Results 11 to 20 of about 24,433 (235)

One-Pot Base-Free Suzuki-Miyaura [¹¹C]Methylation: Kinetic and Mechanistic Insights. [PDF]

Chemistry
A base‐free Suzuki–Miyaura [11C]methylation is achieved in a one‐pot process with [11C]CH3I on moderate yields. Electronic effects enable transmetallation without boronate activation, while kinetics and DFT show oxidative addition (heterolytic) as the rate‐limiting step.
Moreno O, Azzeggarh I, Holland JP, Windhorst AD, Llop J.   +4 more
europepmc   +2 more sources

Analysis into the viability of pea gravel as a diffusing material for biostimulation systems in petroleum hydrocarbon-contaminated soils. [PDF]

J Environ Qual
Abstract Injecting biostimulatory solutions around underground storage tanks (UGSTs) promotes petroleum hydrocarbon (PHC) bioremediation without the use of intrusive infrastructure. Yet, it is unclear how the interaction between porous bedding material (i.e., pea gravel) and biostimulatory solutions impacts PHC biodegradation rates.
Schryer AD, Alvarez Ruiz A, Bradshaw K, Siciliano SD.   +3 more
europepmc   +2 more sources

Highlight selection of radiochemistry and radiopharmacy developments by editorial board (January–June 2020)

EJNMMI Radiopharmacy and Chemistry, 2021
Background The Editorial Board of EJNMMI Radiopharmacy and Chemistry releases a biyearly highlight commentary to describe trends in the field. Results This commentary of highlights has resulted in 19 different topics selected by each member of the ...
Mohammed Al-Qahtani, Martin Behe, Guy Bormans, Giuseppe Carlucci, Jean Dasilva, Clemens Decristoforo, Philip H. Elsinga, Klaus Kopka, Xiang-Guo Li, Robert Mach, Oskar Middel, Jan Passchier, Marianne Patt, Ivan Penuelas, Ana Rey, Peter J. H. Scott, Sergio Todde, Jun Toyohara, Danielle Vugts   +18 more
doaj   +1 more source

Reactive Palladium–Ligand Complexes for ¹¹C-Carbonylation at Ambient Pressure: A Breakthrough in Carbon-11 Chemistry

Pharmaceuticals, 2023
The Pd–Xantphos-mediated 11C-carbonylation protocol (also known as the “Xantphos- method”), due to its simplistic and convenient nature, has facilitated researchers in meeting a longstanding need for preparing 11C-carbonyl-labeled radiopharmaceuticals at
Kenneth Dahl, Anton Lindberg, Neil Vasdev, Magnus Schou   +3 more
doaj   +1 more source

Highlight selection of radiochemistry and radiopharmacy developments by editorial board

EJNMMI Radiopharmacy and Chemistry, 2021
Background The Editorial Board of EJNMMI Radiopharmacy and Chemistry releases a biyearly highlight commentary to update the readership on trends in the field of radiopharmaceutical development.
Silvio Aime, Mohammed Al-Qahtani, Martin Behe, Guy Bormans, Giuseppe Carlucci, Jean N. DaSilva, Clemens Decristoforo, Adriano Duatti, Philip H. Elsinga, Klaus Kopka, Xiang-Guo Li, Zhibo Liu, Robert H. Mach, Oskar Middel, Jan Passchier, Marianne Patt, Ivan Penuelas, Ana Rey, Peter J. H. Scott, Sergio Todde, Jun Toyohara, Danielle Vugts, Zhi Yang   +22 more
doaj   +1 more source

Preparation, Optimisation, and In Vitro Evaluation of [¹⁸F]AlF-NOTA-Pamidronic Acid for Bone Imaging PET

Molecules, 2022
[18F]sodium fluoride ([18F]NaF) is recognised to be superior to [99mTc]-methyl diphosphate ([99mTc]Tc-MDP) and 2-deoxy-2-[18F]fluoro-D-glucose ([18F]FDG) in bone imaging. However, there is concern that [18F]NaF uptake is not cancer-specific, leading to a
Hishar Hassan, Muhamad Faiz Othman, Hairil Rashmizal Abdul Razak, Zainul Amiruddin Zakaria, Fathinul Fikri Ahmad Saad, Mohd Azuraidi Osman, Loh Hui Yi, Zarif Ashhar, Jaleezah Idris, Mohd Hamdi Noor Abdul Hamid, Zaitulhusna M. Safee   +10 more
doaj   +1 more source

Silicon-[18F]Fluorine Radiochemistry: Basics, Applications and Challenges

Applied Sciences, 2012
Silicon-[18F]fluorine (Si-18F) radiochemistry has recently emerged alongside other unconventional approaches such as aluminum-18F and boron-18F based labeling strategies, reshaping the landscape of modern 18F-radiochemistry. All these novel methodologies
Carmen Wängler, Alexey Kostikov, Jun Zhu, Joshua Chin, Björn Wängler, Ralf Schirrmacher   +5 more
doaj   +1 more source

Fully Automated GMP-Compliant Synthesis of [¹⁸F]FE-PE2I

Pharmaceuticals, 2021
In the struggle to understand and accurately diagnose Parkinson′s disease, radiopharmaceuticals and medical imaging techniques have played a major role. By being able to image and quantify the dopamine transporter density, noninvasive diagnostic imaging ...
Klas Bratteby, Charlotte Lund Denholt, Szabolcs Lehel, Ida Nymann Petersen, Jacob Madsen, Maria Erlandsson, Tomas Ohlsson, Matthias Manfred Herth, Nic Gillings   +8 more
doaj   +1 more source

Enzymatic transhalogenation of dendritic RGD peptide constructs with the fluorinase [PDF]

, 2016
We thank EPSRC and the Scottish Imaging Network (SINAPSE) for grants. DO’H thanks the Royal Society for a Wolfson Research Merit Award and ST is grateful to the John and Kathleen Watson Scholarship for financial support.
Fleming, Ian N., O’Hagan, David, Thompson, Stephen   +2 more
core   +1 more source

Thorotrast and in vivo thorium dioxide: numerical simulation of 30 years of alpha radiation absorption by the tissues near a large compact source [PDF]

, 2014
Background: The epidemiology of the slightly radioactive contrast agent named Thorotrast presents a very long latency period between the injection and the development of the related pathologies.
Bianconi, Andrea
core   +2 more sources