Results 61 to 70 of about 3,665,886 (316)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

A W-Band 3-D Heterogeneously Integrated Radar Transmitter and Receiver

open access: yesIEEE Access
For W-band millimeter-wave radars, chip and packaging designs are often independent. The chip architecture may restrict packaging flexibility, forcing the adoption of high-loss wire bonding, and this independent design is prone to inter-chip near-field ...
Zhe Zhao   +7 more
doaj   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

Recent Applications of Focused Ion Beam–Scanning Electron Microscopy in Advanced Packaging

open access: yesJournal of Manufacturing and Materials Processing
Advanced packaging represents a crucial technological evolution aimed at overcoming limitations posed by Moore’s Law, driving the semiconductor industry from two-dimensional toward three-dimensional integrated structures.
Huan Zhang   +4 more
doaj   +1 more source

Arqueosemiótica: Entrevista al doctor Mannar Hammad. Charlas con Radio INAH

open access: yes, 2013
Para presentar al doctor Manar Hammad, nos parece importante mencionar los títulos de tres de sus libros, títulos inquietantes que nos permiten imaginar el alcance de sus interesantes líneas de investigación: "La privatización del espacio", "La ...
Radio INAH
core  

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

A Dual-Polarized Multi-Wideband Ceiling Antenna With Eight-Diagram Shape for 2G/3G/LTE/5G Sub-6 GHz Indoor Applications

open access: yesIEEE Access
This paper presents a dual-polarized, multi-wideband ceiling antenna with an eight-diagram shape for indoor communication in the 2G/3G/LTE/5G sub-6 GHz frequency range.
Botao Feng   +4 more
doaj   +1 more source

Arqueosemiótica: Entrevista al doctor Roberto Flores. Charlas con Radio INAH

open access: yes, 2014
El doctor Flores, lingüista de formación, se ha dedicado tanto al estudio del lenguaje, como a la historiografía, la publicidad y a los estudios literarios.
Radio INAH
core  

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

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