Results 181 to 190 of about 1,886,057 (217)

Polycythemia Vera and Essential Thrombocythemia: A Nationwide Population-Based Study on Treatment Patterns, Vascular Complications and Survival. [PDF]

Eur J Haematol
Larsson AE, Renlund H, Andréasson B, Holmberg H, Liljeholm M, Själander A.   +5 more
europepmc   +1 more source

Efficacy and Safety of Initial Low‐Dose, Extended‐Interval Nivolumab Monotherapy in a 91‐Year‐Old Patient With Locally Advanced NSCLC and Poor Performance Status: A Case Report

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT The incidence of non‐small cell lung cancer (NSCLC) increases with age, with approximately half of the cases diagnosed in individuals aged 70 and older. In numerous clinical trials, immune checkpoint inhibitors (ICIs) have demonstrated significant efficacy in treating NSCLC without driver gene mutations.
Dan Kou, Xiang Yan, Qi Huang, Jingye Zhong, Qiongcheng Chen, Tao Zhao, Xianhua Xu   +6 more
wiley   +1 more source

Advancing Aquatic Ecotoxicology Testing of Anticancer Drugs Through Mesocosms. [PDF]

Molecules
Carboni A, Calvaresi M.
europepmc   +1 more source

Primary Mammary Angiosarcoma in a Postmenopausal Woman: A Case Report

Cancer Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background Primary breast angiosarcoma (PAS) is a rare aggressive mesenchymal breast tumor, which predominantly affects young premenopausal women and is prone to misdiagnosis due to nonspecific clinical and imaging features. Surgical resection is the main treatment, while the efficacy of adjuvant chemoradiotherapy remains unclear.
Tingting Liu, Yueqin Xu, Qingwei Wang, Shiya Yu, Hongming Lin, Zeyi Ye, Zhiqiang Zheng, Changan Yang, Tianzi Hong   +8 more
wiley   +1 more source

Dual Role of AITD in TgAb-Positive PTC: Delayed Antibody Clearance with Enhanced RAIT Response. [PDF]

Cancer Manag Res
Ge H, Chen S, Song L, Lin Z, Li Y, Chen W.   +5 more
europepmc   +1 more source

Payload‐Based Clinical Pharmacology Review of Approved Antibody–Drug Conjugates: Commonalities and Considerations for Streamlined Development

Clinical Pharmacology &Therapeutics, Volume 120, Issue 3, Page 614-638, September 2026.
Antibody–drug conjugates (ADCs) combine the specificity of an antibody with the potency of a cytotoxic drug. Thirteen ADCs, utilizing seven unique cytotoxic payloads and targeting 11 distinct antigens, are currently approved by the US Food and Drug Administration as of June 2025, representing a rapidly growing and highly promising class of anticancer ...
Sijie Lu, Qingqing Xiao, Lixuan Qian, Siyuan Sun, Zhu Zhou, Michael Z. Liao, Chunze Li   +6 more
wiley   +1 more source

Metabolism Pathway Blood Proteomic Differences in Lewy Body Dementia Compared to Alzheimer's Disease. [PDF]

Int J Mol Sci
Pritha AN, Chouliaras L, Swann P, Prats-Sedano M, McKeever A, Heslegrave A, Ashton NJ, Zetterberg H, Su L, Malpetti M, Rowe JB, O'Brien JT.   +11 more
europepmc   +1 more source

Cancer cell‐selective ectopic expression of CD20 as an antigen enables rituximab repurposing for solid tumour immunotherapy

Clinical and Translational Medicine, Volume 16, Issue 9, September 2026.
A recombinant AAV delivered tumour gene therapy. NF‐κB drives tumour‐selective antigen (e.g., CD20) expression. Ectopic CD20 enables rituximab repurposing to solid tumours. ADCC, ADCP, and CDC contribute to the antitumour activity. Abstract Background Despite the clinical success of cancer immunotherapies, their efficacy is often compromised by antigen‐
Ziyan Kong, Yile Wang, Yunqi Zhao, Lu Wang, Zhimin Fan, Yongqian Shu, Jinke Wang   +6 more
wiley   +1 more source

Radiological and chemical hazards of persistent organic pollutants in the textile sector. [PDF]

Sci Rep
Fouda SH, El-Halim ESA, Ghany HAA.
europepmc   +1 more source

Migration and Accumulation of Uranium-Associated Heavy Metals in Mining-Affected Ecosystems (Water, Soil, and Plants). [PDF]

Biology (Basel)
Kairullova M, Bakhtin M, Ilbekova K, Ibrayeva D.   +3 more
europepmc   +1 more source