Results 81 to 90 of about 1,225,901 (299)

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

«The inert homeland succumbs to continental centripetalism»: the Portuguese radical right and Portugal›s accession to the European Economic Community (1974-1986)*

Historia y Memoria
The Revolution of 25 April 1974 caused a rupture in how Portugal thought and saw itself in the world. One of the consequences of this transformation was the rapid decolonisation between that year and the next.
Bruno Madeira
doaj   +1 more source

Illusionism's discontent [PDF]

, 2016
Frankish positions his view, illusionism about qualia (a.k.a. eliminativist physicalism), in opposition to what he calls radical realism (dualism and neutral monism) and conservative realism (a.k.a. non-eliminativist physicalism). Against radical realism,
Katalin, Balog
core   +1 more source

Electoral competition in Europe’s new tripolar political space : class voting for the left, centre-right and radical right [PDF]

, 2017
In a growing number of countries, the two dominant political poles of the 20th century, the parties of the Left and the Centre-Right, are challenged by a third pole made up by the Radical Right.
Afonso, Arndt, Bale, Bornschier, Bornschier, Bornschier, Cochrane, der Brug, Evans, Franklin, Gingrich, Grunberg, Hooghe, Ivarsflaten, Katz, Kitschelt, Kitschelt, Kitschelt, Kriesi, Kriesi, Kriesi, Lange, Lefkofridi, Martin, Mudde, Mudde, Oesch, Oesch, Oesch, Oesch, Rovny   +30 more
core   +3 more sources

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Religious references in political campaigning: a comparative analysis of Latin America and Western Europe on social media

Frontiers in Political Science
The relationship between religion and politics is receiving increasing attention in political science, although the focus is often on voter attitudes.
Jakob Schwörer
doaj   +1 more source

Radical innovation: making the right bets [PDF]

, 2014
Report published by Advanced Institute of Management ResearchOur research reveals that organisations, here in the UK and elsewhere, must face up to the complex challenges associated with exploring and developing radical ideas and innovations if they ...
Bessant, John, Möslein, Kathrin, Neyer, Anne-Katrin, Piller, Frank, Stamm, Bettina von   +4 more
core  

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

The New Face of Jim Crow: Voter Suppression in America [PDF]

, 2006
The radical right wing in America has developed an array of subtle and overt methods to suppress voter registration and turnout. The methods are targeted to constituencies most likely to oppose right-wing causes and candidates: low-income families ...

core  

Misdevelopments, Pathologies, and Normative Revolutions: Normative Reconstruction as Method of Critical Theory [PDF]

, 2015
In this article I argue that the method of normative reconstruction underlying Freedom's Right undermines Critical Theory's aspiration to be a force that is unreservedly critical and progressive. I start out by giving a brief account of the four premises
Allen A., Geuss R., Habermas J., Honneth A., Honneth A., Honneth A., Honneth A., Honneth A., Honneth A., Jörg Schaub, Packer G., Rousseau J.-J., Williams B.   +12 more
core   +1 more source