Results 71 to 80 of about 421 (264)
The Radical Desire for Life. From Immanence in Michel Henry to Alterity in Saint Augutine
Pensamiento. Revista de Investigación e Información Filosófica, 2013 The principal purpose of this text is to show that Michel Henry’s radicalization of phenomenology conduces to a problematic interpretation of the world and human desire, and to proposea solution to the problem from the philosophy of Augustine of Hippo ...
Diego I. Rosales Meana
doaj
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
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HumanimaliaThis essay considers the literary labour carried out by ants in Daniel Sada’s Porque parece mentira la verdad nunca se sabe (1999), considered one of the most significant works of Mexican literature in the last decade of the twentieth century. This essay
Sergio Gutiérrez Negrón
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Let Go of Laqueur: Towards New Histories of the Sexed Body
Eugesta, 2019 Once upon a time, the body had no sex. This is the story that has long been told about the history of the sexed body in “the West” under the influence of Thomas Laqueur’s book Making Sex: Body and Gender from the Greeks to Freud, published in 1990.
Brooke Holmes
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FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
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FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
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SCIENCE AND TRANSCENDENCE: WESTPHAL, DERRIDA, AND RESPONSIBILITY
Zygon, 2012 . On the naive reading, “radical social constructivism” would be the result of “deconstructing” science. Science would simply be a contingent construction in accordance with social determinants.
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Somatics and phenomenological psychopathology: a mental health proposal. [PDF]
Theor Med Bioeth, 2023 Sánchez Sánchez C.
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Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
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Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
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