Results 121 to 130 of about 421 (264)

The Lesson of Sleeping Beauty: Person-Centred Care for the Unconscious, Unresponsive ICU Patient in the Face of Levinas' Radical Alterity. [PDF]

Nurs Philos
Clement T, Zeillinger PA, Mayer H, McCormack B.   +3 more
europepmc   +1 more source

Beyond continental and African philosophies of personhood, healthcare and difference. [PDF]

Nurs Philos, 2022
Imafidon E.
europepmc   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Dwelling with limits: the work of love in participatory research

Fennia: International Journal of Geography
In this article, we examine some of the theoretical and methodological challenges facing Participatory Action Research (PAR), including the continued challenge of the silence of the subaltern, the re-subjugating power relations in many traditional ...
Raine Aiava, Noora Pyyry
doaj  

Ethical-Linguistic constitution of clinical subjectivities: a Lévinasian perspective. [PDF]

Philos Ethics Humanit Med
Pompilio CE, de Toledo França M.
europepmc   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Potent antioxidant and mitochondrial-protective effects of ATH434, a moderate affinity iron chaperone. [PDF]

J Biol Chem
Bailey DK, Nihlawi R, Bradbury MJ, Bond S, Kosman DJ.   +4 more
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

The temporal and embodied structure of the mineness sphere: some phenomenological ideas to frame mental health. [PDF]

Front Psychol
Sánchez CS.
europepmc   +1 more source