Results 251 to 260 of about 435,752 (317)

The therapeutic opportunities and pitfalls of using iron ion chelators to treat neurodegenerative diseases

FEBS Letters, EarlyView.
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley   +1 more source

Controlling distance, time and reactivity: Chemical principles of proximity labeling. [PDF]

Curr Opin Chem Biol
Ruenkam T, Wang Z, Juvekar V, Loh KH.
europepmc   +1 more source

Identification of the plant mitochondrial OrfX protein: A mass spectrometry approach

FEBS Letters, EarlyView.
The mitochondrial genome of plants contains an open reading frame, orfx, which encodes a rare protein that has so far escaped mass spectrometric detection. The protein resembles the c‐subunit of bacterial twin‐arginine‐motif‐dependent protein translocases (TatC).
Matthias Döring, Jan de Jonge, Hans‐Peter Braun, Nils Rugen   +3 more
wiley   +1 more source

Super-stable two-dimensional radical conjugated metal-organic frameworks for efficient NIR-II photothermal conversion. [PDF]

Sci Adv
Lyu S, Lu Y, Feng S, Zhang N, Chu Y, Yao Y, Sun C, He Y, Feng X, Wang Y.   +9 more
europepmc   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Acridine/Lewis acid photocatalysis enables α-amidyl radical cyclizations.

Org Chem Front
Joshi S, Rickertsen DRL, George EN, Ghiviriga I, Seidel D.   +4 more
europepmc   +1 more source

Synthesis of sterically shielded piperidine nitroxides via acid-catalyzed heterocyclization of β-aminoketone derivatives with ketones. [PDF]

Beilstein J Org Chem
Gulman MM, Glazachev YI, Dobrynin SA.
europepmc   +1 more source

Initiating radical polymerization at room temperature: Why and How? [PDF]

RSC Adv
Fu Y, Dai X, Lam KL, Das S, Zhang T.
europepmc   +1 more source

Kinetics-controlled radical coupling on dual redox-active sites for selective formamide production. [PDF]

Nat Commun
Shen S, Li J, Li X, Wang J, Zhang C, Dong F.   +5 more
europepmc   +1 more source

New Insights into Radical Mechanisms in Natural Drying Oils: Paint Binders as Reactors for Nanoparticle Formation. [PDF]

ACS Omega
de Viguerie L, Yang Y, Morlet-Savary F, Lalevée J, Casale S, Péchoux C, Jaber M, Patriarche G.   +7 more
europepmc   +1 more source