Results 221 to 230 of about 380,351 (277)

Automated quality assurance of HDR brachytherapy: Evaluation of Dwell‐position accuracy and Dwell‐time linearity via image processing of radiochromic films

open access: yesPrecision Radiation Oncology, EarlyView.
This study develops a method combining radiochromic film and image processing to assess HDR brachytherapy source accuracy and linearity, achieving high precision and efficiency . Abstract Purpose To develop and validate a fully automated quality assurance method for high‐dose rate (HDR) brachytherapy, enabling the precise evaluation of source dwell ...
Qingqing Yuan   +4 more
wiley   +1 more source

A Pilot Study of 18F‐rhPSMA‐7.3‐PET/MRI to Reduce Mischaracterization of Active Surveillance and Focal Therapy Candidates With Occult Higher Risk Disease

open access: yesThe Prostate, EarlyView.
ABSTRACT Introduction PSMA‐PET offers an opportunity to reduce the mischaracterization of disease in active surveillance (AS) and focal therapy (FT) candidates. We describe the results of a pilot clinical trial evaluating 18F‐radiohybrid(rh)PSMA‐7.3‐PET/MRI to detect occult adverse pathology among potential AS and FT candidates (NCT05852041).
Ridwan Alam   +11 more
wiley   +1 more source

Mass balance, pharmacokinetics, metabolism, and excretion of radiolabeled acoziborole, a potential novel treatment for human African trypanosomiasis, following single microtracer oral dose to humans. [PDF]

open access: yesAntimicrob Agents Chemother
Gillon J-Y   +11 more
europepmc   +1 more source

A minimal physiologically‐based pharmacokinetic modeling platform to predict intratumor exposure and receptor occupancy of an anti‐LAG‐3 monoclonal antibody

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 460-473, March 2025.
Abstract In oncology drug development, measuring drug concentrations at the tumor site and at the targeted receptor remains an ongoing challenge. Positron emission tomography (PET)‐imaging is a promising noninvasive method to quantify intratumor exposure of a radiolabeled drug (biodistribution data) and target saturation by treatment doses in vivo ...
Robin Michelet   +8 more
wiley   +1 more source

Histopathological evaluation of local effects of radioactive iodine seeds in axillary lymph nodes in clinically node-positive breast cancer treated with neoadjuvant systemic therapy. [PDF]

open access: yesBreast
van Amstel FJG   +13 more
europepmc   +1 more source

Mechanisms Underlying Cedazuridine-Mediated Enhancement of Oral Decitabine Bioavailability. [PDF]

open access: yesCancer Res Commun
Anabtawi N   +12 more
europepmc   +1 more source

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