Results 81 to 90 of about 766,114 (261)

MECHANICAL PROPERTIES OF SERVOVITE FILMS FORMED IN DURING FRICTION AQUEOUS SOLUTIONS OF CARBOXYLIC ACIDS

open access: yesAdvanced Engineering Research, 2018
Introduction. The effect of the organic component nature in the systematic series of monocarboxylic acids on the tribological characteristics of the brass-steel friction pair in aqueous solutions is described.
V. E. Burlakova   +3 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Magnetosensitivity of Model Flavin–Tryptophan Radical Pairs in a Dynamic Protein Environment

open access: yesThe Journal of Physical Chemistry B
Light-induced radical pairs in cryptochrome proteins located in the retina are thought to be the receptors at the heart of the magnetic compass sense of migratory songbirds. Reliable simulations of the performance of such sensors face several fundamental challenges.
Benjamin, Philip L.   +3 more
openaire   +2 more sources

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Sensing of magnetic field effects in radical-pair reactions using a quantum sensor

open access: yesPhysical Review Research
Magnetic field effects (MFE) in certain chemical reactions have been well established in the last five decades and are attributed to the evolution of transient radical pairs whose spin dynamics are determined by local and external magnetic fields.
Deepak Khurana   +6 more
doaj   +1 more source

Cryptochrome magnetoreception: Time course of photoactivation from non-equilibrium coarse-grained molecular dynamics

open access: yesComputational and Structural Biotechnology Journal
Magnetoreception, the ability to sense magnetic fields, is widespread in animals but remains poorly understood. The leading model links this ability in migratory birds to the photo-activation of the protein cryptochrome.
Jessica L. Ramsay   +3 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Unveiling mechanistic patterns of copper-catalyzed radical bond formation through linear free energy relationship

open access: yesNature Communications
Copper-catalyzed radical transformations have seen extensive investigations over recent decades. Due to the complexity of controlling factors and the diversity of reaction components, accurately delineating the bond formation mechanisms—namely reductive ...
Guo-Xiong Xu   +8 more
doaj   +1 more source

Role of Kekul\'e and Non-Kekul\'e Structures in the Radical Character of Alternant Polycyclic Aromatic Hydrocarbons: A TAO-DFT Study

open access: yes, 2016
We investigate the role of Kekule and non-Kekule structures in the radical character of alternant polycyclic aromatic hydrocarbons (PAHs) using thermally-assisted-occupation density functional theory (TAO-DFT), an efficient electronic structure method ...
Chai, Jeng-Da, Yeh, Chia-Nan
core   +1 more source

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