Results 21 to 30 of about 18,972 (226)

Renal tumor biopsy in patients with cT1b-T4-M0 disease susceptible to radical nephrectomy: analysis of safety, accuracy and clinical impact on definitive management

Scandinavian Journal of Urology, 2022
Purpose Renal tumor biopsy was provided in patients candidate to radical nephrectomy for a renal mass ≥4 cm, to evaluate treatment deviation. Methods Between 2008 and 2017, 102 patients with a solid renal mass ≥4 cm with no distant metastases underwent ...
Sebastiano Nazzani, Carlotta Zaborra, Davide Biasoni, Mario Catanzaro, Alberto Macchi, Silvia Stagni, Antonio Tesone, Tullio Torelli, Rodolfo Lanocita, Tommaso Cascella, Carlo Morosi, Carlo Spreafico, Maurizio Colecchia, Alfonso Marchianò, Emanuele Montanari, Roberto Salvioni, Nicola Nicolai   +16 more
doaj   +1 more source

Open Partial Nephrectomy in Renal Cancer: A Feasible Gold Standard Technique in All Hospitals

Advances in Urology, 2008
Introduction. Partial nephrectomy (PN) is playing an increasingly important role in localized renal cell carcinoma (RCC) as a true alternative to radical nephrectomy.
J. M. Cozar, M. Tallada
doaj   +1 more source

Significance of Charlson co-morbidity index as predictive factor for post-op complications after radical nephrectomy

Journal of the Pakistan Medical Association
The current study planned to explore the correlation between an elevated Charlson Comorbidity Index score and post-operative complications following radical nephrectomy in patients with renal cell carcinoma.
Nazish Mughal, Naveed Ahmed Mahar, Usama Bin Shaheen, Harris Hassan Qureshi, Naseem Akhtar, Sara Rasheed Kalwar, Altaf Hashmi   +6 more
doaj   +1 more source

Robot-assisted partial nephrectomy in contemporary practice

Frontiers in Oncology, 2013
Laparoscopic renal surgery is associated with reduced blood loss, shorter hospital stay, enhanced cosmesis, and more rapid convalescence relative to open renal surgery.
Youssef S. Tanagho, Sam B. Bhayani, Robert S. Figenshau   +2 more
doaj   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Targeting the ATX‐LPA Axis Overcomes TKI Resistance and Immunosuppression in Renal Cell Carcinoma via Dual Inhibition of AKT/mTOR and TBK1/IRF3 Pathways

Advanced Science, EarlyView.
ABSTRACT Background Therapeutic resistance limits durable survival in advanced/metastatic renal cell carcinoma (RCC) treated with first‐line tyrosine kinase inhibitor (TKI) plus immune checkpoint inhibitor (ICI). We sought to define key resistance drivers and actionable targets.
Jinchen Luo, Hansen Lin, Haoqian Feng, Lei Tan, Xi Liu, Yong Huang, Junjie Cen, Jiajie Chen, Xinwei Zhou, Mingjie Lin, Wuyuan Liao, Zheyu Ai, Minyu Chen, Yinghan Wang, Wei Chen, Junhang Luo, Yanping Liang   +16 more
wiley   +1 more source

Correlation of percentage changes in platelet counts with recurrence rate following radical nephrectomy

Indian Journal of Urology, 2010
Objectives : To categorize and correlate percentage changes in platelets counts - an objective approach with recurrence rate following radical nephrectomy. Materials and Methods : All consecutive patients who had radical nephrectomy for localized renal
A Patel, R Bhavan, B Somani, G Nabi
doaj   +1 more source

Pathological Copper Overload Reprograms SOD1 Activation via COMMD1 to Promote Senescence and Fibrosis

Advanced Science, EarlyView.
This study uncovers a previously unrecognized copper‐COMMD1‐SOD1 regulatory axis, revealing that pathological copper overload paradoxically suppresses SOD1 activity by promoting COMMD1‐dependent disruption of SOD1 homodimerization. These findings redefine the regulatory role of copper in SOD1 biology and provide novel mechanistic insight into the ...
Yuqing Liu, Jing Liu, Wenqian Zhou, Yangyang Niu, Yan Zheng, Yiguo Liu, Yingying Zhang, Chen Yu   +7 more
wiley   +1 more source

NEW BASELINE GLOMERULAR FILTRATION RATE ESTIMATION AS A GUIDANCE FOR NEPHRECTOMY STRATEGY IN LOCALIZED RENAL CELL CARCINOMA

Jurnal Urologi Indonesia, 2023
Objective: This literature review aims to explain the role of nephrectomy in the treatment of localized RCC and its effects on postoperative renal function, as well as the role of the new baseline glomerular filtration rate (NBGFR) estimation method in ...
Muhamad Abi Salman Aziz, Achmad Fayyad Mas`udi, Anny Setijo Rahaju, Linda Dewanti   +3 more
doaj   +1 more source

ANGPTL4 Exacerbates Renal Injury in Diabetic Kidney Disease by Impairing Podocyte Lipophagy via Compromised Lysosomal Degradative Function

Advanced Science, EarlyView.
In diabetic kidney disease, elevated podocyte ANGPTL4 is linked to reduced TFEB nuclear localization and compromised lysosomal degradative function. These changes impair podocyte lipophagy and promote lipid‐droplet accumulation and podocyte injury, which may contribute to renal injury progression.
Xiaojing Liu, Shimin Jiang, Zhenkun Yang, Shunlai Shang, Jiayi Li, Guming Zou, Cheng Zhou, Wenge Li   +7 more
wiley   +1 more source