Results 71 to 80 of about 30,338 (309)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

The King's many bodies: the self-deconstruction of law's hierarchy [PDF]

open access: yes, 2006
The article connects two strands of the recent sociolegal debate: (1) the empirical discovery of new forms of spontaneous law in die Course of globalization, and (2) the emergence of deconstructive theories of law that undermine the law's hierarchy.
Teubner, Gunther
core  

Traversing Racial Distance in Hip-hop Culture: The Ethics and Politics of Listening [PDF]

open access: yes, 2015
Hip-hop is often studied as a ‘political’ culture. Listeners, however, often contest the attachment of a political nature to hip-hop. After the ‘dilution’ of “real” hip-hop by record labels seeking to package the sound for mainstream consumption, is it ...
Ganesh, B
core   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

WRITING ON THE WALL: BENJAMIN, KAFKA, BORGES, AND THE CHINESE IMAGINARY

open access: yes452ºF, 2015
Using Kafka’s short story “The Great Wall of China” as a starting point, this essay examines the ways in which a dialectics of inclusion and exclusion, construction and destruction, have been deployed in discussions of identity and difference.
CARLOS ROJAS
doaj  

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Human rights and the law: the unbreachable gap between the ethics of justice and the efficacy of law [PDF]

open access: yes, 2012
This paper explores the structure of justice as the condition of ethical, inter-subjective responsibility. Taking a Levinasian perspective, this is a responsibility borne by the individual subject in a pre-foundational, proto-social proximity with the ...
Indaimo, Joseph A.
core  

Post-Symbolic Coloniality: The Metasimulacrum of Otherness in Digital Culture

open access: yesГалактика медиа: журнал медиа исследований
This article develops the concept of the metasimulacrum of otherness to analyze the structural transformations of difference in digital culture. Unlike traditional representations of otherness, the metasimulacrum reorganizes the very conditions of ...
Rastyam T. Aliev
doaj   +1 more source

Review of "The Essentialist Villain: On Leo Bersani" by Mikko Tuhkanen (State University of New York Press)

open access: yesLateral, 2018
Mikko Tuhkanen’s provocative and comprehensive study of the work of Leo Bersani deserves the status of a decisive and paradigm-shifting event in the field of critical theory. Bersani’s work, which has evolved over a period of over fifty years, emerges as
Patrick ffrench
doaj   +1 more source

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