Results 51 to 60 of about 435,752 (317)

Exploring Short and Efficient Synthetic Routes Using Titanocene(III)-Catalyzed Reactions: Total Synthesis of Natural Meroterpenes with Trisubstituted Unsaturations

open access: yesMolecules, 2022
The stereo- and regioselective total syntheses of OMe derivatives of the scarce bioactive meroterpenoids makassaric acid (1) and fascioquinol B (2) have been accomplished.
Jennifer Rosales   +2 more
doaj   +1 more source

Insights into Mechanisms of Blood-Brain Barrier Permeability – Roles of Free Radicals, Matrix Metalloproteinsases, and Caveolin-1 [PDF]

open access: yes, 2014
Free radicals, including reactive oxygen species (ROS) and reactive nitrogen species (RNS), are important mediators in cerebral ischemia-reperfusion injury and other neurological diseases.
Shen, J, Jiangang Shen, Gu, Y, Yong Gu
core   +1 more source

Populations and Dynamics of Guanine Radicals in DNA strands—Direct versus Indirect Generation

open access: yesMolecules, 2019
Guanine radicals, known to be involved in the damage of the genetic code and aging, are studied by nanosecond transient absorption spectroscopy. They are generated in single, double and four-stranded structures (G-quadruplexes) by one and two-photon ...
Evangelos Balanikas   +3 more
doaj   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen   +23 more
wiley   +1 more source

Photoredox-catalyzed α-Scission vs β-Scission of PR3-OH Radicals: Synthetic Utilizations and Mechanistic Studies [PDF]

open access: yes, 2023
Photoinduced generation of phosphoranyl radicals offers a versatile strategy to access a variety of synthetically valuable radicals, which has opened exciting new opportunities for radical manipulations and synthetic chemistry.
Kai, Chen   +10 more
core   +1 more source

Health‐Related Social Needs in Children With Sickle Cell Disease Are Associated With Worse Health‐Related Quality of Life

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with sickle cell disease (SCD) face multiple acute and chronic medical complications that may impact their quality of life as reported by patients themselves. Health‐related social needs (HRSNs), such as food and housing insecurity, are common in people with SCD, but the association between HRSNs and patient‐reported ...
Sarah J. Marks   +5 more
wiley   +1 more source

Facile Synthesis of Spiro[cyclohexane-1,3’-indoline]-2,2’-diones

open access: yesHeterocyclic Communications, 2019
Spiro[cyclohexane-1,3’-indoline]-2,2’-diones were easily prepared in good to high yields by the oxidation of N-aryl-N-methyl-2-oxocyclohexane-1-carboxamides in one pot with a short reaction time.
Katayama Shin-taro, Nishino Hiroshi
doaj   +1 more source

Cup‐Like Nuclei Is a Hallmark of DUX4/ERG Acute Lymphoblastic Leukemia and Reveals Cytoplasmic Mitochondria Accumulation

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Cup‐like nuclei are a distinctive morphological feature observed in certain cases of acute lymphoblastic leukemia (ALL). We provide evidence that they characterize DUX4/ERG ALL independently of IKZF1 deletion and reveal marked mitochondrial accumulation in this ALL subset.
Chloé Arfeuille   +9 more
wiley   +1 more source

Recent Developments in the Reduction of Oxidative Stress through Antioxidant Polymeric Formulations

open access: yesPharmaceutics, 2019
Reactive oxygen and nitrogen species (RONS) are produced endogenously in our body, or introduced through external factors, such as pollution, cigarette smoke, and excessive sunlight exposure. In normal conditions, there is a physiological balance between
Muhammad Shajih Zafar   +3 more
doaj   +1 more source

Radical distinction: Support for radical left and radical right parties in Europe [PDF]

open access: yesEuropean Union Politics, 2017
Support for radical parties on both the left and right is on the rise, fueling intuition that both radicalisms have similar underpinnings. Indeed, existing studies show that radical left and right voters have overlapping positions and preferences. In this article, however, we focus on the differences in the voting bases of such parties.
Rooduijn, M.   +3 more
openaire   +4 more sources

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