Results 51 to 60 of about 11,524,538 (332)

A curated binary pattern multitarget dataset of focused ATP-binding cassette transporter inhibitors

Scientific Data, 2022
Measurement(s) Influx • Efflux • Tracer • Transport velocity Technology Type(s) Fluorometry • Radioactivity • Plate reader • Flow cytometer • Tracer distribution Factor Type(s) half-maximal inhibition concentration Sample Characteristic - Organism Homo ...
Sven Marcel Stefan, Patric Jan Jansson, Jens Pahnke, Vigneshwaran Namasivayam   +3 more
doaj   +1 more source

Integrating Machine Learning With Constant‐Potential Simulation to Unravel Charge‐Transfer Mechanisms in Electrochemical Nitrogen Fixation

Advanced Science, EarlyView.
Integrating interpretable machine learning with the fixed‐potential method reveals a novel mechanism: the catalytic activity of the electrochemical nitrogen reduction reaction is governed by partial charge transfer, induced by variations in the intermediate potential of zero charge under constant potential.
Yufei Xue, Dushuo Feng, Yuefei Zhang, Yang Zhang, Yalong Jiao, Aijun Du, Guoping Gao   +6 more
wiley   +1 more source

Early Retinal UCHL1 Dysregulation Coupled With Synaptic Loss Reflects Alzheimer's Disease Severity

Advanced Science, EarlyView.
This study identifies synapse‐enriched deubiquitinase UCHL1 as an early Aβ‐responsive regulator of retinal synaptopathy in Alzheimer's disease. Retinal UCHL1 loss accompanies excitatory synapse degeneration, p75NTR activation, and neuroinflammation, and predicts Braak stage and cognitive decline. Aβ42 fibrils trigger synaptic and UCHL1 depletion before
Altan Rentsendorj, Jean‐Philippe Vit, Alexandre Hutton, Yosef Koronyo, Saba Shahin, Edward Robinson, Ernesto Barron, Anthony Rodriguez, Ousman Jallow, Julia Sheyn, Bhakta Prasad Gaire, Lalita Subedi, Miyah R. Davis, Barathan Gnanabharathi, Alexander V. Ljubimov, Stuart L. Graham, Vivek K. Gupta, Mehdi Mirzaei, Debra Hawes, Katlin Silm, Keith L. Black, Lon S. Schneider, Alfredo A. Sadun, Jesse G. Meyer, Dieu‐Trang Fuchs, Maya Koronyo‐Hamaoui   +25 more
wiley   +1 more source

The in vitro incorporation of acetate- 1 -C14 into normal and leukemic leukocyte lipids

Journal of Lipid Research, 1962
White blood cells and plasma from normal and leukemic subjects were incubated in the presence of acetate-1-C14. The distribution of radioactivity in six lipid fractions of cells and plasma was measured.
B. Malamos, C. Miras, G. Levis, J. Mantzos   +3 more
doaj   +1 more source

Distribution of 14C-Latanoprost Following a Single Intracameral Administration Versus Repeated Topical Administration

Ophthalmology and Therapy, 2020
Purpose To qualitatively evaluate the ocular and periocular distribution of 14C-latanoprost following a single intracameral administration or repeated topical ocular administration in beagle dogs and cynomolgus monkeys.
Jie Shen, Rex A. Moats, Harvey A. Pollack, Michael R. Robinson, Mayssa Attar   +4 more
doaj   +1 more source

RADIOELEMENTS DISTRIBUTION IN GABAL ABU-MESAID AREA, NORTH EASTERN DESERT, EGYPT [PDF]

Delta Journal of Science, 2007
A suite of volcanic and plutonic rocks represent the products of Pan-African orogeny; constitute the major litho-tectonic units of Gabal Abu-Mesaid area, in the northern part of the Eastern Desert.
H.I.A. FARAG, M.A. EL-TAHIR, L.M. NOSSAIR, A. ABU-DEIF   +3 more
doaj   +1 more source

Comrade Black Distribution [February 1998 catalogue]

, 1998
The catalog of a D.I.Y. retail distributor of political and small press books and pamphlets. Started in 1996, CB Distribution is an effort to counter the homogeneity of political and artistic thought that dominates the mainstream media.
Comrade Black Distribution
core   +1 more source

Ultra‐Radiostable Covalent Conformationally Interlocked Networks Enabling a Universal Radiometal‐Labeling Platform for Cancer Radioembolization

Advanced Science, EarlyView.
Conjugated poly(imide dioxime)‐based microspheres establish a radiometal coordination‐driven conformational interlocked network with ultra‐high radiostability. This platform enables low‐temperature, multi‐radionuclide labeling for SPECT/PET/MRI imaging and radionuclide therapy. Mechanistic insights from EXAFS and DFT reveal enhanced stability, while in
Xiao Xu, Zhenwen Zhao, Yangjie Wang, Zhigang Liu, Zhijie Liu, Xiaoling Li, Zhichen Mao, Lu Xu, Gan Lin, Gang Liu, Hongjuan Ma   +10 more
wiley   +1 more source

Metabolism of methyl elaidate*

Journal of Lipid Research, 1962
Methyl elaidate-l-C14 was fed to fat-deficient guinea pigs. Very little incorporation of the radioactivity was found in the glycerides or phospholipids under these conditions.
G.A. Dhopeshwarkar, James F. Mead
doaj   +1 more source

Radioactivity and measurements of sediment deposition rate of the Drenova reservoir (B&H) [PDF]

Nuclear Technology and Radiation Protection, 2012
This work presents the first estimate of the radioactivity and sediment deposition rate of the Drenova reservoir. The radioactivity and sedimentation rate were computed applying the 210Pb and 137Cs methods.
Tošić Radislav, Todorović Dragana J., Dragićević Slavoljub S., Bikit Ištvan S., Forkapić Sofija, Blagojević Branislav   +5 more
doaj   +1 more source