Results 21 to 30 of about 22,957 (141)

Rapid iododeboronation with and without gold catalysis: application to radiolabelling of arenes [PDF]

open access: yes, 2017
Radiopharmaceuticals incorporating radioactive iodine in combination with SPECT imaging play a key role in nuclear medicine, with applications in drug development and disease diagnosis.
Fletcher, Conor   +5 more
core   +2 more sources

The Metamorphosis of Radionuclide Production and Development at Paul Scherrer Institute

open access: yesCHIMIA, 2020
Radionuclide production and development has a long history at the Paul Scherrer Institute (PSI) and dates back to the founding times of its forerunner institutions: the Federal Institute for Reactor Research and the Swiss Institute for Nuclear Research ...
Pascal V. Grundler   +5 more
doaj   +1 more source

Evaluation of [64Cu]Cu-NOTA-PEG7-H-Tz for Pretargeted Imaging in LS174T Xenografts—Comparison to [111In]In-DOTA-PEG11-BisPy-Tz

open access: yesMolecules, 2021
Pretargeted nuclear imaging for the diagnosis of various cancers is an emerging and fast developing field. The tetrazine ligation is currently considered the most promising reaction in this respect. Monoclonal antibodies are often the preferred choice as
Christian B. M. Poulie   +6 more
doaj   +1 more source

Highlight selection of radiochemistry and radiopharmacy developments by editorial board

open access: yesEJNMMI Radiopharmacy and Chemistry, 2022
Background The Editorial Board of EJNMMI Radiopharmacy and Chemistry releases a biannual highlight commentary to update the readership on trends in the field of radiopharmaceutical development.
Jun Toyohara   +20 more
doaj   +1 more source

Novel Receptor Tyrosine Kinase Pathway Inhibitors for Targeted Radionuclide Therapy of Glioblastoma

open access: yesPharmaceuticals, 2021
Glioblastoma (GB) remains the most fatal brain tumor characterized by a high infiltration rate and treatment resistance. Overexpression and/or mutation of receptor tyrosine kinases is common in GB, which subsequently leads to the activation of many ...
Julie Bolcaen   +5 more
doaj   +1 more source

Thorotrast and in vivo thorium dioxide: numerical simulation of 30 years of alpha radiation absorption by the tissues near a large compact source [PDF]

open access: yes, 2014
Background: The epidemiology of the slightly radioactive contrast agent named Thorotrast presents a very long latency period between the injection and the development of the related pathologies.
Bianconi, Andrea
core   +2 more sources

The Rise of Synaptic Density PET Imaging

open access: yesMolecules, 2020
Many neurological disorders are related to synaptic loss or pathologies. Before the boom of positrons emission tomography (PET) imaging of synapses, synaptic quantification could only be achieved in vitro on brain samples after autopsy or surgical ...
Guillaume Becker   +3 more
doaj   +1 more source

Synthesis of Novel, Dual-Targeting 68Ga-NODAGA-LacN-E[c(RGDfK)]2 Glycopeptide as a PET Imaging Agent for Cancer Diagnosis

open access: yesPharmaceutics, 2021
Radiolabeled peptides possessing an Arg-Gly-Asp (RGD) motif are widely used radiopharmaceuticals for PET imaging of tumor angiogenesis due to their high affinity and selectivity to αvβ3 integrin.
Barbara Gyuricza   +6 more
doaj   +1 more source

Environmental Radiochemistry

open access: yesHe huaxue yu fangshe huaxue
Environmental radiochemistry is a basic and applicative science, which was born with the combination of radiochemistry and environmental sciences, and she was coming to be a branch of sciences with the human’s concerns of the health effects of ...
Chun-li LIU   +5 more
doaj   +1 more source

Radiotracers for Imaging of Fibrosis: Advances during the Last Two Decades and Future Directions

open access: yesPharmaceuticals, 2023
Fibrosis accompanies various pathologies, and there is thus an unmet medical need for non-invasive, sensitive, and quantitative methods for the assessment of fibrotic processes.
Olof Eriksson, Irina Velikyan
doaj   +1 more source

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