Results 151 to 160 of about 383,199 (293)

Analysis and Characterization of Kisspeptin and Its Analogues in Serum and Urine Samples by Liquid Chromatography–High‐Resolution Mass Spectrometry for Doping Control Purposes

open access: yesDrug Testing and Analysis, EarlyView.
Sensitive LC‐HRMS methods were established for the detection of kisspeptin and its analogues in serum and urine, alongside their analytical and metabolic characterization. Stability studies were conducted in serum, plasma, and urine, highlighting the importance of appropriate sample handling for reliable anti‐doping analysis.
Sophia Krombholz   +3 more
wiley   +1 more source

Permeability of granite from a shallow buried mountain pipe gallery tunnel under unloading confining pressure

open access: yesDeep Underground Science and Engineering, EarlyView.
Triaxial compression tests under unloading confining pressure conditions were conducted to systematically analyze the permeability behavior of granite retrieved from the different classification surrounding rocks. Abstract The rock mass within mountain tunnels undergoes complex changes in permeability, strength, and deformation during tunneling ...
Xiaoyan Zhang   +4 more
wiley   +1 more source

The damage and failure mechanism of prestatically loaded rock during medium‐strain rate cyclic impact loading

open access: yesDeep Underground Science and Engineering, EarlyView.
Based on experimental results and theoretical analysis, an established rock damage accumulation model that comprehensively considers the preapplied static load, impact peak value, impact frequency, and impact times. Abstract To study the rock damage mechanism under high static loading and superimposed medium strain rate cyclic impact loading, a series ...
Wei Wang   +6 more
wiley   +1 more source

A rock brittleness index based on the postpeak energy release rate and damage surface characteristics for brittle hard rock

open access: yesDeep Underground Science and Engineering, EarlyView.
This study examines energy evolution in rock rupture via triaxial direct shear tests, exploring the impact of confining pressure and temperature on fracture surface randomness. A novel energy‐based brittleness index is proposed, validated experimentally, and compared with existing methods for reliability and accuracy.
Biao Wang   +5 more
wiley   +1 more source

Guided Sample Pooling in Human Mass Balance Studies: A Recommended Strategic Decision Framework. [PDF]

open access: yesClin Pharmacol Ther
Cuyckens F   +21 more
europepmc   +1 more source

Thermal‐induced fracture evolution and acoustic signature of Beishan granite: Insights into tensile strength of barrier system for high‐level radioactive waste disposal

open access: yesDeep Underground Science and Engineering, EarlyView.
The tensile strength of granite, a proposed host for nuclear waste, degrades severely above 400°C. We link this to specific microcracking patterns captured by acoustic emission, establishing a scientific basis for assessing repository safety under thermal load.
Wei Zeng   +7 more
wiley   +1 more source

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