Results 111 to 120 of about 26,902 (278)

Preclinical comparison of four [18F, natGa]rhPSMA-7 isomers: influence of the stereoconfiguration on pharmacokinetics

open access: yesEJNMMI Research, 2020
Introduction Radiohybrid (rh) ligands, a novel class of prostate-specific membrane antigen (PSMA)-targeted radiopharmaceuticals, can be labeled either with [18F]fluorine via isotopic exchange or with radiometals (such as [68Ga]Gallium, [177Lu]Lutetium ...
Alexander Wurzer   +8 more
doaj   +1 more source

Rapid, efficient, and economical synthesis of PET tracers in a droplet microreactor: application to O-(2-[18F]fluoroethyl)-L-tyrosine ([18F]FET). [PDF]

open access: yes, 2019
BackgroundConventional scale production of small batches of PET tracers (e.g. for preclinical imaging) is an inefficient use of resources. Using O-(2-[18F]fluoroethyl)-L-tyrosine ([18F]FET), we demonstrate that simple microvolume radiosynthesis ...
Chen, Bao Ying   +5 more
core   +1 more source

Fundamental Research on Radiochemistry of Geological Nuclear Waste Disposal.

open access: yesChimia (Basel), 2020
Currently, 5 · 1019 Bq of radioactive waste originating from the use of nuclear power for energy production, and medicine, industry and research, is maintained in Switzerland at intermediate storage facilities.
S. Churakov, W. Hummel, M. M. Fernandes
semanticscholar   +1 more source

A companion to the preclinical common data elements and case report forms for in vivo rodent neuroimaging: A report of the TASK3‐WG3 Neuroimaging Working Group of the ILAE/AES Joint Translational Task Force

open access: yesEpilepsia Open, Volume 10, Issue S1, Page S136-S182, August 2025.
Abstract The International League Against Epilepsy/American Epilepsy Society (ILAE/AES) Joint Translational Task Force established the TASK3 working groups to create common data elements (CDEs) for various aspects of preclinical epilepsy research studies, which could help improve the standardization of experimental designs.
Erwin A. van Vliet   +9 more
wiley   +1 more source

High precision half-life measurement of the extinct radio-lanthanide Dysprosium-154

open access: yesScientific Reports, 2022
Sixty years after the discovery of 154Dy, the half-life of this pure alpha-emitter was re-measured. 154Dy was radiochemically separated from proton-irradiated tantalum samples. Sector field- and multicollector-inductively coupled plasma mass spectrometry
Nadine Mariel Chiera   +4 more
doaj   +1 more source

Radiolabeled Nanogels: From Multimodality Imaging to Combination Therapy of Cancer

open access: yesSmall Science, Volume 5, Issue 8, August 2025.
Nanogel refers to nanosized particles formed by physical or chemical crosslinking of polymers. Rational design and refinement of nanogel properties are imperative to unlock their full potential, ensuring tailored solutions for personalized cancer management. This review elucidates the transformative potential of radiolabeled nanogels in revolutionizing
Sanchita Ghosh   +2 more
wiley   +1 more source

Stable Isotope Reference Materials and Scale Definitions—Outcomes of the 2024 IAEA Experts Meeting

open access: yesRapid Communications in Mass Spectrometry, Volume 39, Issue 14, 30 July 2025.
ABSTRACT The participants of the 12th International Atomic Energy Agency (IAEA) meeting on stable isotope reference materials reached a consensus, acknowledging the existence and use of two carbon isotope delta scales: the VPDB (Vienna Peedee belemnite) scale and the VPDB‐LSVEC (LSVEC ‐ lithium carbonate prepared by H. J. Svec).
Federica Camin   +24 more
wiley   +1 more source

The radiochemistry of cesium

open access: yes, 1961
A comprehensive review of the chemistry and radiochemistry of cesium is presented. Dissolution of samples containing cesium is discussed, and analytical methods, counting techniques, snd radiochemical procedures are presented. Applications of cesium radioisotopes are discussed briefly. (D.L.C.)
M.T. Kinsley, H. L. Finston
openaire   +3 more sources

Comparison of visual and analytic methods of Alzheimer's disease pathologic staging

open access: yesAlzheimer's &Dementia, Volume 21, Issue 7, July 2025.
Abstract INTRODUCTION Methods for standardizing positron emission tomography (PET) indices of β‐amyloid (Aβ) (Centiloid [CL]) and tau (CenTauRz, CTRz) burden facilitates direct comparisons across radiotracers and supports in vivo biologic staging per the AT(N) (Aβ [A], tau [T], and neurodegeneration [N]) framework.
Brian J. Lopresti   +12 more
wiley   +1 more source

Impact of intracellular radionuclide distribution in a Monte Carlo biophysical 3D multi‐cellular model for targeted alpha therapy

open access: yesMedical Physics, Volume 52, Issue 7, July 2025.
Abstract Background To understand and predict the therapeutic efficacy of targeted alpha therapy (TAT), nano‐ and microdosimetry are needed to consider the very heterogeneous dose deposition at cellular and subcellular levels. Purpose The objective of this study is to theoretically evaluate the importance of cell internalization of alpha‐emitters on ...
Victor Levrague   +6 more
wiley   +1 more source

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