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In addition to the physical advantages (Bragg peak), the use of charged particles in cancer therapy can be associated with distinct biological effects compared to X-rays. While heavy ions (densely ionizing radiation) are known to have an energy- and charge-dependent increased Relative Biological Effectiveness (RBE), protons should not be very ...
Tommasino F., Durante M.
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Radiotherapy using accelerated charged particles is rapidly growing worldwide. About 85% of the cancer patients receiving particle therapy is irradiated with protons, which have physical advantages compared to X-rays but similar biological response. In addition to the ballistic advantages, heavy ions present specific radiobiological features that can ...
Tinganelli W., Durante M.
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A High-Throughput In Vitro Radiobiology Platform for Megavoltage Photon Linear Accelerator Studies
We designed and developed a multiwell tissue culture plate irradiation setup, and intensity modulated radiotherapy plans were generated for 96-, 24-, and 6-well tissue culture plates.
Kamalram Thippu Jayaprakash +6 more
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Preparing for a “dirty bomb” attack: the optimum mix of medical countermeasure resources
Background In radiological emergencies with radionuclide incorporation, decorporation treatment is particularly effective if started early. Treating all people potentially contaminated (“urgent treatment”) may require large antidote stockpiles.
Alexis Rump +5 more
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Radiobiology and treatment plan progress of FLASH radiotherapy
FLASH radiotherapy is a novel method that has the potential to improve the therapeutic gain ratio to a new level. FLASH radiotherapy technology is mainly characterized by irradiation at ultra-high dose rate, which can reduce radiation-induced injury to ...
WU Xun +3 more
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Limitations in Predicting the Space Radiation Health Risk for Exploration Astronauts [PDF]
Despite years of research, understanding of the space radiation environment and the risk it poses to long-duration astronauts remains limited. There is a disparity between research results and observed empirical effects seen in human astronaut crews ...
Auñón-Chancellor, Serena M. +6 more
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The study of the biologic effects of space radiation is considered a “hot topic,” with increased interest in the past years. In this chapter, the unique characteristics of the space radiation environment will be covered, from their history, characterization, and biological effects to the research that has been and is being conducted in the field. After
Hellweg, Christine +24 more
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Towards Laser Driven Hadron Cancer Radiotherapy: A Review of Progress [PDF]
It has been known for about sixty years that proton and heavy ion therapy is a very powerful radiation procedure for treating tumours. It has an innate ability to irradiate tumours with greater doses and spatial selectivity compared with electron and ...
Bolton, P. R. +3 more
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