Results 131 to 140 of about 257,139 (292)

Natural radioactivity and associated hazard indices from a gas field (Fenchuganj, Bangladesh): Assessment and management guidelines. [PDF]

PLoS One
Begum M, Hossain S, Rashid MB, Habib MA, Khan R, Siraz MMM, Yeasmin S, Al Mamun SMM, Hossain SM.   +8 more
europepmc   +1 more source

Progress report on new epilepsy treatments: A summary of the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XVIII). II. Treatments in more advanced clinical development

Epilepsia, EarlyView.
Abstract This article summarizes data for 13 investigational treatments for which at least preliminary seizure outcome data in patients with epilepsy were reported at the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices held in Madrid, Spain, on May 3–6, 2026.
Meir Bialer, Cecilie Johannessen Landmark, Matthias J. Koepp, Emilio Perucca, Piero Perucca, Torbjörn Tomson, H. Steve White, Elaine Wirrell   +7 more
wiley   +1 more source

Mass balance, excretion, and pharmacokinetics of a single oral dose of [¹⁴C]pixavir marboxil in healthy Chinese male participants. [PDF]

Front Pharmacol
Zhao C, Yang Y, Liu G, Qian L, Liu Y, Tsai CY, Chang LW, Chen Q, Qian H, Jia J, Liu Y.   +10 more
europepmc   +1 more source

Progress report on new epilepsy treatments: A summary of the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XVIII). I. Treatments in preclinical and early clinical development

Epilepsia, EarlyView.
Abstract Over the last 34 years, the Eilat Conference on New Antiepileptic Drugs and Devices has provided an interactive forum for stakeholders to discuss investigational and recently licensed treatments for seizures and epilepsy. The Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XVIII) took place in Madrid, Spain, on May 3 ...
Meir Bialer, Cecilie Johannessen Landmark, Matthias J. Koepp, Emilio Perucca, Piero Perucca, Torbjörn Tomson, H. Steve White, Elaine Wirrell   +7 more
wiley   +1 more source

Absorption, distribution, metabolism, and excretion of [¹⁴C]SH-1028, a third-generation <i>EGFR</i>-TKI, in rats and humans. [PDF]

Front Pharmacol
Zhou S, Wu Y, Liu W, Zhou C, Xie L, Zhuang Q, Wang L, Chen J, Zhu B, Zhang C, Zhang X, Shao F.   +11 more
europepmc   +1 more source

Epilepsy surgery: From bench to the clinics

Epilepsia Open, EarlyView.
Abstract Objective Recent advances in epilepsy surgery in patients with intractable epilepsy make it possible to study the mechanism of epilepsy in human brains. However, the true extent and propagation of each epileptogenic area from the epileptogenic focus in each patient is still difficult to perform “epilepsy cure” by surgery.
Tatsuya Tanaka
wiley   +1 more source

Pharmacokinetics, mass balance, and metabolism of [¹⁴C]SPH3127 (sitokiren), a novel direct renin inhibitor in humans. [PDF]

Front Pharmacol
Ma S, Huang X, Yan S, Liu H, Zhang H, Zhang Y, Cui W, Ding C, Diao X, Miao L.   +9 more
europepmc   +1 more source

Clinical Impact of Target‐Mediated Drug Disposition of Small Molecules with Focus on Early Phase I Study Designs

Clinical Pharmacology &Therapeutics, EarlyView.
Francesca Tessaro, Neil John Parrott, Matthias B Wittwer, Franziska Schaedeli Stark, Andrés Olivares‐Morales, Michael Derks, Stefan Sturm   +6 more
wiley   +1 more source

Neurometabolite abnormalities and associations with epilepsy duration and cognition in patients with idiopathic generalized epilepsies

Epilepsia Open, EarlyView.
Abstract Objective This study investigated whether idiopathic generalized epilepsies (IGEs) are associated with neuroinflammation by measuring neurometabolite levels and brain temperature using whole‐brain magnetic resonance spectroscopy imaging (MRSI).
Yun Lien, Christina Bankston, Ayushe A. Sharma, Brandon S. Mitchell, Rodolphe Nenert, Anna Moyana, Jennifer Pilkington, Roy C. Martin, Charity J. Morgan, Lawrence Ver Hoef, Jerzy P. Szaflarski, Jane B. Allendorfer   +11 more
wiley   +1 more source

Lymphatic Drainage of Cerebrospinal Fluid Using Lymph Node Seeker 64Cu-Labeled Gram-Negative Bacterial Extracellular Vesicles With Positron Emission Tomography (PET). [PDF]

J Extracell Vesicles
Kim K, Lee C, Shin H, Yoo RJ, Choi Y, Lee C, Kim I, Lee J, Suh M, Lee YS, Gho YS, Lee DS.   +11 more
europepmc   +1 more source