Results 121 to 130 of about 37,305 (281)

Isoform Specificity of a Compound Targeting Actin Filaments Containing Tropomyosin Tpm1.8/1.9

open access: yesCytoskeleton, EarlyView.
ABSTRACT The unbranched actin filaments in mammalian cells are usually composed of co‐polymers of a specific tropomyosin isoform with actin. Genetic manipulation has revealed that the tropomyosins largely define the functional properties of actin filaments in an isoform‐specific, non‐redundant manner.
Jeff Hook   +2 more
wiley   +1 more source

Advances in Human Mass Balance Studies: An IQ Consortium Perspective on Current Practices and Emerging Trends

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Human radiolabeled mass balance studies are crucial for comprehensively characterizing the absorption, distribution, metabolism, and excretion (ADME) of investigational drugs, providing essential data for drug development, regulatory evaluation, and product labeling.
Jason Boer   +24 more
wiley   +1 more source

Permeability of granite from a shallow buried mountain pipe gallery tunnel under unloading confining pressure

open access: yesDeep Underground Science and Engineering, EarlyView.
Triaxial compression tests under unloading confining pressure conditions were conducted to systematically analyze the permeability behavior of granite retrieved from the different classification surrounding rocks. Abstract The rock mass within mountain tunnels undergoes complex changes in permeability, strength, and deformation during tunneling ...
Xiaoyan Zhang   +4 more
wiley   +1 more source

RADIUM AND RADIOACTIVE SUBSTANCES. [PDF]

open access: yesJournal of the American Chemical Society, 1905
openaire   +1 more source

The effects of restraint on uptake of radioactive sulfate in the salivary and gastric secretions of rats with pyloric ligation [PDF]

open access: yes
The effects of restraint on the amount of nondialysable radioactive sulfate in the gastric wall and the gastric juice and saliva were investigated. It was found that restraint provokes a significant decrease in salivary radioactive sulfate. This, in turn,
Chayvialle, J. A., Lambert, R., Ruet, D.
core   +1 more source

The damage and failure mechanism of prestatically loaded rock during medium‐strain rate cyclic impact loading

open access: yesDeep Underground Science and Engineering, EarlyView.
Based on experimental results and theoretical analysis, an established rock damage accumulation model that comprehensively considers the preapplied static load, impact peak value, impact frequency, and impact times. Abstract To study the rock damage mechanism under high static loading and superimposed medium strain rate cyclic impact loading, a series ...
Wei Wang   +6 more
wiley   +1 more source

Interactions Between O‐Phospho‐L‐Serine and Trivalent Metal Ions: Studies in Solution and Solid State

open access: yesEuropean Journal of Inorganic Chemistry, EarlyView.
The interaction between the phosphorylated amino acid O‐phospho‐L‐serine and trivalent ions of f‐elements such as La3+, Eu3+, and Lu3+, supplemented by Y3+, has been studied in aqueous media. Nuclear magnetic resonance (NMR) spectroscopy in solution and in the solid state examined complex formation from the ligand perspective, while time‐resolved laser‐
Jonas Kunigkeit   +7 more
wiley   +1 more source

Phosphate and fluoride removal options for Hanford high‐level waste sludge processing

open access: yesEnvironmental Progress &Sustainable Energy, EarlyView.
Abstract High‐phosphate and high‐fluoride sludges represent some of the most challenging waste streams within the Hanford High‐Level Waste (HLW) inventory due to solubility constraints, impacts on glass loading, and corrosion risks during vitrification.
A. M. Westesen   +4 more
wiley   +1 more source

Epilepsy surgery: From bench to the clinics

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Recent advances in epilepsy surgery in patients with intractable epilepsy make it possible to study the mechanism of epilepsy in human brains. However, the true extent and propagation of each epileptogenic area from the epileptogenic focus in each patient is still difficult to perform “epilepsy cure” by surgery.
Tatsuya Tanaka
wiley   +1 more source

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