Results 91 to 100 of about 604,375 (292)

Forecasting foreground impact on cosmic microwave background measurements [PDF]

, 1998
We explore the possible impact of galactic and extragalactic foregrounds on measurements of the cosmic microwave background (CMB). We find that, given our present understanding of the foregrounds, they are unlikely to qualitatively affect the ability of ...
Aghanim, Atrio Barandela, Banday, Bersanelli, Bond, Bouchet, Bouchet, Bouchet, Brandt, de Oliveira Costa, de Oliveira Costa, Dodelson, Draine, Gautier, Gawiser, Gispert, Gorski, Guiderdoni, Hildebrand, Hobson, Hobson, Jones, Jungman, Kamionkowski, Kamionkowski, Keating, Knox, Kogut, Leitch, Lloyd Knox, McCullough, Prunet, Prunet, Refregier, Reynolds, Schlegel, Seljak, Seljak, Sethi, Tegmark, Tegmark, Tegmark, Toffolatti, White, Wright, Zaldarriaga, Zaldarriaga   +46 more
core   +2 more sources

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Effective Fingerprint Extraction and Positioning Method Based on Crowdsourcing

IEEE Access, 2019
At present, WiFi fingerprinting indoor positioning technology is a research hotspot, and the construction of a radio map based on crowdsourcing can significantly reduce the amount of labor required.
Ning Yu, Shengnan Zhao, Xiaofeng Ma, Yinfeng Wu, Renjian Feng   +4 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Adaptive Density Graph-Based Manifold Alignment for Fingerprinting Indoor Localization

IEEE Access, 2020
The received signal strength (RSS) fingerprint-based indoor localization has been considered as a promising solution, due to its relatively high localization accuracy and its ease of use in widespread Wireless Local Area Network (WLAN) infrastructure.
Shibao Li, Qingshuai Zhao, He Li, Shengzhi Wang, Tingpei Huang, Jianhang Liu   +5 more
doaj   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

Optimizing radio map for WLAN fingerprinting

2010 Ubiquitous Positioning Indoor Navigation and Location Based Service, 2010
In this paper, questions related to design of WLAN radio map for fingerprinting based positioning were investigated. The experiment results show that with histogram based algorithms, the positioning accuracy improves as the number of histogram bins increases until the number of bins reaches eight. With the number of bins lower than this, the uneven bin
Leppäkoski, Helena, Tikkinen, Saija, Takala, Jarmo   +2 more
openaire   +2 more sources

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

EKF–GPR-Based Fingerprint Renovation for Subset-Based Indoor Localization with Adjusted Cosine Similarity

Sensors, 2018
Received Signal Strength Indicator (RSSI) localization using fingerprint has become a prevailing approach for indoor localization. However, the fingerprint-collecting work is repetitive and time-consuming.
Junhua Yang, Yong Li, Wei Cheng, Yang Liu, Chenxi Liu   +4 more
doaj   +1 more source

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source