Results 171 to 180 of about 1,886,057 (217)

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, Volume 16, Issue 9, Page 1825-1839, September 2026.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

Pulmonary ventilation images from planning CT images using deep learning on locally‐advanced NSCLC patients

open access: yesJournal of Applied Clinical Medical Physics, Volume 27, Issue 9, September 2026.
Abstract Background Pulmonary ventilation imaging has become an increasingly important component in thoracic radiotherapy, as it is applied to functional avoidance radiotherapy, where radiation doses are strategically minimized to preserve functional lung regions.
Yoshiyuki Katsuta   +8 more
wiley   +1 more source

CCL3 and IL‐7 Synergistically Enhance CAR‐T Efficacy in Solid Tumors

open access: yesAdvanced Science, Volume 13, Issue 49, 3 September 2026.
Synergistic delivery of CCL3 and IL‐7 by CAR‐T cells overcomes the immunosuppressive tumor microenvironment by enhancing cell infiltration, survival, and local immune reprogramming. This also establishes positive feedback that amplifies anti‐tumor activity and memory responses in both CAR‐T and endogenous T cells, presenting a robust therapeutic ...
Huanpeng Chen   +12 more
wiley   +1 more source

The battleship study: An innovation towards precision in prostate biopsy and brachytherapy grid usage

open access: yesBJUI Compass, Volume 7, Issue 9, September 2026.
Abstract Objectives This study aimed to compare the efficiency and accuracy of a conventional prostate brachytherapy grid with a novel Zebra grid using a laboratory‐based simulation model (ProGrid model). Methods This prospective and comparative experimental pilot study was conducted using a nonclinical brachytherapy simulation model (ProGrid Model ...
Vishen Naidoo   +3 more
wiley   +1 more source

Corruption Control and Corporate Hazardous Waste Emissions: Cross‐Country Evidence and the Moderating Role of Agenda 2030

open access: yesBusiness Strategy and the Environment, Volume 35, Issue 6, Page 8946-8971, September 2026.
ABSTRACT The aim of this study is to examine the impact of corruption control, as a public institutional mechanism, on hazardous waste emissions of private sector entities. We also examine the extent to which Agenda 2030 moderates the relationship. We analyse data from the top 500 global companies.
Babajide Oyewo   +3 more
wiley   +1 more source

Metal Ions in Longgu (Fossilized Bone) as a Natural Synergistic Network for Multi‐Target Therapy in Psychiatric Disorders

open access: yesChemistry &Biodiversity, Volume 23, Issue 9, September 2026.
Longgu (fossilized bone) delivers a natural synergistic network of metal ions, Ca2+, Mg2+, Zn2+, Fe, Cu, and Mn2+ that collectively targets the interconnected pathologies of anxiety, depression, and insomnia. This multi‐ion system operates through coordinated mechanisms including ionostatic balance, cross‐pathway synergy, and systemic integration ...
Sun Xiujia   +7 more
wiley   +1 more source

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