Results 111 to 120 of about 1,091,526 (300)

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Long-term Simultaneous 2.25/8.60 GHz Monitoring of the Newly Discovered Repeating FRB 20240114A

The Astrophysical Journal
We report on the simultaneous monitoring of the repeating fast radio burst (FRB) 20240114A at 2.25 and 8.60 GHz, conducted 66 times between 2024 January 29 and 2025 February 15 with the Shanghai Tianma Radio Telescope.
Xiao-Wei Wang, Zhen Yan, Zhi-Qiang Shen, Ke-Jia Lee, Ya-Jun Wu, Rong-Bing Zhao, Jie Liu, Rui Wang, Kuo Liu, Yuan-Chuan Zou, Zhi-Peng Huang, Chu-Yuan Zhang, Fan Yang, Zhen-Long Liao, Yang-Yang Lin   +14 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Physics of Nonthermal Radio Sources [PDF]

, 1964
On December 3 and 4, 1962, the Goddard Institute for Space Studies, an office of the National Aeronautics and Space Administration, was host to an international group of astronomers and physicists who met to discuss the physics of nonthermal radio ...
Cameron, A. G. W., Maran, Stephen P.
core   +1 more source

A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento, Daniela F. Santos, Tuane C. R. G. Vieira, Tiago F. Outeiro   +3 more
wiley   +1 more source

Screening Routine Clinical Notes for Epilepsy Surgery Candidates Using Large Language Models

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy surgery is severely underutilized despite proven efficacy, with substantial under‐referral of eligible patients in routine clinical practice. This study evaluated the potential role of large language models (LLMs) as decision‐support tools for screening unstructured clinical notes to identify epilepsy surgery candidates and ...
Uriel Fennig, Nadav Amir, Maya Schiller, Roni Loebenstein, Johnatan Nissan, Marina Boxer, Shany Guly Gofrit, Gal Goshen, Sándor Beniczky, Nicola Maggio   +9 more
wiley   +1 more source

Narrowly Banded Spectra with Peak Frequency around 1 GHz of FRB 20201124A: Implications for Energy Function and Radiation Physics

The Astrophysical Journal
The radiation physics of fast radio bursts (FRBs) remains an open question. Current observations have discovered that narrowly banded bursts of FRB 20201124A are active in 0.4–2 GHz, and their spectral peak frequency ( ${\nu }_{p}^{\mathrm{obs}}$ ) is ...
Fen Lyu, En-Wei Liang, D. Li
doaj   +1 more source

CENSORS: A Combined EIS-NVSS Survey Of Radio Sources. I. Sample definition, radio data and optical identifications

, 2003
A new sample of radio sources, with the designated name CENSORS (A Combined EIS-NVSS Survey Of Radio Sources), has been defined by combining the NRAO VLA Sky Survey (NVSS) at 1.4 GHz with the ESO Imaging Survey (EIS) Patch D, a 3 by 2 degree region of ...
Allington-Smith, Baars, Benoist, Bertin, Best, Best, Best, Best, Blake, Bremer, Chambers, Condon, Condon, Daddi, de Ruiter, Dunlop, Dunlop, Dunlop, Eales, Eales, Eales, Eales, Fanaroff, Finn, Gavazzi, Greisen, H. J. A. Röttgering, Inskip, Inskip, J. N. Arts, J. Wall, Jarvis, Lacy, Laing, Lara, Lilly, M. H. Brookes, Machalski, McCarthy, McCarthy, McCarthy, Mobasher, Neeser, Nonino, Oort, Overzier, P. N. Best, Peacock, Poggianti, Pooley, Porciani, Prestage, R. Rengelink, Rawlings, Rengelink, Richards, Richstone, Richter, Sadler, Snellen, Snellen, Soneira, Soneira, Spinrad, Waddington, Wall, Wall, Willott, Willott, Willott, Willott, Wold, Woo   +72 more
core   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit, Chiranth K. Nagaraj, Jackson S. Newell, Kim Truc Nguyen, Xilal Y. Rima, Jacob Doon‐Ralls, Eduardo Reátegui, Jeffrey M. Statland, Rabi Tawil, Kevin M. Flanigan, Scott Q. Harper, Nizar Y. Saad   +11 more
wiley   +1 more source

Statistical and Temporal Analysis of Multicomponent Burst Clusters from the Repeating FRB 20190520B

The Astrophysical Journal
Fast radio bursts (FRBs) are bright, millisecond-duration extragalactic radio transients that probe extreme astrophysical environments. Many FRBs exhibit multicomponent structures, which encode information about their emission mechanisms or progenitor ...
Jia-heng Zhang, Chen-Hui Niu, Yu-hao Zhu, Di Li, Yu Wang, Wei-yang Wang, Yi Feng, Xin-ming Li, Jia-rui Niu, Pei Wang, Yun-wei Yu, Yong-kun Zhang, Xiao-ping Zheng   +12 more
doaj   +1 more source