Results 251 to 260 of about 30,338 (309)

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

Apolipoprotein E in Alzheimer's disease: molecular insights and therapeutic opportunities. [PDF]

Mol Neurodegener
Belaidi AA, Bush AI, Ayton S.
europepmc   +1 more source

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Radical antegrade modular pancreatosplenectomy (RAMPS): does adrenalectomy alter outcomes?

HPB, 2022
Radical antegrade modular pancreatosplenectomy (RAMPS) has oncologic superiority compared to a standard distal pancreatectomy (DP). For tumors invading into the adrenal gland, a posterior RAMPS takes the left adrenal gland en bloc with the pancreas specimen.
Catherine H. Davis, Michael Spinrad, Toni Beninato, Amanda M. Laird, Miral S. Grandhi, Susan C. Pitt, Henry A. Pitt   +6 more
openaire   +2 more sources

Myocardial alterations due to free-radical generation

American Journal of Physiology-Heart and Circulatory Physiology, 1984
Oxygen-derived free radicals have been proposed as general mediators of tissue injury in a variety of disease states. Recent interest has focused on the possibility that free radicals may be involved in ischemic myocardial damage. However, the exact types of damage that result from myocardial exposure to free radicals remains to be established.
K P, Burton, J M, McCord, G, Ghai
openaire   +2 more sources

HISTOLOGICAL ALTERATIONS IN CAVERNOUS TISSUE AFTER RADICAL PROSTATECTOMY

Journal of Urology, 2005
Radical prostatectomy often results in erectile dysfunction because of lesions to the erectile nerves. In this study we evaluated histomorphological alterations in cavernous smooth muscle and collagen content after radical prostatectomy.A total of 19 patients between 57 and 69 years old with prostate adenocarcinoma and normal erectile function, as ...
Iacono F, Giannella R, Somma P, Manno G, Fusco F, Mirone V.   +5 more
openaire   +5 more sources

Free radical-induced alterations of myocardial membrane proteins

Archives of Biochemistry and Biophysics, 1991
Rat myocardial membranes exposed to the free radical-generating systems, Fe2+/ascorbate, Cu2+/t-butylhydro-peroxide, linoleic acid hydroperoxide, and soybean lipoxygenase (Type I) undergo lipid peroxidation. This is evidenced by the accumulation of thiobarbituric acid-reactive substances and the loss of both extractable phospholipids and their ...
N L, Parinandi, C W, Zwizinski, H H, Schmid   +2 more
openaire   +2 more sources

Alterations in free radical activity in aging Drosophila

Experimental Gerontology, 1994
Drosophila were examined to see if there is an increase in damage associated with free radical activity in older flies. The levels of superoxide radical and of lipid peroxides were higher in membrane samples from older flies. Also, in older Drosophila there was a significant decrease in membrane fluidity, as determined by fluorescence polarization, and
L, Shi, M, Sawada, U, Sester, J C, Carlson   +3 more
openaire   +2 more sources

Free Radical-Induced Alterations in Endothelial Cell Function

Journal of Surgical Research, 1994
Free radical-induced injury to the arterial wall has been implicated in the pathogenesis and progression of atherosclerosis. To model the in vitro effects of free radicals on endothelial cell function, protein and lipid synthesis were measured after exposing cells to a superoxide generating system of xanthine (X = 100 microM) and xanthine oxidase (XO =
R A, Kozar, B J, McKeone, H J, Pownall
openaire   +2 more sources

Social Anthropology, Radical Alterity And Culture

Canberra Anthropology, 1992
S'interrogeant sur la notion de « culture », l'A. critique certains des points de vue de Keesing concernant l'anthropologie sociale : la necessite de souligner les differences afin de mettre en evidence la construction culturelle dans un monde ou l'homogeneisation se developpe ; le concept anthropologique de culture a ete contamine par la pensee ...
openaire   +1 more source

Marked Gene Transcript Level Alterations Occur Early During Radical Prostatectomy

European Urology, 2008
Gene expression analyses have become an important approach to understand the biology of cancer. However, transcript level patterns and RNA quality could rapidly change in response to ischemic and mechanical stress. Studies have shown that this occurs both perioperatively and after surgical removal of organs.To better understand the relative importance ...
Thorsten, Schlomm, Esther, Näkel, Andreas, Lübke, Andreas, Buness, Felix K-H, Chun, Thomas, Steuber, Markus, Graefen, Ronald, Simon, Guido, Sauter, Annemarie, Poustka, Hartwig, Huland, Andreas, Erbersdobler, Holger, Sültmann, Olaf J C, Hellwinkel   +13 more
openaire   +2 more sources