Results 41 to 50 of about 163,561 (298)

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Multiwavelength Observations of the Apparently Nonrepeating FRB 20250316A

open access: yesThe Astrophysical Journal
The physical origin of fast radio bursts (FRBs) remains uncertain. Although multiwavelength observations have been widely conducted, only Galactic FRB 20200428D is associated with an X-ray burst from the magnetar SGR J1935+2154.
Ye Li   +74 more
doaj   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Simultaneous Multiwavelength Observations of the Repeating Fast Radio Burst FRB 20190520B with Swift and FAST

open access: yesThe Astrophysical Journal
Among several dozen known repeating fast radio bursts, those precisely localized offer the best opportunities to explore their multiwavelength counterparts, which are key to uncovering their origins.
Zhen Yan   +10 more
doaj   +1 more source

DISCOVERY OF A METER-WAVELENGTH RADIO TRANSIENT IN THE SWIRE DEEP FIELD: 1046+59 [PDF]

open access: yes, 2012
We report the results of a low frequency radio variability and slow transient search using archival observations from the Very Long Array. We selected six 325 MHz radio observations from the spring of 2006, each centered on the Spitzer-Space-Telescope ...
T. R. Jaeger   +4 more
semanticscholar   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Low-frequency, Wideband Study of an Active Repeater, FRB 20240114A, with the GMRT

open access: yesThe Astrophysical Journal
We report the detection of 167 bursts from an active repeater, FRB 20240114A, using the upgraded Giant Metrewave Radio Telescope. The observations were carried out over a frequency range of 300–750 MHz, and on four different dates over a period of 6 ...
U. Panda   +4 more
doaj   +1 more source

Transcriptional regulation of neuropeptide receptors underlies context‐dependent adaptation in Drosophila melanogaster

open access: yesFEBS Open Bio, EarlyView.
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu   +6 more
wiley   +1 more source

Polarization Characteristics of the Hyperactive FRB 20240114A

open access: yesThe Astrophysical Journal Supplement Series
Fast radio bursts (FRBs) are transient radio bursts of extragalactic origin characterized by millisecond durations and high luminosities. We report on observations of FRB 20240114A conducted with the Robert C.
Jin-Tao Xie   +16 more
doaj   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

open access: yesFEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

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