Results 21 to 30 of about 24,433 (235)

Evaluation of [64Cu]Cu-NOTA-PEG7-H-Tz for Pretargeted Imaging in LS174T Xenografts—Comparison to [111In]In-DOTA-PEG11-BisPy-Tz

open access: yesMolecules, 2021
Pretargeted nuclear imaging for the diagnosis of various cancers is an emerging and fast developing field. The tetrazine ligation is currently considered the most promising reaction in this respect. Monoclonal antibodies are often the preferred choice as
Christian B. M. Poulie   +6 more
doaj   +1 more source

ARAS: an automated radioactivity aliquoting system for dispensing solutions containing positron-emitting radioisotopes. [PDF]

open access: yes, 2016
BackgroundAutomated protocols for measuring and dispensing solutions containing radioisotopes are essential not only for providing a safe environment for radiation workers but also to ensure accuracy of dispensed radioactivity and an efficient workflow ...
Carroll, Lewis   +4 more
core   +2 more sources

Automated Synthesis of 18F-BCPP-EF {2-tert-Butyl-4-Chloro-5-{6-[2-(2[18F]fluoroethoxy)-Ethoxy]-Pyridin-3-ylmethoxy}-2H-Pyridazin-3-One for Imaging of Mitochondrial Complex 1 in Parkinson’s Disease

open access: yesFrontiers in Chemistry, 2022
Graphical ...
Tanpreet Kaur   +12 more
doaj   +1 more source

On the identification of Ti-Ta-Nb-oxides in “wiikites” from Karelia [PDF]

open access: yes, 2018
Purpose. With respect to the nature of Ti-Ta-Nb-oxides, which are included in the mineral associations that have historically gone by the now outdated name of “wiikites”, there is no unanimity of opinion.
Bogdanov, R   +5 more
core   +1 more source

The Rise of Synaptic Density PET Imaging

open access: yesMolecules, 2020
Many neurological disorders are related to synaptic loss or pathologies. Before the boom of positrons emission tomography (PET) imaging of synapses, synaptic quantification could only be achieved in vitro on brain samples after autopsy or surgical ...
Guillaume Becker   +3 more
doaj   +1 more source

Novel Receptor Tyrosine Kinase Pathway Inhibitors for Targeted Radionuclide Therapy of Glioblastoma

open access: yesPharmaceuticals, 2021
Glioblastoma (GB) remains the most fatal brain tumor characterized by a high infiltration rate and treatment resistance. Overexpression and/or mutation of receptor tyrosine kinases is common in GB, which subsequently leads to the activation of many ...
Julie Bolcaen   +5 more
doaj   +1 more source

18F‐Radiopharmaceutical Diversification Enabled by Deaminative Cross‐Electrophile Couplings

open access: yesAngewandte Chemie, EarlyView.
A general Ni‐mediated (C)sp2–(C)sp3 cross‐coupling expedites access to 18F‐radiopharmaceuticals, essential for positron emission tomography imaging and drug discovery. This late‐stage diversification approach was implemented across three user‐friendly automated protocols affording 18F‐radiotracers in sufficient quantities for imaging.
Isabella F. Ogilvy   +13 more
wiley   +2 more sources

Development of Customized [18F]Fluoride Elution Techniques for the Enhancement of Copper-Mediated Late-Stage Radiofluorination

open access: yesScientific Reports, 2017
In a relatively short period of time, transition metal-mediated radiofluorination reactions have changed the PET radiochemistry landscape. These reactions have enabled the radiofluorination of a wide range of substrates, facilitating access to ...
Andrew V. Mossine   +5 more
doaj   +1 more source

Synthesis of Novel, Dual-Targeting 68Ga-NODAGA-LacN-E[c(RGDfK)]2 Glycopeptide as a PET Imaging Agent for Cancer Diagnosis

open access: yesPharmaceutics, 2021
Radiolabeled peptides possessing an Arg-Gly-Asp (RGD) motif are widely used radiopharmaceuticals for PET imaging of tumor angiogenesis due to their high affinity and selectivity to αvβ3 integrin.
Barbara Gyuricza   +6 more
doaj   +1 more source

The Metamorphosis of Radionuclide Production and Development at Paul Scherrer Institute

open access: yesCHIMIA, 2020
Radionuclide production and development has a long history at the Paul Scherrer Institute (PSI) and dates back to the founding times of its forerunner institutions: the Federal Institute for Reactor Research and the Swiss Institute for Nuclear Research ...
Pascal V. Grundler   +5 more
doaj   +1 more source

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