcomes of her own experiments in this area and develop proposals for teaching people how to coexist in difference,
Worton, M.
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

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