Results 31 to 40 of about 793,655 (239)

Open Partial Nephrectomy in Renal Cancer: A Feasible Gold Standard Technique in All Hospitals

open access: yesAdvances in Urology, 2008
Introduction. Partial nephrectomy (PN) is playing an increasingly important role in localized renal cell carcinoma (RCC) as a true alternative to radical nephrectomy.
J. M. Cozar, M. Tallada
doaj   +1 more source

Laparoscopic Partial Nephrectomy

open access: yes, 2015
Patients with renal tumors
Hasan Çetin, Ender Özden
core   +1 more source

Compensatory Mitophagy via NEDD4/HIF‐1α/BNIP3 Pathway Restrains EndMT and Renal Allograft Interstitial Fibrosis Induced by TNFα

open access: yesAdvanced Science, EarlyView.
The role of TNFα in the process of renal allograft interstitial fibrosis is complex and multifaceted. As it can promote renal allograft interstitial fibrosis by inducing mitochondrial dysfunction and EndMT, and also mediating compensatory mitophagy through the NEDD4–HIF‐1α–BNIP3 pathway, which clears damaged mitochondria and inhibits EndMT, thereby ...
Dengyuan Feng   +15 more
wiley   +1 more source

Comparison of patients managed by radical nephrectomy and partial radical nephrectomy.

open access: yes, 2015
Comparison of patients managed by radical nephrectomy and partial radical nephrectomy.
Tae Sun Kim (830411)   +10 more
core   +1 more source

Robot-assisted partial nephrectomy in contemporary practice

open access: yesFrontiers in Oncology, 2013
Laparoscopic renal surgery is associated with reduced blood loss, shorter hospital stay, enhanced cosmesis, and more rapid convalescence relative to open renal surgery.
Youssef S. Tanagho   +2 more
doaj   +1 more source

ANGPTL4 Exacerbates Renal Injury in Diabetic Kidney Disease by Impairing Podocyte Lipophagy via Compromised Lysosomal Degradative Function

open access: yesAdvanced Science, EarlyView.
In diabetic kidney disease, elevated podocyte ANGPTL4 is linked to reduced TFEB nuclear localization and compromised lysosomal degradative function. These changes impair podocyte lipophagy and promote lipid‐droplet accumulation and podocyte injury, which may contribute to renal injury progression.
Xiaojing Liu   +7 more
wiley   +1 more source

Renal Tubular Epithelial CRLF1 Interacts With ITGB1 to Accelerate Fibrosis During the Transition From AKI to CKD

open access: yesAdvanced Science, EarlyView.
During renal fibrosis, SMAD3 acts as a transcription factor for CRLF1, promoting its expression and secretion. CRLF1 then binds to ITGB1 via an autocrine mechanism, activating the PI3K‐AKT signaling pathway to mediate renal fibrosis. This accelerates the progression from AKI to CKD, highlighting the therapeutic potential of targeting CRLF1 for ...
Chunjie Wang   +8 more
wiley   +1 more source

Correlation of percentage changes in platelet counts with recurrence rate following radical nephrectomy

open access: yesIndian Journal of Urology, 2010
Objectives : To categorize and correlate percentage changes in platelets counts - an objective approach with recurrence rate following radical nephrectomy. Materials and Methods : All consecutive patients who had radical nephrectomy for localized renal
A Patel, R Bhavan, B Somani, G Nabi
doaj   +1 more source

NEW BASELINE GLOMERULAR FILTRATION RATE ESTIMATION AS A GUIDANCE FOR NEPHRECTOMY STRATEGY IN LOCALIZED RENAL CELL CARCINOMA

open access: yesJurnal Urologi Indonesia, 2023
Objective: This literature review aims to explain the role of nephrectomy in the treatment of localized RCC and its effects on postoperative renal function, as well as the role of the new baseline glomerular filtration rate (NBGFR) estimation method in ...
Muhamad Abi Salman Aziz   +3 more
doaj   +1 more source

USP30‐Mediated Deubiquitination of PEX5 Suppresses Pexophagy to Drive Tubular Injury in Diabetic Kidney Disease

open access: yesAdvanced Science, EarlyView.
USP30 accumulation in diabetic renal tubular epithelial cells deubiquitinates PEX5, suppresses pexophagy, and drives dysfunctional peroxisome accumulation and tubular injury. USP30 depletion restores PEX5 ubiquitination and pexophagy, improves peroxisomal function, and alleviates tubular damage, highlighting USP30 as a therapeutic target in diabetic ...
Jia Li   +10 more
wiley   +1 more source

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