Results 61 to 70 of about 15,758,065 (287)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Ultra-wideband optical diffractive network for mode multiplexing across the entire telecommunication range

Nature Communications
Advancements in multi-band and space division multiplexing (SDM) technologies are rapidly progressing to support growing data traffic. Current research focuses on hybrid multiplexing in the C + L bands, pushing SDM systems to achieve capacities exceeding
Aru Kong, Jianxin Ren, Kaihui Wang, Yongyi Yu, Rongyi Lin, Chen Wang, Jianyu Long, Fufei Pang, Xueli Chen, Xiaoyu Yan, Zhifeng Wang, Bo Liu, Ting Lei, Xiaocong Yuan   +13 more
doaj   +1 more source

Meta surface Assisted Open radio access networks

Wasit Journal of Engineering Sciences
The paradigm of the open radio access networks (O-RAN) seeks to carry intelligence and openness (multi-vendors) to the conventional proprietary and closed radio access networks (RAN) schemes and deliver performance enhancement, cost-efficiency, and ...
7haneenabdulrahman7 ajeel, Ismail Hburi
doaj   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Spectrum sharing models in cognitive radio networks [PDF]

, 2011
Spectrum scarcity demands thinking new ways to manage the distribution of radio frequency bands so that its use is more effective. The emerging technology that can enable this paradigm shift is the cognitive radio.
Rifà Pous, Helena, Rifà Coma, Josep
core  

Efficiency gains in 5G softwarised radio access networks

EURASIP Journal on Wireless Communications and Networking, 2019
This paper proposes the concept of compute resource disaggregation in centralized softwarised radio access networks. This approach allows individual allocation of processing functions to different servers depending on the nature and volume of their ...
Nikolaos Gkatzios, Markos Anastasopoulos, Anna Tzanakaki, Dimitra Simeonidou   +3 more
doaj   +1 more source

Radio Access for Future 5G Vehicular Networks [PDF]

2017 IEEE 86th Vehicular Technology Conference (VTC-Fall), 2017
Current wireless access technologies cannot satisfy all the requirements of future vehicular networks, and 5G could provide a solution to the actual limitations enabling super-fast, reliable, and low latency connections. The road to 5G vehicular networks can be considered opened by the Release 14 of Long Term Evolution (LTE), which enables vehicle-to ...
Barbara M. Masini, Alessandro Bazzi, Enrico Natalizio   +2 more
openaire   +6 more sources

A role for eIF5A in translational control of stress‐inducible proteins in multiple myeloma cell lines

Molecular Oncology, EarlyView.
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both, Ingrid A. M. Derks, Raphaël Vanleyssem, Marine Leclercq, Najla El Hachem, Pierre Close, Eric Eldering, Marco Vincent Haselager   +7 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source