Results 111 to 120 of about 398,650 (328)
From Design to Outcome: The Role of Bi‐ and Multifunctional Ligands in Modern Therapeutics
This review highlights the innovative use of bi‐ and multifunctional ligands for precision therapeutics. From strategic linker design to bioorthogonal conjugation and nanoscaffold integration, these approaches enable precise targeting, high‐resolution receptor mapping, and enhanced drug delivery.
Célia Bouacha+2 more
wiley +1 more source
Role of SLC16A10 in Psoriasis Through the Regulation of Arachidonic Acid Metabolism in Keratinocytes
This study demonstrates that SLC16A10 plays a crucial role in psoriasis pathogenesis through arachidonic acid metabolism regulation in keratinocytes. Using multi‐omics analysis and experimental validation, researchers identify SLC16A10 as both a diagnostic biomarker and therapeutic target.
Jingyuan Yang+17 more
wiley +1 more source
Growth Responses of Holcus lanatus L. (Velvet Grass) in Soils Contaminated with Cesium or Strontium
Radiocesium (r-Cs) and radiostrontium (r-Sr) released from nuclear accidents (e.g., Chornobyl, Fukushima) and routine operations (reactors, reprocessing) pose environmental and health concerns.
Bayezid M. Khan+3 more
doaj +1 more source
Natural and artificial radioactivity appears to be different in different geological regions. Moreover, the radionuclides may migrate to the deeper region of the earth after deposition, and the depth profile of a radionuclide reveals information on the ...
Sheikh Shariful Islam+9 more
doaj +1 more source
THE SPECIFIC RADIOACTIVITY OF URANIUM.1 [PDF]
Herbert N. McCoy, William H. Ross
openalex +1 more source
Long Term High‐Salt Diet Induces Cognitive Impairments via Down‐Regulating SHANK1
The study identifies a novel mechanistic link between long‐term HS diet and cognitive impairment, wherein PKA/CREB axis inactivation leads to SHANK1 reduction, synaptic damage, and cognitive deficits. Abstract High‐salt (HS) diet is an established risk factor for cognitive impairment, but the underlying mechanisms remain unclear.
Cuiping Guo+10 more
wiley +1 more source
The study reveals that PAXIP1‐associated glutamate‐rich protein 1 (PAGR1), a glucose‐responsive regulator in skeletal muscle, modulates systemic glucose homeostasis and hepatic metabolism. Muscle‐specific PAGR1 deletion enhances insulin signaling, promotes glucose transporter 4 (GLUT4) translocation, and protects against high‐fat‐diet‐induced insulin ...
Chenyun Ding+19 more
wiley +1 more source
Modelling of radiocesium transfer in the lichen-reindeer/caribou-wolf food chain
The environmental contaminate radiocesium (cesium-137) has been shown to be of value as a marker in food selection and intake studies. Its greatest potential value as a food marker is in the subarctic/arctic regions, particularly in the lichen to ...
D. F. Holleman+2 more
doaj +1 more source
Determination of the radioactivity of the Quincy [Massachusetts] granite by the photographic method [PDF]
Aaron Co Hee+2 more
openalex +1 more source