Results 31 to 40 of about 19,268 (172)

Emerging Applications for Optically Enabled Intravital Microscopic Imaging in Radiobiology

Molecular Imaging, 2015
Radiation therapy is an effective cancer treatment used in over 50% of cancer patients. Preclinical research in radiobiology plays a major role in influencing the translation of radiotherapy-based treatment strategies into clinical practice. Studies have
Azusa Maeda, Iris Kulbatski, Ralph S. DaCosta   +2 more
doaj   +1 more source

Flash Radiotherapy: Innovative Cancer Treatment

Encyclopedia, 2023
Flash radiotherapy (Flash-RT) is an innovative technique used in radiotherapy for cancer treatment because it delivers an extremely high dose of radiation (>40 Gy/s) to the tumour in a very short period of time, typically within a fraction of a second ...
James C. L. Chow, Harry E. Ruda
doaj   +1 more source

²²⁵Ac-Labeled Somatostatin Analogs in the Management of Neuroendocrine Tumors: From Radiochemistry to Clinic

Pharmaceutics, 2023
The widespread use of peptide receptor radionuclide therapy (PRRT) represents a major therapeutic breakthrough in nuclear medicine, particularly since the introduction of 177Lu-radiolabeled somatostatin analogs. These radiopharmaceuticals have especially
Léa Rubira, Emmanuel Deshayes, Lore Santoro, Pierre Olivier Kotzki, Cyril Fersing   +4 more
doaj   +1 more source

Radiation‐Triggered Chemokine‐Secreting Probiotics for Boron Neutron Capture Therapy Based Radioimmunotherapy

Advanced Science, EarlyView.
Engineered Escherichia coli Nissle 1917 with a tannic acid‐mediated BPA coating enables tumor‐targeted boron delivery for BNCT. The low‐level incidental radiation generated during BNCT activate a RecA‐driven circuit to induce CXCL10, while radiation‐enhanced bacterial colonization triggers in situ vaccination and systemic antitumor immunity.
Yang Liu, Yuzhong Qian, Shaobo Huang, Bingbing Li, Yue Yu, Xiang Cheng, Chang Chen, Jiheng Wang, Maosong Yang, Lizheng Liang, Xiancai Meng, Zhigang Liu   +11 more
wiley   +1 more source

Selective Cell‐Repellent 3D Scaffold Platform for Proton Radiobiology

Advanced NanoBiomed Research, EarlyView.
A selective cell‐repellent 3D scaffold platform is developed to minimize unwanted 2D cell populations surrounding engineered cell microenvironments. The approach is based on the combination of Lipidure coatings with two‐photon polymerized scaffolds and enables specific characterization of glioblastoma cells’ response to proton irradiation.
Novinda S. Pertiwi, Qais Akolawala, Rob van den Akker, Anggraeini Puspitasari‐Kokko, Henri H. Versteeg, Araci M. R. Rondon, Angelo Accardo   +6 more
wiley   +1 more source

Transcriptome and proteome analyses reveal divergent adaptive strategies in nasopharyngeal epithelial cells and nasopharyngeal carcinoma cells under ultra‐low background radiation

Deep Underground Science and Engineering, EarlyView.
This study demonstrates that the ultra‐low background radiation environment in deep underground laboratories significantly inhibits the proliferation of both normal nasopharyngeal epithelial cells (HNEPC) and nasopharyngeal carcinoma cells (HNE‐1) cells, with malignant cells exhibiting higher sensitivity.
Yuhao Zou, Qi Wu, Jirui Wen, Ling Wang, Can Li, Juan Cheng, Tengfei Ma, Chuhan Lv, Shixi Liu, Mingzhong Gao, Ruihua Dong, Jianxiong Zhang, Jingxuan Wu, Heping Xie, Jiang Wu, Jifeng Liu   +15 more
wiley   +1 more source

Artificial intelligence in radiobiology: Bridging mechanisms and data analysis

Radiation Medicine and Protection
The rapid development of artificial intelligence (AI) technology is profoundly transforming research paradigms in radiobiology. By integrating multimodal data, AI models have significantly enhanced both the efficiency and accuracy of elucidating complex ...
Yahe Wang, Wenfeng Li, Nanxin Xu, Dafei Xie, Xin Huang, Ping-Kun Zhou   +5 more
doaj   +1 more source

Dynamic control of carbon‐ion radiation dose distribution amid respiratory motion challenges: A review of prediction research using geant4 and deep learning physics‐constrained models

Journal of Applied Clinical Medical Physics, Volume 27, Issue 11, November 2026.
Abstract Background Carbon ion radiotherapy (CIRT) offers superior dose conformity and biological effectiveness; however, its precision is highly sensitive to respiratory motion, leading to dose uncertainty and interplay effects that compromise treatment accuracy.
Jianhua Ding, Peng Li, Chai Hong Yeong
wiley   +1 more source

National Radiobiology Archives Distributed Access user's manual [PDF]

, 1991
This User's Manual describes installation and use of the National Radiobiology Archives (NRA) Distributed Access package. The package consists of a distributed subset of information representative of the NRA databases and database access software which ...
Watson, C., Smith, S. (Pacific Northwest Lab., Richland, WA (United States)), Prather, J. (Linfield Coll., McMinnville, OR (United States))   +2 more
core   +1 more source

Challenges in radiobiology – technology duality as a key for a risk-free α/β ratio

, 2023
International audienceSince radiotherapy discovery, prediction of biological response to ionizing radiation remains a major challenge. Indeed, several radiobiological models appeared through radiotherapy history.
Wafa Bouleftour, Nicolas Magné, Jean-Baptiste Guy, Magné, Nicolas, Claire Rodriguez Lafrasse, Paul Sargos, Pablo Moreno-Acosta, Sargos, Paul, Bouleftour, Wafa, Rodriguez Lafrasse, Claire, Moreno-Acosta, Pablo, Guy, Jean-Baptiste   +11 more
core   +1 more source