Results 21 to 30 of about 12,416 (242)

Radiochemistry: A Hot Field with Opportunities for Cool Chemistry

open access: yesACS Central Science, 2023
Recent Food and Drug Administration (FDA) approval of diagnostic and therapeutic radiopharmaceuticals and concurrent miniaturization of particle accelerators leading to improved access has fueled interest in the development of chemical transformations ...
G. Bowden, Pete Scott, E. Boros
semanticscholar   +1 more source

Cerenkov Luminescence Imaging in the Development and Production of Radiopharmaceuticals

open access: yesFrontiers in Physics, 2021
Over the past several years there has been an explosion of interest in exploiting Cerenkov radiation to enable in vivo and intraoperative optical imaging of subjects injected with trace amounts of radiopharmaceuticals.
R. Michael van Dam   +3 more
doaj   +1 more source

Design and Manufacture of a Test Device for Radiosynthesizer Vacuum Pumps

open access: yesInstruments, 2023
Vacuum pump wear is the most prevalent failure mode of the IBA Synthera® automated radiochemistry system. Rebuilding or replacing the pump causes equipment downtime and increases the radiation exposure of the service personnel.
Victor Amador Diaz   +2 more
doaj   +1 more source

Accelerating radiochemistry development: Automated robotic platform for performing up to 64 droplet radiochemical reactions in a morning.

open access: yesChemical Engineering Journal, 2023
The growing discovery and development of novel radiopharmaceuticals and radiolabeling methods requires an increasing capacity for radiochemistry experiments. However, such studies typically rely on radiosynthesizers designed for clinical batch production
Jason Jones   +3 more
semanticscholar   +1 more source

Highlight selection of radiochemistry and radiopharmacy developments by editorial board (January–June 2020)

open access: yesEJNMMI Radiopharmacy and Chemistry, 2021
Background The Editorial Board of EJNMMI Radiopharmacy and Chemistry releases a biyearly highlight commentary to describe trends in the field. Results This commentary of highlights has resulted in 19 different topics selected by each member of the ...
Mohammed Al-Qahtani   +18 more
doaj   +1 more source

Molecular Imaging, Radiochemistry, and Environmental Pollutants

open access: yesJournal of Nuclear Medicine, 2023
The worldwide proliferation of persistent environmental pollutants is accelerating at an alarming rate. Not surprisingly, many of these pollutants pose a risk to human health.
Samantha Delaney   +3 more
semanticscholar   +1 more source

Fluorine-18: Radiochemistry and Target-Specific PET Molecular Probes Design

open access: yesFrontiers in Chemistry, 2022
The positron emission tomography (PET) molecular imaging technology has gained universal value as a critical tool for assessing biological and biochemical processes in living subjects.
Yunze Wang   +3 more
semanticscholar   +1 more source

First GPR119 PET Imaging Ligand: Synthesis, Radiochemistry, and Preliminary Evaluations.

open access: yesJournal of Medicinal Chemistry, 2023
G-protein-coupled receptor 119 (GPR119) has emerged as a promising target for treating type 2 diabetes mellitus. Activating GPR119 improves glucose homeostasis, while suppressing appetite and weight gain.
Avinash H Bansode   +12 more
semanticscholar   +1 more source

Weapons Radiochemistry: Trinity and Beyond [PDF]

open access: yesNuclear Technology, 2021
On July 16, 1945, the Trinity nuclear test exploded in the desert near Alamogordo, New Mexico. A variety of new diagnostic experiments were fielded in an effort to understand the detailed performance of the nuclear device.
S. Hanson, W. Oldham
semanticscholar   +1 more source

Recent Advances of S–18F Radiochemistry for Positron Emission Tomography

open access: yesACS Omega, 2023
The click chemistry of sulfur(VI) fluoride exchange (SuFEx) has facilitated the widespread application of sulfur–fluoride compounds such as sulfonyl fluorides, fluorosulfates, and sulfamoyl fluorides in various fields, especially in the development of ...
Xiaoyun Deng, Xiaohua Zhu
semanticscholar   +1 more source

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