Results 31 to 40 of about 3,582,501 (299)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Dactolisib outperforms Rapamycin in potentiating apoptosis induced by XPO1, Bcl‐2 and Mcl‐1 blockade in preclinical glioblastoma models

FEBS Open Bio, EarlyView.
The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao, Leonie Meyer, Madita Braun, Katharina Otte, Celine Bitter, Maite Pawlik, Hartmann Raifer, Frederik Helmprobst, Axel Pagenstecher, Hans Urban, Michael C. Burger, Michael W. Ronellenfitsch, Joachim P. Steinbach, Jarmila Jedelská, Shamim Bagheri, Behrooz H. Yousefi, Pietro Di Fazio, Markus Luster, Andreas H. Mahnken, Andreas Neubauer, Andreas Burchert, Christopher Nimsky, Jörg W. Bartsch, Tillmann Rusch   +23 more
wiley   +1 more source

Density Measurement of Irradiated and Nonirradiated Zirconium Oxide by Ptychographic X‐Ray Computed Tomography (PXCT)

Advanced Engineering Materials, EarlyView.
Mass density governs the protective behavior of oxide layers on nuclear fuel cladding. Ptychographic X‐ray computed tomography measures zirconium oxide grown on Zircaloy‐4 under reactor and autoclave conditions, revealing nearly identical bulk densities of 5.1 ± 0.80 g cm−3.
Okan Yetik, Liliana I. Duarte, Malgorzata G. Makowska, Roland Brütsch, Andrej Bullemer, Ana Diaz, Mirko Holler, Andreas Menzel, Johannes Bertsch, Pavel Trtik   +9 more
wiley   +1 more source

The Preparation Method of 22Na Gamma Radiation Source

Journal of Isotopes
Gamma-ray densitometers are widely used in industry due to their insensitivity to the measured medium and convenient installation. The gamma-ray radioactive source is the core component of the gamma-ray densitometer.
Mingyang LIU, Chunxia REN, Yan GAO
doaj   +1 more source

Radiation doses assessment for workers on radiation measuring devices response check in RNSD laboratories

Iraqi Journal of Physics, 2019
Radiation measuring devices need to periodic calibration process to examine their sensitivity and the extent of the response. This study is used to evaluate the radiation doses of the workers in the laboratories of the Directorate of Safety as a result ...
Abbas N. Mohammed
doaj   +1 more source

Implementation of safety and security standards for high dose rate brachytherapy sealed radioactive source used in a medical radiation facility

Radiation Medicine and Protection, 2020
Objective: To provide guidance on basic concepts and elements for radiation safety and security measures for a HDR brachytherapy sealed radioactive source in a medical radiation facility.
Rajni Verma, Gourav Kumar Jain, Arun Chougule   +2 more
doaj   +1 more source

Insinuation Salmonella Typhi for 23Na and 60Co Radioactive Sources

Al-Mustansiriyah Journal of Science, 2023
The study investigates the effect of radioactive sources on Salmonella typhi, a gram-negative, rod-shaped bacterium that infects various cell types. Salmonella primarily spreads through contaminated food, commonly tainted by human or animal waste.
Hanaa Salih Sabaa, Nebras Rada Mohammed, Hayim Chasib Magid, Ali Abdulwahab Ridha, Waleed Jabar Mhana, Saad N. Ibrahim   +5 more
doaj   +1 more source

Performance Assessment Transport Modeling of Uranium at the Area 5 Radioactive Waste Management Site at the Nevada National Security Site [PDF]

, 2010
Following is a brief summary of the assumptions that are pertinent to the radioactive isotope transport in the GoldSim Performance Assessment model of the Area 5 Radioactive Waste Management Site, with special emphasis on the water-phase reactive ...
null NSTec Radioactive Waste, Waste, NSTec Radioactive   +1 more
core   +1 more source

Nitride MXenes Beyond Carbides: Bridging the Gap Between Computational Prediction and Experimental Realization

Advanced Functional Materials, EarlyView.
Nitride MXenes remain constrained by a persistent gap between computational prediction and experimental realization. This Review identifies the thermodynamic, kinetic, and chemical barriers limiting their synthesis, critically evaluates emerging fabrication routes, and proposes a multidimensional computational‐experimental framework to accelerate the ...
Naresh Varnakavi, Masoud Soroush
wiley   +1 more source

USE UNDERGROUND MINES FOR DISPOSAL OF RADIOACTIVE WASTE OF THE 3RD AND 4TH CLASSES

Известия Томского политехнического университета: Инжиниринг георесурсов, 2023
Link for citation: Gorin N.V., Kuchinov V.P., Usanov S.V., Vasiliev A.P. Use of underground mines for disposal of radioactive waste of the 3rd and 4th classes. Bulletin of the Tomsk Polytechnic University. Geo Аssets Engineering, 2023, vol. 334, no.
Nikolay V. Gorin, Vladimir P. Kuchinov, Sergey V. Usanov, Albert P. Vasiliev   +3 more
doaj   +1 more source