Results 41 to 50 of about 15,376 (161)

Cancer Cells Can Exhibit a Sparing FLASH Effect at Low Doses Under Normoxic In Vitro-Conditions

Frontiers in Oncology, 2021
BackgroundIrradiation with ultra-high dose rate (FLASH) has been shown to spare normal tissue without hampering tumor control in several in vivo studies. Few cell lines have been investigated in vitro, and previous results are inconsistent. Assuming that
Gabriel Adrian, Gabriel Adrian, Elise Konradsson, Sarah Beyer, Anders Wittrup, Anders Wittrup, Anders Wittrup, Karl T. Butterworth, Stephen J. McMahon, Mihaela Ghita, Kristoffer Petersson, Kristoffer Petersson, Crister Ceberg   +12 more
doaj   +1 more source

In‐House Production of POFs Using Electrospinning, Melt‐Electrospinning and Melt‐Spinning for Cell‐Level Resolution Radiation Detectors

Journal of Applied Polymer Science, Volume 142, Issue 48, December 20, 2025.
Optical transmission along a melt‐spun polystyrene microfiber with a diemeter of 80 um. ABSTRACT Since their discovery in 1965, scintillating plastic optical fibers have been used as radiation detectors in nuclear and high‐energy physics research.
Cristiana M. C. Rodrigues, Luís Peralta, António P. Gonçalves, José M. Figueiredo, Duarte R. Guerreiro, Jorge M. Sampaio, João G. Saraiva   +6 more
wiley   +1 more source

Editorial: The Biogeochemistry, Biophysics, Radiobiology, and Technical Challenges of Deep Subsurface Research [PDF]

, 2021
Geoffrey B. Smith, Maria Antonella Tabocchini, C. Peña‐Garay   +2 more
openalex   +1 more source

Review of the anatomical basis for predicting plutonium alpha particle radiation induced osteogenic cancers

The Anatomical Record, Volume 308, Issue 12, Page 3197-3229, December 2025.
Abstract Plutonium was discovered and first synthesized in the early 1940's. Several isotopes of plutonium are used in nuclear technologies, 238Pu for heat generation and 239Pu for energy production and weapons. Both isotopes emit alpha particles, which pose a significant radiation hazard when incorporated into the body.
Scott C. Miller
wiley   +1 more source

Reirradiation: Standards, challenges, and patient‐focused strategies across tumor types

CA: A Cancer Journal for Clinicians, Volume 75, Issue 6, Page 630-666, November/December 2025.
Abstract Reirradiation (reRT), defined as administering a course of radiation therapy to a specific area previously irradiated, is an evolving treatment strategy for locoregionally recurrent cancer that offers significant potential and poses inherent challenges.
Arnaud Beddok, Jonas Willmann, Anna Embring, Ane L. Appelt, Panagiotis Balermpas, Kevin Chua, J. Isabelle Choi, Bernice Simone Elger, Dorota Gabrys, Peter Hoskin, Maximilian Niyazi, David Pasquier, Kelly Paradis, Orit Kaidar‐Person, Corien Plaisier, Nicole C. Schmitt, Conor E. Steuer, Juliette Thariat, Sue S. Yom, Philip Poortmans, Eliana Vasquez Osorio, Nicolaus Andratschke   +21 more
wiley   +1 more source

An AMPK‐Centric Strategy: Foenumoside B Coordinates PINK1/Parkin‐Mediated Mitophagy With Nrf2/HO‐1 Antioxidant Signaling to Resolve Oxidative Stress in Radiation‐Induced Lung Injury

The FASEB Journal, Volume 39, Issue 22, 30 November 2025.
In RILI, FSB directly activates AMPK, thereby driving PINK1/Parkin‐mediated mitophagy and remodeling Nrf2‐mediated redox homeostasis, which in turn reduces the generation and accumulation of ROS and suppresses DNA damage and senescence in epithelial cells.
Xiaoyu Pu, Xiaodong Li, Bohao Liu, Yan Zhang   +3 more
wiley   +1 more source

Modeling of acute radiation syndrome in experiment

Радиационная гигиена
The aim of the current study was to create a new and easily reproducible method of modeling acute radiation syndrome, representing the features of the clinical flow of this disease.
A. A. Popova, L. A. Chipiga, D. N. Maystrenko, A. A. Stanzhevskiy, O. E. Molchanov, D. N. Nikolaev, T. E. Ponezha, Yu. N. Vinogradova, E. B. Ioffe   +8 more
doaj   +1 more source

Mesenchymal Colorectal Cancers Secrete Vesicles With Unique Cargo That Can Be Used for Liquid Biopsy Based Diagnostics

Journal of Extracellular Vesicles, Volume 14, Issue 11, November 2025.
ABSTRACT Tumour‐derived extracellular vesicles (TEVs) play a crucial role in cancer progression, metastasis and therapy resistance but their distinct profiles across different cancer stages and molecular subtypes remain underexplored. This study initially analysed TEVs from all CMS subtypes in colorectal cancer (CRC) cells and continued focusing on the
Paris J. Asif, Lauri H. Borghuis, Sander R. van Hooff, Anita E. Grootemaat, Monique A. J. van Eijndhoven, Johan de Rooij, Nils J. Groenewegen, Jennifer Perez Boza, Onno Kranenburg, Inne H. M. Borel Rinkes, Cristina Gómez‐Martín, Hans F. M. Pruijt, Nicole N. van der Wel, Arezo Torang, Tineke E. Buffart, D. Michiel Pegtel, Jan Paul Medema   +16 more
wiley   +1 more source

Human Endogenous Retroviruses and Diseases

MedComm, Volume 6, Issue 11, November 2025.
Human endogenous retroviruses (HERVs), remnants of ancient retroviral integrations into the human genome, are modulated by viral infections, genetic inheritance, and triggers including environmental factors, epigenetic dysregulation, oncogene activation, and aging.
Can Chen, Yanru Cui, Shixiang Wang, Yuze Yang, Zunpeng Liu, Suhan Jin, Fangqian Shen, Udo Gaipl, Hu Ma, Jian‐Guo Zhou   +9 more
wiley   +1 more source

Neutron Radiobiology and Dosimetry [PDF]

, 2021
Daniela Stricklin, Jama VanHorne-Sealy, Carmen I. Rios, Lisa A. Scott Carnell, Lanyn P. Taliaferro   +4 more
openalex   +1 more source