The Emerging Role of Peroxyacetic Acid in Water and Wastewater Treatment: Degradation of Pharmaceuticals, Microplastics, and Other Micropollutants. [PDF]
Zawiślak P +4 more
europepmc +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Tetra-substituted BDPA radicals <i>via</i> click-chemistry and application to liquid-state DNP.
Ahmad IM +3 more
europepmc +1 more source
Oxidative Stress in Asthma Pathogenesis: Mechanistic Insights and Emerging Biomarker Signatures. [PDF]
Semyte JB, Kvedariene V.
europepmc +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Radicals in Action: A Festival of Radical Transformations [PDF]
openaire +5 more sources
ORAC: The Method of Choice for Determining Antioxidant Capacity of Food Products? [PDF]
Sadowska-Bartosz I, Bartosz G.
europepmc +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Spin-Correlated Luminescence of Mechanically Generated Radical Species. [PDF]
Yoshida S +3 more
europepmc +1 more source

