Results 141 to 150 of about 383,199 (293)

Absolute Bioavailability and Absorption, Distribution, Metabolism, and Excretion of [¹⁴C]Xevinapant, a Potent, Oral, Small-Molecule IAP Inhibitor. [PDF]

Clin Pharmacol Drug Dev
Menetrey A, Nicolas-Metral V, Roubaudi-Fraschini MC, Tat T, Zhao Y, Vugmeyster Y, Venkatakrishnan K, Rohdich F, Scheible H.   +8 more
europepmc   +1 more source

Application of Ultrasonic Sensors for Determining the Height of Dynamic Two‐Phase Layers in Tray Columns

Chemie Ingenieur Technik, EarlyView.
Ultrasonic sensors are evaluated for their applicability in dynamic gas–liquid systems. By comparing sensor data with two independent optical reference methods, their robustness and reliability are demonstrated under varying flow conditions and tray geometries in column systems.
Niklas Breuer, Marcus Grünewald, Julia Riese   +2 more
wiley   +1 more source

Toxicokinetic and Partial Mass Balance Assessment of ¹⁴C-Alpha Olefins in Rats. [PDF]

J Xenobiot
Shi Q, Dunn J, Carrillo JC, Penman MG, Powrie RH, Haines C, Shen H, Tian Y, Jia S, Hubert F, Boogaard PJ.   +10 more
europepmc   +1 more source

Spatially resolved 23Na magnetic resonance dispersion measurement in porous media

The Canadian Journal of Chemical Engineering, EarlyView.
Quantitative 23Na MRI was employed to analyze dispersion in realistic core plug samples and was compared with the conventional breakthrough curve. 23Na MRI provided a more effective aassessment of core plug heterogeneity than the conventional method. Abstract Tracer tests are widely used in the petroleum industry to assess reservoir core plugs, relying
Rheya Rajeev, Mohammad Sadegh Zamiri, Andrés Ramírez Aguilera, Florea Marica, Laura Romero de Zerón, Bruce J. Balcom   +5 more
wiley   +1 more source

Inductively coupled plasma mass spectrometry as a sensitive non-radioactive alternative for quantitative analysis in drug metabolism studies based on fluorine detection. [PDF]

Anal Bioanal Chem
Wouters S, Cuyckens F.
europepmc   +1 more source

Worldwide isotope ratios of the Fukushima release and early-phase external dose reconstruction [PDF]

, 2013
Bossew, P., Chaisan, K., Kirchner, G., Laptev, G., Smith, Jim   +4 more
core   +1 more source

Isoform Specificity of a Compound Targeting Actin Filaments Containing Tropomyosin Tpm1.8/1.9

Cytoskeleton, EarlyView.
ABSTRACT The unbranched actin filaments in mammalian cells are usually composed of co‐polymers of a specific tropomyosin isoform with actin. Genetic manipulation has revealed that the tropomyosins largely define the functional properties of actin filaments in an isoform‐specific, non‐redundant manner.
Jeff Hook, Edna C. Hardeman, Peter W. Gunning   +2 more
wiley   +1 more source

Contrast-enhanced T₁-weighted MRI, ¹¹C-DPA-713 PET and ¹¹C-CPPC PET as predictive imaging biomarkers of neuroinflammation in radiotherapy-induced brain injury. [PDF]

Sci Rep
Maiti S, Yadav SK, Teitz M, Velarde E, Lee S, Lecksell K, Bibic A, Ngen EJ.   +7 more
europepmc   +1 more source

Advances in Human Mass Balance Studies: An IQ Consortium Perspective on Current Practices and Emerging Trends

Clinical Pharmacology &Therapeutics, EarlyView.
Human radiolabeled mass balance studies are crucial for comprehensively characterizing the absorption, distribution, metabolism, and excretion (ADME) of investigational drugs, providing essential data for drug development, regulatory evaluation, and product labeling.
Jason Boer, Ellen Cannady, Filip Cuyckens, Ulrike Glaenzel, Camille Granvil, Felix Huth, Alexander D. James, Wenying Li, Céline Veau, Graeme Young, Qin Yue, Gregory S. Walker, Upendra A. Argikar, Jonathan N. Bauman, Cathy Cantalloube, Yu‐Luan Chen, Ping Kang, Patricia Moliner, Mette L. Pedersen, Isabel Piel, Simone Schadt, Hanno Schieferstein, Julia Suchomel, Shuai Wang, S. Cyrus Khojasteh   +24 more
wiley   +1 more source

A Human Mass Balance and Metabolism Study of [¹⁴C]-Ubrogepant in Healthy Male Adults. [PDF]

Clin Pharmacol Drug Dev
Boinpally RR, Rowe J, Chandrasekar P, White RB, Marcantonio EE, Trainor N, Liang Y, Maciolek C, Small JH, Houle R, Hafey MJ, Xie H, Yabut J, Fandozzi C.   +13 more
europepmc   +1 more source