Results 11 to 20 of about 22,957 (141)

25 Years of "Loop" Radiochemistry for PET Imaging. [PDF]

open access: yesJ Labelled Comp Radiopharm
While conventional methods to 11C‐ and 18F‐labelled radiopharmaceuticals utilize a vial‐based approach, in the past quarter‐century, a modern, efficient, and cleaner “loop method” has been developed. The radiochemical diversity of reactions synthesized by the loop method are shown.
Murrell E, Khan S, Vasdev N.
europepmc   +2 more sources

Fully Automated GMP-Compliant Synthesis of [18F]FE-PE2I

open access: yesPharmaceuticals, 2021
In the struggle to understand and accurately diagnose Parkinson′s disease, radiopharmaceuticals and medical imaging techniques have played a major role. By being able to image and quantify the dopamine transporter density, noninvasive diagnostic imaging ...
Klas Bratteby   +8 more
doaj   +1 more source

Highlight selection of radiochemistry and radiopharmacy developments by editorial board

open access: yesEJNMMI Radiopharmacy and Chemistry, 2023
Background The Editorial Board of EJNMMI Radiopharmacy and Chemistry releases a biannual highlight commentary to update the readership on trends in the field of radiopharmaceutical development.
Jean DaSilva   +21 more
doaj   +1 more source

Preparation, Optimisation, and In Vitro Evaluation of [18F]AlF-NOTA-Pamidronic Acid for Bone Imaging PET

open access: yesMolecules, 2022
[18F]sodium fluoride ([18F]NaF) is recognised to be superior to [99mTc]-methyl diphosphate ([99mTc]Tc-MDP) and 2-deoxy-2-[18F]fluoro-D-glucose ([18F]FDG) in bone imaging. However, there is concern that [18F]NaF uptake is not cancer-specific, leading to a
Hishar Hassan   +10 more
doaj   +1 more source

Silicon-[18F]Fluorine Radiochemistry: Basics, Applications and Challenges

open access: yesApplied Sciences, 2012
Silicon-[18F]fluorine (Si-18F) radiochemistry has recently emerged alongside other unconventional approaches such as aluminum-18F and boron-18F based labeling strategies, reshaping the landscape of modern 18F-radiochemistry. All these novel methodologies
Carmen Wängler   +5 more
doaj   +1 more source

Reactive Palladium–Ligand Complexes for 11C-Carbonylation at Ambient Pressure: A Breakthrough in Carbon-11 Chemistry

open access: yesPharmaceuticals, 2023
The Pd–Xantphos-mediated 11C-carbonylation protocol (also known as the “Xantphos- method”), due to its simplistic and convenient nature, has facilitated researchers in meeting a longstanding need for preparing 11C-carbonyl-labeled radiopharmaceuticals at
Kenneth Dahl   +3 more
doaj   +1 more source

ARAS: an automated radioactivity aliquoting system for dispensing solutions containing positron-emitting radioisotopes. [PDF]

open access: yes, 2016
BackgroundAutomated protocols for measuring and dispensing solutions containing radioisotopes are essential not only for providing a safe environment for radiation workers but also to ensure accuracy of dispensed radioactivity and an efficient workflow ...
Carroll, Lewis   +4 more
core   +2 more sources

Enzymatic transhalogenation of dendritic RGD peptide constructs with the fluorinase [PDF]

open access: yes, 2016
We thank EPSRC and the Scottish Imaging Network (SINAPSE) for grants. DO’H thanks the Royal Society for a Wolfson Research Merit Award and ST is grateful to the John and Kathleen Watson Scholarship for financial support.
Fleming, Ian N.   +2 more
core   +1 more source

On the identification of Ti-Ta-Nb-oxides in “wiikites” from Karelia [PDF]

open access: yes, 2018
Purpose. With respect to the nature of Ti-Ta-Nb-oxides, which are included in the mineral associations that have historically gone by the now outdated name of “wiikites”, there is no unanimity of opinion.
Bogdanov, R   +5 more
core   +1 more source

Development of Customized [18F]Fluoride Elution Techniques for the Enhancement of Copper-Mediated Late-Stage Radiofluorination

open access: yesScientific Reports, 2017
In a relatively short period of time, transition metal-mediated radiofluorination reactions have changed the PET radiochemistry landscape. These reactions have enabled the radiofluorination of a wide range of substrates, facilitating access to ...
Andrew V. Mossine   +5 more
doaj   +1 more source

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