Results 21 to 30 of about 12,648 (203)
Chemical Engineering Journal, 2023 The growing discovery and development of novel radiopharmaceuticals and radiolabeling methods requires an increasing capacity for radiochemistry experiments. However, such studies typically rely on radiosynthesizers designed for clinical batch production
Jason Jones +3 more
semanticscholar +1 more source
Molecules, 2022 [18F]sodium fluoride ([18F]NaF) is recognised to be superior to [99mTc]-methyl diphosphate ([99mTc]Tc-MDP) and 2-deoxy-2-[18F]fluoro-D-glucose ([18F]FDG) in bone imaging. However, there is concern that [18F]NaF uptake is not cancer-specific, leading to a
Hishar Hassan +10 more
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Molecular Imaging, Radiochemistry, and Environmental Pollutants
Journal of Nuclear Medicine, 2023 The worldwide proliferation of persistent environmental pollutants is accelerating at an alarming rate. Not surprisingly, many of these pollutants pose a risk to human health.
Samantha Delaney +3 more
semanticscholar +1 more source
Weapons Radiochemistry: Trinity and Beyond [PDF]
Nuclear Technology, 2021 On July 16, 1945, the Trinity nuclear test exploded in the desert near Alamogordo, New Mexico. A variety of new diagnostic experiments were fielded in an effort to understand the detailed performance of the nuclear device.
S. Hanson, W. Oldham
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Silicon-[18F]Fluorine Radiochemistry: Basics, Applications and Challenges
Applied Sciences, 2012 Silicon-[18F]fluorine (Si-18F) radiochemistry has recently emerged alongside other unconventional approaches such as aluminum-18F and boron-18F based labeling strategies, reshaping the landscape of modern 18F-radiochemistry. All these novel methodologies
Carmen Wängler +5 more
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Fluorine-18: Radiochemistry and Target-Specific PET Molecular Probes Design
Frontiers in Chemistry, 2022 The positron emission tomography (PET) molecular imaging technology has gained universal value as a critical tool for assessing biological and biochemical processes in living subjects.
Yunze Wang +3 more
semanticscholar +1 more source
Fully Automated GMP-Compliant Synthesis of [18F]FE-PE2I
Pharmaceuticals, 2021 In the struggle to understand and accurately diagnose Parkinson′s disease, radiopharmaceuticals and medical imaging techniques have played a major role. By being able to image and quantify the dopamine transporter density, noninvasive diagnostic imaging ...
Klas Bratteby +8 more
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Recent Advances of S–18F Radiochemistry for Positron Emission Tomography
ACS Omega, 2023 The click chemistry of sulfur(VI) fluoride exchange (SuFEx) has facilitated the widespread application of sulfur–fluoride compounds such as sulfonyl fluorides, fluorosulfates, and sulfamoyl fluorides in various fields, especially in the development of ...
Xiaoyun Deng, Xiaohua Zhu
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First GPR119 PET Imaging Ligand: Synthesis, Radiochemistry, and Preliminary Evaluations.
Journal of Medicinal Chemistry, 2023 G-protein-coupled receptor 119 (GPR119) has emerged as a promising target for treating type 2 diabetes mellitus. Activating GPR119 improves glucose homeostasis, while suppressing appetite and weight gain.
Avinash H Bansode +12 more
semanticscholar +1 more source
Molecules, 2021 Pretargeted nuclear imaging for the diagnosis of various cancers is an emerging and fast developing field. The tetrazine ligation is currently considered the most promising reaction in this respect. Monoclonal antibodies are often the preferred choice as
Christian B. M. Poulie +6 more
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