Results 11 to 20 of about 12,648 (203)
<sup>18</sup>F-Radiopharmaceutical Diversification Enabled by Deaminative Cross-Electrophile Couplings. [PDF]
Angew Chem Int Ed EnglA general Ni‐mediated (C)sp2–(C)sp3 cross‐coupling expedites access to 18F‐radiopharmaceuticals, essential for positron emission tomography imaging and drug discovery. This late‐stage diversification approach was implemented across three user‐friendly automated protocols affording 18F‐radiotracers in sufficient quantities for imaging.
Ogilvy IF +13 more
europepmc +2 more sources
One-Pot Base-Free Suzuki-Miyaura [<sup>11</sup>C]Methylation: Kinetic and Mechanistic Insights. [PDF]
ChemistryA base‐free Suzuki–Miyaura [11C]methylation is achieved in a one‐pot process with [11C]CH3I on moderate yields. Electronic effects enable transmetallation without boronate activation, while kinetics and DFT show oxidative addition (heterolytic) as the rate‐limiting step.
Moreno O +4 more
europepmc +2 more sources
Cerenkov Luminescence Imaging in the Development and Production of Radiopharmaceuticals
Frontiers in Physics, 2021 Over the past several years there has been an explosion of interest in exploiting Cerenkov radiation to enable in vivo and intraoperative optical imaging of subjects injected with trace amounts of radiopharmaceuticals.
R. Michael van Dam +3 more
doaj +1 more source
Radiochemistry: A Hot Field with Opportunities for Cool Chemistry
ACS Central Science, 2023 Recent Food and Drug Administration (FDA) approval of diagnostic and therapeutic radiopharmaceuticals and concurrent miniaturization of particle accelerators leading to improved access has fueled interest in the development of chemical transformations ...
G. Bowden, Pete Scott, E. Boros
semanticscholar +1 more source
Analysis into the viability of pea gravel as a diffusing material for biostimulation systems in petroleum hydrocarbon-contaminated soils. [PDF]
J Environ QualAbstract Injecting biostimulatory solutions around underground storage tanks (UGSTs) promotes petroleum hydrocarbon (PHC) bioremediation without the use of intrusive infrastructure. Yet, it is unclear how the interaction between porous bedding material (i.e., pea gravel) and biostimulatory solutions impacts PHC biodegradation rates.
Schryer AD +3 more
europepmc +2 more sources
Pharmaceutics, 2023 The widespread use of peptide receptor radionuclide therapy (PRRT) represents a major therapeutic breakthrough in nuclear medicine, particularly since the introduction of 177Lu-radiolabeled somatostatin analogs. These radiopharmaceuticals have especially
Léa Rubira +4 more
semanticscholar +1 more source
Design and Manufacture of a Test Device for Radiosynthesizer Vacuum Pumps
Instruments, 2023 Vacuum pump wear is the most prevalent failure mode of the IBA Synthera® automated radiochemistry system. Rebuilding or replacing the pump causes equipment downtime and increases the radiation exposure of the service personnel.
Victor Amador Diaz +2 more
doaj +1 more source
EJNMMI Radiopharmacy and Chemistry, 2021 Background The Editorial Board of EJNMMI Radiopharmacy and Chemistry releases a biyearly highlight commentary to describe trends in the field. Results This commentary of highlights has resulted in 19 different topics selected by each member of the ...
Mohammed Al-Qahtani +18 more
doaj +1 more source
Pharmaceuticals, 2023 The Pd–Xantphos-mediated 11C-carbonylation protocol (also known as the “Xantphos- method”), due to its simplistic and convenient nature, has facilitated researchers in meeting a longstanding need for preparing 11C-carbonyl-labeled radiopharmaceuticals at
Kenneth Dahl +3 more
doaj +1 more source
Highlight selection of radiochemistry and radiopharmacy developments by editorial board
EJNMMI Radiopharmacy and Chemistry, 2021 Background The Editorial Board of EJNMMI Radiopharmacy and Chemistry releases a biyearly highlight commentary to update the readership on trends in the field of radiopharmaceutical development.
Silvio Aime +22 more
doaj +1 more source