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Highlight selection of radiochemistry and radiopharmacy developments by editorial board
Background The Editorial Board of EJNMMI Radiopharmacy and Chemistry releases a biannual highlight commentary to update the readership on trends in the field of radiopharmaceutical development.
Jean DaSilva+21 more
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Silicon-[18F]Fluorine Radiochemistry: Basics, Applications and Challenges
Silicon-[18F]fluorine (Si-18F) radiochemistry has recently emerged alongside other unconventional approaches such as aluminum-18F and boron-18F based labeling strategies, reshaping the landscape of modern 18F-radiochemistry. All these novel methodologies
Carmen Wängler+5 more
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Simple and easy way for students to develop a dynamic model on Excel sheet
Radioactive decay is not only important in the field of radiochemistry but also useful as a teaching material for chemical kinetics. Although differential equations are often used to explain how decay rate changes over time, there are many students even ...
Kamata Masahiro, Kamata Asuka
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Radiotracers for Imaging of Fibrosis: Advances during the Last Two Decades and Future Directions
Fibrosis accompanies various pathologies, and there is thus an unmet medical need for non-invasive, sensitive, and quantitative methods for the assessment of fibrotic processes.
Olof Eriksson, Irina Velikyan
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Pretargeted nuclear imaging for the diagnosis of various cancers is an emerging and fast developing field. The tetrazine ligation is currently considered the most promising reaction in this respect. Monoclonal antibodies are often the preferred choice as
Christian B. M. Poulie+6 more
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Radiolabeled peptides possessing an Arg-Gly-Asp (RGD) motif are widely used radiopharmaceuticals for PET imaging of tumor angiogenesis due to their high affinity and selectivity to αvβ3 integrin.
Barbara Gyuricza+6 more
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ARAS: an automated radioactivity aliquoting system for dispensing solutions containing positron-emitting radioisotopes. [PDF]
BackgroundAutomated protocols for measuring and dispensing solutions containing radioisotopes are essential not only for providing a safe environment for radiation workers but also to ensure accuracy of dispensed radioactivity and an efficient workflow ...
Carroll, Lewis+4 more
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Novel Receptor Tyrosine Kinase Pathway Inhibitors for Targeted Radionuclide Therapy of Glioblastoma
Glioblastoma (GB) remains the most fatal brain tumor characterized by a high infiltration rate and treatment resistance. Overexpression and/or mutation of receptor tyrosine kinases is common in GB, which subsequently leads to the activation of many ...
Julie Bolcaen+5 more
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Expanding the Chemistry Palette for Radiotracer Synthesis
The synthesis, characterisation and application of radiolabelled compounds for use in diagnostic and therapeutic medicine requires a diverse skill set. This article highlights a selection of our ongoing projects that aim to provide new synthetic methods ...
Jennifer Lamb+12 more
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