Results 61 to 70 of about 421 (264)

Review of "The Essentialist Villain: On Leo Bersani" by Mikko Tuhkanen (State University of New York Press)

open access: yesLateral, 2018
Mikko Tuhkanen’s provocative and comprehensive study of the work of Leo Bersani deserves the status of a decisive and paradigm-shifting event in the field of critical theory. Bersani’s work, which has evolved over a period of over fifty years, emerges as
Patrick ffrench
doaj   +1 more source

From Dog Alterity to Canine Sublime: A Cross-Century Reading of Victorian Fiction

open access: yesCahiers Victoriens et Edouardiens, 2017
From Charles Dickens to Joseph Conrad dogs are omnipresent in Victorian novels. Many recent critical works have investigated the part they play, either within the confines of specific novels or against the enlarged context of Victorian culture. Reversing
Georges Letissier
doaj   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Masking the Systematic Violence Perpetuated By Liberalism Through the Concept of ‘Totalitarianism’

open access: yesPolitikon, 2016
Starting from the European conquest in 1492 which established the beginning of colonialism, going through the establishment of liberalism’s racial (‘social’) contract, and coming to present times of neocolonialism and neoliberalism, this paper ...
Ioana Cerasella Chis
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

De la estetización de la política a la comunidad desobrada.

open access: yesRevista de Estudios Sociales, 2010
This article shows that the notion of an “aesthetization of politics” entails much more than the mere translation of aesthetic criteria into politics. The task of thinking about a non-aesthetiziced political realm, therefore, demands even more radical ...
María del Rosario Acosta.   +1 more
doaj  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

La valeur des pauvres. Le pari sur l’argent comme médiateur du conflit social contemporain

open access: yesConfins, 2016
In contemporary Brazil, the urban periphery have two recent and dichotomous figurations: the cause of 'urban violence' that calls for more repression and the core of the 'development' which can turn poor people into "middle class". This essay argues that
Gabriel de Santis Feltran
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

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